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Jeffrey C. Thompson, MD

Jeffrey C. Thompson, MD Physician

Assistant Professor of Medicine at the Hospital of the University of Pennsylvania and the Veteran's Administration Medical Center

Dr. Thompson is employed by Penn Medicine.

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Clinical Specialties


  • Pulmonary Medicine

Programs & Centers:

Board Certification:

  • Internal Medicine, 2013
  • Pulmonary Disease, 2016

Clinical Expertise:

  • Airway Disorders
  • Airway Obstruction
  • Bronchoscopy
  • Drug-Induced Pulmonary Disease
  • Emphysema
  • Empyema
  • Hemoptysis
  • Hepatic Hydrothorax
  • Lung Cancer Screening
  • Lung Nodule
  • Lung Tumors
  • Needle Procedure
  • Pleural Diseases
  • Pleural Effusion (Fluid in the Lung)
  • Pleural Thickening
  • Pleural Tuberculosis
  • Pulmonary Function Tests
  • Radiation Pneumonitis
  • Tracheal Mass
  • Tracheal Stenosis
  • Wheezing
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Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of Alabama
Residency: Hospital of the University of Pennsylvania
Fellowship: Hospital of the University of Pennsylvania


Advisory Board. Guardant Health Early Detection Platform, National American Association for Cancer Research, National American Thoracic Society, Member (Thoracic Oncology Assembly), International Institutional Review Board #6, Member, University of Pennsylvania, Local

Hospital Affiliation

Dr. Thompson is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Rittenhouse Long-Term Acute Care Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Selected Publications:

J.C. Thompson, R. Fan, T. Black, G.H. Yu, S.L. Savitch, A. Chien, S. Yee, M. Sen, W. Hwang, S.I. Katz, M. Feldman, A. Vachani, E.L. Carpenter.: Measurement and Immunophenotyping of pleural EpCAM-positive cells and clusters for the management of non-small cell lung cancer patients. Lung Cancer 127 : 25-33,2019.

C. Aggarwal*, J.C Thompson*, T. Black, S. Katz, R. Fan, S.S Yee, A. Chien, T.L. Evans, J. Bauml, E. Alley, C. Ciunci, A. Berman, R. Cohen, D. Lieberman, K. Majmundar, S.L Savitch, J.D. Morrissette, W. Hwang, K. Elenitoba-Johnson, C.J. Langer, E.L. Carpenter.: Clinical implications of plasma-based genotyping with the delivery of personalized therapy in metastatic non–small cell lung cancer. JAMA Oncology 5 (2): 173-180,2019.

C. Aggarwal, C. Davis, R. Mick, J.C. Thompson, S. Ahmed, S. Jeffries, S. Bagley, P. Gabriel, T.L. Evans, J. Bauml, C. Ciunci, E. Alley, J.D. Morrissette, R. Cohen, E.L. Carpenter, C. Langer: Influence of TP53 Mutation on Survival and Transformation to Small Cell Lung Cancer in Patients with Advanced EGFR-Mutant Non-Small Cell Lung Cancer JCO Precision Oncology published on line : 2018.

S. Katz, M. Hammer, S.J. Bagley, C. Aggarwal, J. Bauml, J.C. Thompson, A.C. Nachiappan, C.B. Simone, C. Langer.: Radiologic pseudoprogression during anti-PD1 therapy for advanced non-small lung cancer. J Thorac Oncol. 13 (7): 978-986,2018.

A. Klampatsa, S. O’Brien, E. Eruslanov, A. Rao, J.C. Thompson, S. Kim, K. Cengel, E. Moon, S. Singhal, S. Albelda: Phenotypic and Functional Analysis of Malignant Mesothelioma Tumor-Infiltrating Lymphocytes (TILs). Internal Conference of the International Mesothelioma Interest Group. Ottawa, Canada. : 2018.

E. Moon. S. O’brien, J.C. Thompson, S. Kim, K. Ma, D. Dibardino. A. Lanfranco, A. Vachani, A. Haas, S. Albelda.: A Pilot study of endobronchial guided transbronchial needle aspiration for immunophenotyping the lung cancer tumor microenvironment. American Thoracic Society Conference. San Diego, CA. : 2018.

J.C.Thompson, S.L. Savitch, R. Fan, S.S Yee, C.A. Powers, G. Yu, L. Gebrian, D. Smirnov, C. Rao, S. Gross, M. Feldman, A. Vachani, E.L. Carpenter: The use of circulating tumor cell technology for the characterization of tumor cells and assessment of PD-L1 expression in pleural effusions of metastatic non-small cell lung cancer patients. Association of Clinical and Translational Science. Washington, D.C. : 2018.

E. Bange*, M. Marmarelis*, W. Hwang, Y. Yang, J.C. Thompson, J. Bauml, C.Ciunci, E. Alley, T. Evans, J. Morrissette, R. Cohen, C. Langer, E. Carpenter, C. Aggarwal.: Impact of KRAS and TP53 co-mutations on outcomes following 1st-line therapy among patient with LKB1/STK11 mutated stage IV NSCLC. American Association for Cancer Research Annual Meeting, Chicago, IL. : 2018.

M. Marmarelis, J.C. Thompson, C. Aggarwal, T.L. Evans, E. Carpenter. R.B. Cohen, C.J. Langer, J. Bauml.: Emerging uses of circulating tumor DNA in advanced stage non-small cell lung cancer. Ann Transl Med. 5 (18): 380,2017.

S.J. Bagley, S. Kothari, C. Aggarwal, J. Bauml, E. Alley, T.L Evans, J.A. Kosteva, C. Ciunci, J.C. Thompson, S. Stonehouse-Lee, V.E. Sherry, E. Gilbert, B. Sandy, F. Mutale, G. DiLullo, R.B. Cohen, A. Vachani, C. Langer.: Pretreatment neutrophil-to-lymphocyte ratio as a marker of outcomes in nivolumab treated patients with advanced non-small cell lung cancer. Lung Cancer 106 : 1-7,2017.

DE Schwed Lustgarten, J.C. Thompson, G Yu, A Vachani, B Vaidya, C Rao, M Connelly, M Udine, KS Tan, D. Heitjan, S Albelda: Use of circulating tumor cell technology (CELLSEARCH) for the diagnosis of malignant pleural effusions. Annals of the American Thoracic Society 10 (6): 582-9,2013.

J. C. Thompson, S.S Yee, A.B. Troxel, S.L. Savitch, R. Fan, D. Balli, D.B. Lieberman, J.D Morrissette, T.L Evans, J. Bauml, C. Aggarwal, J.A Kosteva, E. Alley, C. Ciunci, R.B. Cohen, S. Bagley, S. Stonehouse-Lee, V.E. Sherry, E. Gilbert, C. Langer, A. Vachani, E. Carpenter: Detection of Therapeutically Targetable Driver and Resistance Mutations in Lung Cancer Patients by Next-Generation Sequencing of Cell-Free Circulating Tumor DNA. Clinical Cancer Research 22 (23): 5772-5782,2016.

Academic Contact Info

221 Stemmler Hall
3450 Hamilton Walk

Philadelphia, PA 19104
Phone: (215) 898-3168
Patient appointments: 800-789-7366 (PENN)