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Jeff Mandel, MD

Jeff Mandel, MD Physician

Assistant Professor of Anesthesiology and Critical Care at the Hospital of the University of Pennsylvania

Dr. Mandel is employed by Penn Medicine.

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Clinical Specialties


  • Anesthesiology

Programs & Centers:

Board Certification:

  • Anesthesiology, 1985

Description of Clinical Expertise

Dr. Mandel specializes in anesthesia for otorhinolaryngologic procedures, particularly procedures of the trachea and larynx. He has special expertise in high frequency jet ventilation and total intravenous anesthesia. He has also been involved in developing new methods for sedation in GI endoscopy, interventional pulmonary procedures, and cardiac electrophysiology procedures.

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: University of Texas - Southwest
Residency: Baylor College of Medicine
Residency: Hospital of the University of Pennsylvania
Residency: Ohio State University Hospital
Fellowship: University of California, San Diego


American Society of Anesthesiology, National International Society for Anesthetic Pharmacology, International Society for Technology in Anesthesia, International

Hospital Affiliation

Dr. Mandel is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Dr. Mandel has expertise in adaptive optimal control theory and pharmacokinetic modelling. He has conducted research in patient-controlled sedation.

Selected Publications:

Mandel Jeff E: Understanding Infusion Pumps. Anesthesia and analgesia 126 (4): 1186-1189,2018.

Atkins Joshua H, Mandel Jeff E: Drug-induced sleep endoscopy: from obscure technique to diagnostic tool for assessment of obstructive sleep apnea for surgical interventions. Current opinion in anaesthesiology 31 (1): 120-126,2018.

Mandel Jeff E, Stevenson William G, Frankel David S: Anesthesia in the Electrophysiology Laboratory. Anesthesiology clinics 35 (4): 641-654,2017.

Mandel JE, Tietäväinen A, Otero J and Hæggström E: A simple posturographic method detects the difference in recovery of patients receiving endoscopic sedation with propofol vs. midazolam Medical Research and Innovations 1 (2): 1-4,2017.

Mandel Jeff E: Safe Driving on the Pharmacokinetic Highway. Anesthesia and analgesia 125 (4): 1100-1101,2017.

Atkins, JH, Haas, AR, Sterman, DH, Vachani, A, Mandel, JE: A randomized, placebo-controlled, concealed allocation comparison of respiratory depression during bronchoscopy with dexmedetomidine-ketamine as an adjunct to fentanyl-midazolam sedation Transl Perioper & Pain Med 1 (1): 1-8,2016.

Mandel JE, Atkins JH: Hilbert-Huang transform yields improved minute volume estimates from respiratory inductance plethysmography during transitions to paradoxical breathing Anesthesia & Analgesia 122 (1): 126-31,2016.

Mandel Jeff E: Infusion systems: the infrastructure of modern anesthesia. Anesthesia and analgesia 120 (6): 1178,2015.

Mountantonakis SE, Elkassabany N, Kondapalli L, Marchlinski FE, Mandel JE, Hutchinson MD: Provocation of atrial fibrillation triggers during ablation: does the use of general anesthesia affect inducibility? Journal of cardiovascular electrophysiology 26 (1): 16-20,2015.

Mandel, JE: Application of pharmacokinetic and pharmacodynamic modeling to guide propofol administration for endoscopy procedures Clinical Pharmacology for Anesthesiology : 427-436,2015.

Academic Contact Info

Department of Anesthesiology & Critical Care
7 Dulles
3400 Spruce Street
Hospital of the University of Pennsylvania

Philadelphia, PA 19104
Phone: (215) 615-0553

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