Description of Research Expertise:
Anti-inflammatory drugs, cyclooxygenases ,prostaglandins, mechanisms of pain
Barnett RE, Fish D, Katragadda R, Mardini IA, O'Grady TJ: A preemptive approach to stop postoperative pain. A symposium Contemporary Surgery 59 (12) : 559-566,2003.
Aksoy MO, Mardini IA, Yang Y, Bin W, Zhou S, Kelsen SG: Glucocorticoid effects on the beta-adrenergic receptor-adenylyl cyclase system of human airway epithelium. The Journal of Allergy and Clinical Immunology 109 (3): 491-7,2002.
McAdam BF, Mardini IA, Habib A, Burke A, Lawson JA, Kapoor S, FitzGerald GA: Effect of regulated expression of human cyclooxygenase isoforms on eicosanoid and isoeicosanoid production in inflammation. The Journal of Clinical Investigation 105 (10): 1473-82,2000.
McAdam BF, Catella-Lawson F, Mardini IA, Kapoor S, Lawson JA, FitzGerald GA: Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. Proceedings of the National Academy of Sciences of the United States of America 96 (1): 272-7,1999.
Kelsen SG, Higgins NC, Zhou S, Mardini IA, Benovic JL: Expression and function of the beta-adrenergic receptor coupled-adenylyl cyclase system on human airway epithelial cells. American Journal of Respiratory and Critical Care Medicine 152 (6 Pt 1): 1774-83,1995.
Kelsen SG, Zhou S, Anakwe O, Mardini IA, Higgins N, Benovic JL: Expression of the beta-adrenergic receptor-adenylyl cyclase system in basal and columnar airway epithelial cells. The American Journal of Physiology 267 (4 Pt 1): L456-63,1994.
Mardini IA, Higgins NC, Zhou S, Benovic JL, Kelsen SG: Functional behavior of the beta-adrenergic receptor-adenylyl cyclase system in rabbit airway epithelium. American Journal of Respiratory Cell and Molecular Biology 11 (3): 287-95,1994.
Kelsen SG, Sexauer WP, Mardini IA, Criner GJ: The comparative effects of elastase-induced emphysema on costal and crural diaphragm and parasternal intercostal muscle contractility. American Journal of Respiratory and Critical Care Medicine 149 (1): 168-73,1994.
Kelsen SG, Bao S, Thomas AJ, Mardini IA, Criner GJ: Structure of parasternal intercostal muscles in the adult hamster: topographic effects. Journal of Applied Physiology (Bethesda, Md.: 1985) 75 (3): 1150-4,1993.
Kelsen SG, Mardini IA, Zhou S, Benovic JL, Higgins NC: A technique to harvest viable tracheobronchial epithelial cells from living human donors. American Journal of Respiratory Cell and Molecular Biology 7 (1): 66-72,1992.