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Jeffrey B. Doyon, MD, PhD Physician

Director of Antimicrobial Stewardship at the Corporal Michael J. Crescenz VAMC Assistant Professor of Clinical Medicine

Dr. Doyon is employed by Penn Medicine.

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Clinical Specialties


  • Infectious Diseases

Programs & Centers:

Board Certification:

  • Internal Medicine, 2017

Clinical Expertise:

  • AIDS
  • Anal Pap Smear
  • Antiretroviral Salvage Therapy
  • Aspergillosis
  • Bone Infection (Osteomyelitis)
  • C. Difficile (Clostridium Difficile Diarrhea)
  • Cellulitis
  • Encephalitis
  • Fever of Unknown Origin
  • Flu (Influenza)
  • Flu Shot Vaccination
  • Fungal Meningitis
  • Fungemia
  • Genital Warts (Condyloma Acuminatum)
  • Gonorrhea
  • Hepatitis
  • Hepatitis A Vaccination
  • Hepatitis B
  • Hepatitis B Vaccination
  • Hepatitis C
  • Herpes Simplex Virus (HSV)
  • Histoplasmosis
  • HIV and AIDS
  • HPV Vaccination
  • Human Papilloma Virus
  • Japanese Encephalitis Vaccination
  • Joint Infection
  • Lyme Disease
  • Lymphogranuloma Venereum
  • Malaria
  • Measles Vaccination
  • Meningitis
  • Meningitis Vaccination
  • Menningococcal Vaccine
  • MMR Vaccine
  • Mycobacterium
  • Mycobacterium Avium Complex
  • Mycoplasma
  • Mycosis
  • Parasitic Diseases
  • Pneumonia
  • Pneumonia Vaccination
  • Polio Vaccination
  • Pre-Exposure Prophylaxis
  • Prosthetic Joint Infection
  • Pyelonephritis
  • Rabies Vaccination
  • Sexually Transmitted Diseases (STD)
  • Shingles
  • Shingles Vaccination
  • Staph Infection
  • Swollen Lymph Nodes
  • Syphilis
  • Transplant Related Infection
  • Travel Medicine
  • Travel Vaccination
  • Travelers' Diarrhea
  • Tropical Medicine
  • Tuberculosis (TB)
  • Tuberculosis Testing
  • Typhoid Fever Vaccination
  • Viral Encephalitis
  • Viral Meningitis
  • Wound Infection
  • Yellow Fever Vaccination
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Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of California - San Francisco
Residency: Brigham and Women's Hospital
Fellowship: Hospital of the University of Pennsylvania


American Society of Transplantation, National Infectious Diseases Society of America, National

Hospital Affiliation

Dr. Doyon is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Selected Publications:

Doyon JB, Zeitler B, Cheng J, Cheng AT, Cherone JM, Santiago Y, Lee AH, Vo TD, Doyon Y, Miller JC, Paschon DE, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Drubin DG: Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells Nat Cell Biol 13 (3): 331-7,2011.

Doyon JB, Liu DR: Identification of eukaryotic promoter regulatory elements using nonhomologous random recombination Nucleic Acids Res 35 (17): 5851-60,2007.

Doyon JB, Pattanayak V, Meyer CB, Liu DR: Directed evolution and substrate specificity profile of homing endonuclease I-SceI J Am Chem Soc 128 (7): 2477-84,2006.

Gartner ZJ, Tse BN, Grubina R, Doyon JB, Snyder TM, Liu DR: DNA-templated organic synthesis and selection of a library of macrocycles Science 305 (5690): 1601-5,2004.

Doyon JB, Snyder TM, Liu DR: Highly sensitive in vitro selections for DNA-linked synthetic small molecules with protein binding affinity and specificity J Am Chem Soc 125 (41): 12372-3,2003.

Madder RD, Kim C-Y, Chandra PP, Doyon JB, Baird TA, Fierke CA, Christianson DW, Voet JG, Jain A: Twisted amides inferred from QSAR analysis of hydrophobicity and electronic effects on the affinity of fluoroaromatic inhibitors of carbonic anhydrase J Org Chem 67 (2): 582-4,2002.

Mattoon D, Gupta K, Doyon J, Loll PJ, DiMaio D: Identification of the transmembrane dimer interface of the bovine papillomavirus E5 protein Oncogene 20 (29): 3824-34,2001.

Kim CY, Chang JS, Doyon JB, Baird TT, Fierke CA, Jain A, Christianson DW: Contribution of Fluorine to Protein−Ligand Affinity in the Binding of Fluoroaromatic Inhibitors to Carbonic Anhydrase II J Am Chem Soc 122 (49): 12125-12134,2000.

Doyon JB, Hansen EA, Kim CY, Chang JS, Christianson DW, Madder RD, Voet JG, Baird TA, Fierke CA, Jain A: Linear free energy relationships implicate three modes of binding for fluoroaromatic inhibitors to a mutant of carbonic anhydrase II Org Lett 2 (16): 2557-8,2000.

Doyon JB, Hansen EA, Kim CY, Chang JS, Christianson DW, Madder RD, Voet JG, Baird TA, Fierke CA, Jain A: Linear free energy relationships implicate three modes of binding for fluoroaromatic inhibitors to a mutant of carbonic anhydrase II Org Lett 2 (9): 1189-92,2000.

Academic Contact Info

Room a806, 8th Floor Medicine Administration Wing, VAMC
Philadelphia, PA 19104
Patient appointments: 800-789-7366 (PENN)