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Dr. Han's clinical interests focus on treatment of infections due to multidrug-resistant organisms, including those due to methicillin-resistant Staphylococcus aureus (MRSA) and carbapenem-resistant Enterobacteriaceae (CRE)

Medical School: Northwestern University Feinberg School of Medicine
Residency: NewYork-Presbyterian/Columbia University Medical Center
Fellowship: Hospital of the University of Pennsylvania

American College of Physicians, National American Society for Microbiology, National Infectious Diseases Society of America, National Multidrug-resistant organisms (MDRO) Advisory Committee, Philadelphia Department of Public Health, Local Society for Healthcare Epidemiology of America (SHEA), National

Hospital Privileges:

• Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
• Penn Medicine Rittenhouse Long-Term Acute Care Hospital: Has privileges to treat patients in the hospital.

Description of Research Expertise:

Dr. Han's research focuses on healthcare-associated infections, antibiotic resistance, and antibiotic use, with a focus on infections due to multidrug-resistant organisms across inter-related healthcare settings (e.g., post-acute care).

Selected Publications:

Han JH, Sullivan N, Leas BF, Pegues DA, Kaczmarek JL, Umscheid CA.: Cleaning hospital room surfaces to prevent healthcare-associated infections: A technical brief Annals of Internal Medicine 163 (8): 598-607,2015.

Manning S, Lautenbach E, Tolomeo P, Han JH: Risk factors for infection with Escherichia coli in nursing home residents colonized with fluoroquinolone-resistant E. coli Infection Control and Hospital Epidemiology 36 (5): 575-7,2015.

Jou JJ, Ebrahim J, Schofer F, Hamilton KW, Stern J, Han JH: Environmental transmission of Clostridium difficile: association between hospital room size and C. difficile infection Infection Control and Hospital Epidemiology 36 (5): 564-8,2015.

Tamma PD, Han JH, Rock C, Harris AD, Lautenbach E, Hsu AJ, Avdic E, Cosgrove SE.: Carbapenem therapy is associated with improved survival compared to piperacillin-tazobactam in patients with ESBL bacteremia Clinical Infectious Diseases 60 (9): 1319-25,2015.

Han JH, Johnston B, Nachamkin I, Tolomeo P, Bilker WB, Mao X, Clabots C, Lautenbach E, Johnson JJ.: Clinical and molecular epidemiology of Escherichia coli sequence type 131 (ST131) among hospitalized patients colonized intestinally with fluoroquinolone-resistant E. coli Antimicrobial Agents and Chemotherapy 58 : 7003-6,2014.

Han JH, Maslow J, Han X, Xie SX, Tolomeo P, Santana E, Carson L, Lautenbach E: Risk factors for the development of gastrointestinal colonization with fluoroquinolone-resistant Escherichia coli in residents of long-term care facilities Journal of Infectious Diseases 209 : 420-5,2014.

Han JH, Bilker WB, Nachamkin I, Zaoutis TE, Coffin SE, Linkin DR, Hu B, Tolomeo P, Fishman NO, Lautenbach E: The effect of a hospital-wide urine culture screening intervention on the incidence of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella species Infection Control and Hospital Epidemiology 34 (11): 1160-66.,2013.

Han JH, Bilker WB, Nachamkin I, Tolomeo P, Mao X, Fishman NO, Lautenbach E: Impact of antibiotic use during hospitalization on the development of gastrointestinal colonization with Escherichia coli with reduced fluoroquinolone susceptibility Infection Control and Hospital Epidemiology 34 (10): 1070-6,2013.

Han JH, Nachamkin I, Tolomeo P, Mao X, Bilker WB, Lautenbach E: Temporal changes in resistance mechanisms in colonizing Escherichia coli isolates with reduced susceptibility to fluoroquinolones Diagnostic Microbiology and Infectious Diseases 76 (4): 491-6,2013.

Han JH, Edelstein PH, Bilker WB, Lautenbach E: The effect of staphylococcal cassette chromosome mec (SCCmec) type on clinical outcomes in methicillin-resistant Staphylococcus aureus bacteremia The Journal of Infection 66 (1): 41-7,2013.