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Farzana Sayani, MD

Farzana Sayani, MD Physician

Director, Penn Comprehensive Adult Thalassemia Program Director, Penn Comprehensive Sickle Cell Program Assistant Professor of Medicine at the Hospital of the University of Pennsylvania

Languages spoken:

  • Gujarati

Dr. Sayani is employed by Penn Medicine.

Patient Satisfaction Ratings

Patient Rating Breakdown

The Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our nationally-recognized Press Ganey Patient Satisfaction Survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.

Responses are measured on a scale of 1 to 5 with 5 being the best score.

Comments are submitted by patients and reflect their views and opinions. The comments are not endorsed by and do not necessarily reflect the views of Penn Medicine.

Overall Ratings

Clinical Specialties


  • Hematology

Programs & Centers:

Board Certification:

  • Hematology, 2012

Clinical Expertise:

  • Anemia
  • Anemia and Bone Marrow Disorders
  • Anemia of Chronic Disease
  • Anemia of Pregnancy
  • Autoimmune Hemolytic Anemia
  • B12 Deficiency Anemia
  • Bone Marrow Biopsy
  • Bone Marrow Failure Syndromes
  • Cold Agglutinin Disease
  • Cooley's Anemia
  • Diamond Blackfan Anemia
  • Dyskeratosis Congenita
  • Fanconi Anemia
  • Folic Acid Deficiency
  • Glucose-6-Phosphate Dehydrogenase Deficiency
  • Hemochromatosis
  • Hemolytic Anemia
  • Hemolytic Uremic Syndrome
  • Heparin-Induced Thrombocytopenia
  • Hereditary Spherocytosis
  • Iron Deficiency Anemia
  • Iron Metabolism Disorders
  • Leukocytosis
  • Leukopenia
  • Lymphopenia
  • Maternal Hematologic Disorders
  • Neutropenia
  • Pancytopenia
  • Paroxysmal Nocturnal Hemoglobinuria
  • Pernicious Anemia
  • Polycythemia
  • Pure Red Cell Aplasia
  • Red Blood Cell Disorders
  • Secondary Polycythemia
  • Splenic Sequestration
  • Splenomegaly
  • Thrombocytopenia
  • Thrombocytosis
  • Thrombotic Thrombocytopenic Purpura
  • Venous-Occlusive Crisis
  • White Blood Cell Disorders
Show All Expertise

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oscar Health Plan of PA
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of Calgary
Residency: University of Alberta
Residency: University of Calgary
Fellowship: University of Toronto Affiliated Hospitals


American Society of Hematology, National Cooleys Anemia Foundation, National Thalassemia Foundation of Canada, International

Hospital Affiliation

Dr. Sayani is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.


Selected Publications:

Shah FT, Sayani F, Trompeter S, Drasar E, Piga A: Challenges of blood transfusions in b-thalassemia. Blood Reviews 37 : 2019.

Farzana Sayani, Payal Desai, Sophie Lanzkron: Thalassemia, sickle cell disease and other hemoglobinopathies. American Society of Hematology Self Assessment Program (ASH-SAP), 7th edition : 2019.

Farzana Sayani and Srikanth Nagalla: Transfusions in Sickle Cell Disease. American Society of Hematology Benign Hematology Curriculum, ASH Academy : 2018.

Farzana Sayani and Rakesh Mehta: Iron Overload in Sickle Cell Disease American Society of Hematology Benign Hematology Curriculum, ASH Academy : 2018.

Boyle SM, Jacobs B, Sayani FA, Hoffman B.: Management of the dialysis patient with sickle cell disease. Seminars in Dialysis. 29 (1): 62-70,2016.

Farzana Sayani and Sophie Lanzkron: Chapter 7: Hemolytic Anemia American Society of Hematology Self Assessment Program (ASH-SAP), 6th edition : 2016.

Gwynivere Davies, Karen Valentine, Zahra Goodarzi, Farzana Sayani: Thrombotic Thrombocytopenic Purpura (TTP) Management at Foothills Medical Centre: A Retrospective Analysis Between 2005-2010 (Tertiary Centre, Calgary) Blood, ASH Annual Meeting Abstracts 126 (23): 4654,2015.

Ahluwalia M, Parmacek MS, Sayani FA1, Vallabhajosyula: Nearly Missed Diagnosis: Postpartum Type B Aortic Dissection American Journal of Medicine 128 (11): 1188-90,2015.

Sayani, FA and Abrams, C: How I treat refractory thrombotic thrombocytopenia purpura. Blood 125 (25): 3860-7,2015.

Sayani F, Goldberg D, Slaven L, Russell JE.: Hepatitis E infection in a patient with transfusion-dependent beta thalassemia. Am J Hematol 90 (3): E50,2015.

Academic Contact Info

3rd Floor Dulles Building
3400 Spruce Street,

Philadelphia, PA 19104
Phone: (215) 615-6555
Patient appointments: 800-789-7366 (PENN)