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Dennis Sprecher, MD

Dennis Sprecher, MD Non-Penn Medicine Provider

Dr. Sprecher is a private practice physician who is not employed by Penn Medicine.

Clinical Specialties


  • Medicine
    • Cardiology

Programs & Centers:

Board Certification:

  • Cardiovascular Disease, 1985
  • Internal Medicine, 1981

Clinical Expertise:

  • Cardiac Risk Reduction
  • Cardiology Risk Intervention
  • Cholesterol
  • Cholesterol and Lipid Disorders
  • Hypercholesterolemia
  • Hyperlipidemia
  • Hypertension
  • Lipid Disorders
  • Preventive Cardiology
  • Primary Care - Cardiac Risk Reduction
  • Primary Care - Cholesterol

Description of Clinical Expertise

Dr. Sprecher participates in the clinical activities of the Cardiac Risk Intervention Program (CRIP) at the Hospital of the University of Pennsylvania

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: Boston University School of Medicine
Residency: Michael Reese Hospital
Fellowship: Duke University Medical Center


American Association for the Advancement of Science, National American College of Physicians, National American Federation for Clinical Research, National American Heart Association, National American Society of Human Genetics, National National Institutes of Health, National None, International None, Local

Hospital Affiliation

Dr. Sprecher is a private practice physician who is not employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Dr. Sprecher is a recognized expert in the areas of lipoprotein metabolism, coronary heart disease and cardiac risk intervention. His studies have involved the influence of a PPAR delta agonist on cardiac tissue relative to heart failure. Using a PPAR ligand, he has challenged the efficiency of contractility when substrate utilization has switched to glucose versus fat in the failing myocardium. The underlying hypothesis is that returning substrate to more tricyclycerol-based energetics will be beneficial.

Academic Contact Info

709 Swedeland Road (UW 2301)

King Of Prussia, PA 19406
Phone: (610) 270-6007
Fax: (610) 270-4114
Patient appointments: 800-789-PENN (7366)

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