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Jay Pathmanathan, MD, PhD

Jay Pathmanathan, MD, PhD Physician

Director of Electroencephalography, Penn Epilepsy Fellowship Director Assistant Professor of Clinical Neurology

Dr. Pathmanathan is employed by Penn Medicine.

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About Dr. Jay Pathmanathan

Recognized in Philadelphia magazine's May 2019 Top Docs issue

Clinical Specialties


  • Neurology

Programs & Centers:

Board Certification:

  • Addiction Psychiatry, 2013
  • Neurology, 2009

Clinical Expertise:

  • Abnormal EEG
  • Absence Epilepsy
  • Ambulatory EEG
  • Atonic Epilepsy
  • Convulsion
  • Cryptogenic Epilepsy
  • Deep Brain Stimulation
  • Drop Attack
  • Electroencephalography
  • Epilepsy
  • Epilepsy Monitoring Unit Evaluation (Emu)
  • Epileptic Confusional State
  • Epileptic Twilight State
  • Evaluation for Epilepsy Surgery
  • Familial Epilepsy
  • First Seizure Clinic
  • Focal Seizures
  • Frontal Lobe Epilepsy
  • Generalized Seizures
  • Grand Mal Seizures
  • Juvenile Myoclonic Epilepsy
  • Landau-Kleffner Syndrome
  • Lennox-Gastaut Syndrome
  • Maternal Seizures
  • Mesial Temporal Sclerosis
  • Myoclonic Seizures
  • New Onset Seizure
  • Occipital Lobe Epilepsy
  • Parietal Lobe Epilepsy
  • Petit Mal Seizure
  • Post-Traumatic Epilepsy
  • Post-Traumatic Seizure
  • Progressive Myoclonic Epilepsy
  • Responsive Neurostimulation
  • Simple Partial Seizures
  • Status Epilepticus
  • Temporal Lobe Epilepsy
  • Vagus Nerve Stimulation
  • Visualase MRI-Guided Laser Ablation
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Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of Connecticut
Residency: Brigham and Women's Hospital
Fellowship: Massachusetts General Hospital


American Academy of Neurology, National American Clinical Neurophysiological Society, National American Epilepsy Society, National

Hospital Affiliation

Dr. Pathmanathan is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

-Medical education research focusing on computational tools
-Quantitative EEG research including ICU And intracranial EEG

Selected Publications:

Weber D, McCarthy D, Pathmanathan J: An effective automated method for teaching EEG interpretation to neurology residents. Seizure (40): 10-12,2016.

Chu CJ, Leahy J, Pathmanathan J, Kramer MA, Cash SS: The maturation of cortical sleep rhythms and networks over early development Clin Neurophysiol 125 (7): 1360-70,2014.

Karakis I, Pathmanathan J, Chang R, Cook E, Cash S, Cole A: The prognostic value of EEG asymmetries for the development of pharmaco-resistance in medication-naïve patients with idiopathic generalized epilepsies Clin Neurophysiol 125 (2): 263-9,2014.

Chu CJ, Kramer MA, Pathmanathan J, Bianchi MT, Westover MB, Wizon L, Cash SS: Emergence of stable functional networks in long-term human electroencephalography J Neurosci. 2012 Feb 22;32(8):2703-13. 22;32 (8): 2703-13,2012.

Karakis I, Velez-Ruiz N, Pathmanathan JS, Sheth SA, Eskandar EN, Cole AJ: Foramen ovale electrodes in the evaluation of epilepsy surgery: Conventional and unconventional uses Epilepsy Behav 22 (2): 247-54,2011.

Pathmanathan J, Parkerson KA, Milligan TA: Case Studies in Optimizing Antiepileptic Treatment J Clin Outcomes Manage 2009 16(12):573-582 16 (12): 573-82,2009.

Parkerson KA, Pathmanathan J, Milligan TA: Optimizing anti- epileptic treatment J Clin Outcomes Manage 16 (1): 468-80,2009.

Bianchi MT, Pathmanathan J, Cash SS: From ion channels to complex networks: magic bullet versus magic shotgun approaches to anticonvulsant pharmacotherapy Med Hypotheses. 2009 Mar;72(3):297-305 72 (3): 297-305,2009.

Pathmanathan JS, Presnel R, Cromer JA, Cullen KE, and Waitzman DM: Spatial characteristics of neurons in the central mesencephalic reticular formation (cMRF) of head-unrestrained monkeys Exp Brain Res 168 (4): 455-70,2006.

Pathmanathan JS, Cromer JA, Cullen KE, and Waitzman DM: Temporal characteristics of neurons in the central mesencephalic reticular formation of head unrestrained monkeys Exp Brain Res 168 (4): 471-92,2006.

Academic Contact Info

Department of Neurology
150 S Huntington Ave

Boston, MA 02130
Patient appointments: 800-789-7366 (PENN)

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