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James K. Mangan, MD, PhD

James K. Mangan, MD, PhD Physician

Assistant Professor of Clinical Medicine

Languages spoken:

  • Spanish

Dr. Mangan is a Penn Medicine employed physician.

Clinical Specialties

Specialty:

  • Medicine
    • Hematology
    • Medical Oncology

Programs & Centers:

Board Certification:

  • Hematology, 2011
  • Internal Medicine, 2008

Clinical Expertise:

  • Bone Marrow Transplant
  • Leukemia
  • Multiple Myeloma
  • Stem Cell Transplant

Practice Locations and Appointments

  • Abramson Cancer Center

    Perelman Center for Advanced Medicine West Pavilion, 2nd Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-PENN (7366)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Temple University School of Medicine
Residency: University of Michigan Medical Center
Fellowship: Hospital of the University of Pennsylvania

Memberships

American Society for Blood and Marrow Transplantation, National American Society of Hematology, National

Hospital Affiliation

Dr. Mangan is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.

Research

Selected Publications:

Reshef R, Huffman AP, Gao A, Luskin MR, Frey NV, Gill SI, Hexner EO, Kambayashi T, Loren AW, Luger SM, Mangan JK, Nasta SD, Richman LP, Sell M, Stadtmauer EA, Vonderheide RH, Mick R, Porter DL: High graft CD8 cell dose predicts improved survival and enables better donor selection in allogeneic stem-cell transplantation with reduced-intensity conditioning. J Clin Oncol 33 (21): 2392-2398,2015.

Bagley SJ, Sehgal AR, Gill S, Frey NV, Hexner EO, Loren AW, Mangan JK, Porter DL, Stadtmauer EA, Reshef R, Luger SM.: Acute cholecystitis is a common complication after allogeneic stem cell transplantation and is associated with the use of total parenteral nutrition. Biol Blood Marrow Transplant 21 (4): 768-771,2015.

Orlowski, RJ, Mangan JK, Luger SM.: Approach to patients with primary refractory acute myeloid leukemia. Curr Opin Hematol 22 (2): 97-107,2015.

Yam C, Crisalli L, Luger S, Loren A, Hexner EO, Frey N, Mangan J, Gao A, Stadtmauer EA, Porter D, and Reshef R.: Unrelated donors are associated with improved relapse free survival compared to related donors in patients with myelodysplastic syndrome undergoing reduced intensity conditioned allogeneic stem-cell transplantation. American Society of Hematology Annual Meeting (4380): 2015.

Orlowski R, Huang A, Gohil M, Mangan J, Vignali M, Emerson RO, Robins H, Yusko E, Jordan MS, Carroll M, and Gilliland DG.: Integrated immunological analysis of the bone marrow tumor microenvironment in myeloproliferative neoplasms to determine potential efficacy of immune checkpoint blockade. American Society of Hematology Annual Meeting (2766): 2015.

Mesa RA, Miller CB, Mascarenhas JO, Thyne M, Goldberger S, Parangama DC, Parasuraman SV, Fazal S, Naim AB, and Mangan J.: Hydroxyurea treatment history and quality of life in patients with polycythemia vera: results from the MPN Landmark Survey in the United States. American Society of Hematology Annual Meeting (4077): 2015.

Reshef R, Huffman AP, Gao A, Sell M, Luskin M, Luger S, Loren A, Hexner EO, Nasta SD, Frey NV, Gill S, Mangan J, Richman LP, Kambayashi T, Stadtmauer EA, Vonderheide RH, Mick R, Porter DL: A survival benefit for reduced intensity allogeneic transplants from young unrelated donors compared to older sibling donors depends on the graft CD8 T-Cell content. American Society of Bone Marrow Transplantation/Center for International Bone Marrow Transplantation Research Tandem Meetings : 2015.

Canaani J, Luskin MR, Loren A, Timlin C, Mangan J, Hexner EO, Frey NV, Porter DL, Stadtmauer EA, and Luger S.: Outcome of patients with acute myeloid leukemia treated with salvage high-dose cytarabine monotherapy. American Society of Hematology Annual Meeting (2543): 2015.

Reshef R, Hexner EO, Loren AW, Frey NV, Stadtmauer EA, Luger SM, Mangan JK, Gill SI, Vassilev P, Smith J, Van Deerlin VM, Mick R, and Porter DL: Early donor chimerism levels predict relapse and survival after allogeneic stem cell transplantation with reduced intensity conditioning Biol Blood Marrow Transplant 20 (11): 2014.

Reshef R, Huffman AP, Gao A, Sell M, Luskin MR, Luger SM, Loren AW, Hexner EO, Nasta SD, Frey NV, Gill SI, Mangan J, Richman LP, Kambayashi T, Stadtmauer EA, Vonderheide RH, and Porter DL: CD8 cell dose in peripheral blood stem-cell grafts correlates with relapse and survival after reduced intensity conditioning allogeneic stem cell transplantation American Society of Hematology Annual Meeting (1260): 2014.

Academic Contact Info

Division of Hematology Oncology
Perelman Center for Advanced Medicine
12th Floor, South Pavilion
Office #12-102
34th Street and Civic Center Blvd

Philadelphia, PA 19104
Phone: (215) 615-3138
Fax: (215) 615-5887
Patient appointments: 800-789-PENN (7366)