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Adults (18-65), Geriatrics (65+)
Adults (18-65), Geriatrics (65+)
Perelman Center for Advanced Medicine
West Pavilion, 1st Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
A facility of the Hospital of the University of Pennsylvania
C. Aggarwal, J.C Thompson, A. Chien, K. Quin, W. Hwang, T. Black, S.S. Yee, T. Christensen, M. LaRiviere, B. Silva, K. Banks, R. Nagy, E. Helman, A. Berman, C.A. Ciunci, A. Singh, J. Wasser, J.M. Bauml, C.J. Langer, R. B. Cohen, E.L. Carpenter: Baseline plasma tumor mutation burden predicts response to pembrolizumab-based therapy in patients with metastatic non-small cell lung cancer Clinical Cancer Research : 2020.
J.C. Thompson, W. Hwang, C. Davis, C. Deshpande, S. Jeffries, Y. Rajpurohit, V. Krishna, D. Smirnov, R. Verona, M.V. Lorenzi, C.J. Langer, S.M. Albelda: Gene Signatures of Tumor Inflammation and Epithelial-to-Mesenchymal Transition (EMT) Predict Responses to Immune Checkpoint Blockade in Lung Cancer with High Accuracy Lung Cancer : 2019.
C. Aggarwal*, J.C Thompson*, T. Black, S. Katz, R. Fan, S.S Yee, A. Chien, T.L. Evans, J. Bauml, E. Alley, C. Ciunci, A. Berman, R. Cohen, D. Lieberman, K. Majmundar, S.L Savitch, J.D. Morrissette, W. Hwang, K. Elenitoba-Johnson, C.J. Langer, E.L. Carpenter.: Clinical implications of plasma-based genotyping with the delivery of personalized therapy in metastatic non–small cell lung cancer. JAMA Oncology 5 (2): 173-180,2019.
J. Kargl, X. Zhu, H. Zhang, G. Yang, T. Riesen, M. Shipley, D. Maeda, J. Zebala, J. Mckay-Fleisch, G. Meredith, A. Mashadi-Hossein, C. Baik, R.H. Pierce, M.W. Redman, J.C. Thompson, S.M. Albelda, H. Bolouri, A.M. Houghton: Neutrophil content predicts lymphocyte depletion and anti-PD1 treatment failure in NSCLC JCI Insight : 2019.
Klampatsa S. O’Brien, J. C. Thompson, S. A.S. Rao, J.E. Standalick, M. Martinez, M. Liousia, E. Cantu, K. Cengel, E. Moon E, S. Singhal, E.B. Eruslanov, S.M Albelda: Phenotypic and Functional Analysis of Malignant Mesothelioma Tumor-Infiltrating Lymphocytes (TILs) Oncoimmunology : 2019.
C. Aggarwal, C. Davis, R. Mick, J.C. Thompson, S. Ahmed, S. Jeffries, S. Bagley, P. Gabriel, T.L. Evans, J. Bauml, C. Ciunci, E. Alley, J.D. Morrissette, R. Cohen, E.L. Carpenter, C. Langer: Influence of TP53 Mutation on Survival and Transformation to Small Cell Lung Cancer in Patients with Advanced EGFR-Mutant Non-Small Cell Lung Cancer JCO Precision Oncology published on line : 2018.
S.M Obrien, A. Klampatsa, J.C.Thompson, M. Martinez, W. Hwang, A. Rao, J. Standalick, S. Kim, E. Cantu, L. Litzky, S. Singhal, E. Eruslanov, E.K. Moon, S.M. Albelda: Function of Human Tumor Infiltrating Lymphocytes in Early Stage Non-Small Cell Lung Cancer Cancer Immunology Research : 2019.
J.C. Thompson, R. Fan, T. Black, G.H. Yu, S.L. Savitch, A. Chien, S. Yee, M. Sen, W. Hwang, S.I. Katz, M. Feldman, A. Vachani, E.L. Carpenter.: Measurement and Immunophenotyping of pleural EpCAM-positive cells and clusters for the management of non-small cell lung cancer patients. Lung Cancer 127 : 25-33,2019.
M. Marmarelis, E. Bange, W. Hwang, Y. Yang, J.C. Thompson, J. Rosenbaum, J. Bauml, C.Ciunci, E. Alley, R. Cohen, C. Langer, E. Carpenter, C. Aggarwal: Impact of KRAS and TP53 co-mutations on outcomes following first-line systemic among patient with STK11 mutated advanced NSCLC JCO Precision Oncology : 2019.
M. Marmarelis, J.C. Thompson, C. Aggarwal, T.L. Evans, E. Carpenter. R.B. Cohen, C.J. Langer, J. Bauml.: Emerging uses of circulating tumor DNA in advanced stage non-small cell lung cancer.
Ann Transl Med.
5 (18): 380,2017.
S. Katz, M. Hammer, S.J. Bagley, C. Aggarwal, J. Bauml, J.C. Thompson, A.C. Nachiappan, C.B. Simone, C. Langer.: Radiologic pseudoprogression during anti-PD1 therapy for advanced non-small lung cancer. J Thorac Oncol.
13 (7): 978-986,2018.
J. C. Thompson, S.S Yee, A.B. Troxel, S.L. Savitch, R. Fan, D. Balli, D.B. Lieberman, J.D Morrissette, T.L Evans, J. Bauml, C. Aggarwal, J.A Kosteva, E. Alley, C. Ciunci, R.B. Cohen, S. Bagley, S. Stonehouse-Lee, V.E. Sherry, E. Gilbert, C. Langer, A. Vachani, E. Carpenter: Detection of Therapeutically Targetable Driver and Resistance Mutations in Lung Cancer Patients by Next-Generation Sequencing of Cell-Free Circulating Tumor DNA. Clinical Cancer Research 22 (23): 5772-5782,2016.
S.J. Bagley, S. Kothari, C. Aggarwal, J. Bauml, E. Alley, T.L Evans, J.A. Kosteva, C. Ciunci, J.C. Thompson, S. Stonehouse-Lee, V.E. Sherry, E. Gilbert, B. Sandy, F. Mutale, G. DiLullo, R.B. Cohen, A. Vachani, C. Langer.: Pretreatment neutrophil-to-lymphocyte ratio as a marker of outcomes in nivolumab treated patients with advanced non-small cell lung cancer. Lung Cancer 106 : 1-7,2017.
DE Schwed Lustgarten, J.C. Thompson, G Yu, A Vachani, B Vaidya, C Rao, M Connelly, M Udine, KS Tan, D. Heitjan, S Albelda: Use of circulating tumor cell technology (CELLSEARCH) for the diagnosis of malignant pleural effusions. Annals of the American Thoracic Society 10 (6): 582-9,2013.
221 Stemmler Hall3450 Hamilton Walk
Patient appointments: 800-789-7366