Description of Research Expertise:
Biomedical image analysis; Quantitative imaging biomarkers; Pattern recognition; Identification, characterization and validation of imaging biomarkers; Evaluation of genotype to phenotype associations via imaging; Integrated diagnostics; Risk prediction; Personalized screening, prognostication and treatment of breast cancer.
E.F. Conant, B.M. Keller, L. Pantalone, A. Gastounioti, E.S. McDonald, D. Kontos: Agreement between Breast Percent Density Estimation from Standard versus Synthetic Digital Mammograms: Results from a Large Screening Cohort Using Automated Measures Radiology 283 (3): 673-680,2017.
B.L. Sprague, E.F. Conant, T. Onega, M.P. Garcia, E.F. Beaber, S.D. Herschorn, C.D. Lehman, A.N.A. Tosteson, R. Lacson, M.D. Schnall, D. Kontos, J.S. Haas, D.L. Weaver, W.E. Barlow, on behalf of the PROSPR consortium: Variation in mammographic breast density assessments among radiologists in clinical practice: Findings from a multicenter observational study Annals of Internal Medicine 165 (7): 457-464,2016.
L. Chen, S. Ray, B.M. Keller, S. Pertuz, E.S. McDonald, E.F. Conant, D. Kontos: The Impact of Acquisition Dose on Quantitative Breast Density Estimation with Digital Mammography: Results from ACRIN PA 4006 Radiology 280 (3): 693-700,2016.
A.M. McCarthy, B.M. Keller, L.M. Pantalone, M-K. Hsieh, M. Synnestvedt, E.F. Conant, K. Armstrong, D. Kontos: Racial differences in quantitative measures of area and volumetric breast density Journal of the National Cancer Institute (JNCI) 108 (10): djw104 doi: 10.1093/jnci/djw104,2016.
S. Pertuz, E. McDonald, S.P. Weinstein, E.F. Conant, D. Kontos: Fully-automated quantitative estimation of volumetric breast density from digital breast tomosynthesis images: Preliminary results and comparison with digital mammography and magnetic resonance imaging Radiology 279 (1): 65-74,2016.
B.M. Keller, J. Chen, D. Daye, E.F. Conant, D. Kontos: Preliminary evaluation of the publicly available Laboratory for Breast Radiodensity Assessment (LIBRA) software tool: Comparison of fully-automated area and volumetric density measures in a case-control study with digital mammography Breast Cancer Research 17 (1): 117; doi: 10.1186/s13058-015-0626-8.,2015.
S. Wu, S.P. Weinstein, M.J. Deleo, E.F. Conant, J. Chen, S.M. Domchek, D. Kontos: Quantitative assessment of Background Parenchymal Enhancement in breast MRI predicts response to Risk-Reducing Salpingo-Oophorectomy: Preliminary evaluation in a cohort of BRCA1/2 mutation carriers Breast Cancer Research 17 (67): doi: 10.1186/s13058-015-0577-0,2015.
AM. McCarthy, D. Kontos, M. Synnestvedt, K. Tan, D.F. Heitjan, M. Schnall, E.F. Conant: Screening Outcomes Following Implementation of Digital Breast Tomosynthesis in a General-Population Screening Program Journal of the National Cancer Institute (JNCI) 106 (11): dju316,2014.
A.B. Ashraf, D. Daye, S. Gavenonis, C. Mies, M. Feldman, M. Rosen, D. Kontos: Identification of intrinsic radio-phenotypes for breast cancer tumors: Preliminary associations with gene expression profiles Radiology 272 (2): 374-84,2014.
A. Ashraf, S. Gavenonis, D. Daye, C. Mies, M. Feldman, M.A. Rosen, and D. Kontos: A Multichannel Markov Random Field Framework for Tumor Segmentation with an Application to Classification of Gene Expression-based Breast Cancer Recurrence Risk IEEE Transactions on Medical Imaging 32 (4): 637-48,2013.
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