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Deepak M. Sampathu, MD, PHD

Deepak M. Sampathu, MD, PHD Physician

Assistant Professor of Clinical Radiology

Dr. Sampathu is employed by Penn Medicine.

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Clinical Specialties

Specialty:

  • Radiology

Programs & Centers:

Board Certification:

  • Diagnostic Radiology, 2012
  • Neuroradiology, 2014

Description of Clinical Expertise

Neuroradiology, Diagnostic Radiology, MRI, CT, Radiography, Image-guided lumbar puncture, Myelography

Practice Locations and Appointments

  • Penn Radiology Perelman

    Perelman Center for Advanced Medicine Atrium, Ground Floor 3400 Civic Center Boulevard Philadelphia, PA 19104 800-789-7366 (PENN)

    A facility of the Hospital of the University of Pennsylvania

  • Penn Radiology HUP

    Hospital of the University of Pennsylvania 1st Floor, Dulles Building 3400 Spruce Street Philadelphia, PA 19104 800-789-7366 (PENN)

    A facility of the Hospital of the University of Pennsylvania

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Amerihealth
  • NJ Medicaid
  • NJ Medicare
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Care
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: University of Pennsylvania School of Medicine
Residency: Penn Presbyterian Medical Center
Residency: Hospital of the University of Pennsylvania

Memberships

American Roentgen Ray Society, National American Society of Head and Neck Radiology, National American Society of Neuroradiology, National Radiological Society of North America, National

Hospital Affiliation

Dr. Sampathu is employed by Penn Medicine.

Hospital Privileges:

  • Chester County Hospital: Has privileges to treat patients in the hospital.
  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.

Research

Description of Research Expertise:

Pathobiology of Neurodegenerative Diseases, Cell and Molecular Biology

Selected Publications:

Neumann Manuela, Sampathu Deepak M, Kwong Linda K, Truax Adam C, Micsenyi Matthew C, Chou Thomas T, Bruce Jennifer, Schuck Theresa, Grossman Murray, Clark Christopher M, McCluskey Leo F, Miller Bruce L, Masliah Eliezer, Mackenzie Ian R, Feldman Howard, Feiden Wolfgang, Kretzschmar Hans A, Trojanowski John Q, Lee Virginia M-Y: Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 314 (5796): 130-3,2006.

Sampathu Deepak M, Neumann Manuela, Kwong Linda K, Chou Thomas T, Micsenyi Matthew, Truax Adam, Bruce Jennifer, Grossman Murray, Trojanowski John Q, Lee Virginia M-Y: Pathological heterogeneity of frontotemporal lobar degeneration with ubiquitin-positive inclusions delineated by ubiquitin immunohistochemistry and novel monoclonal antibodies. The American Journal of Pathology 169 (4): 1343-52,2006.

Meulener Marc C, Graves Charles L, Sampathu Deepak M, Armstrong-Gold Cecilia E, Bonini Nancy M, Giasson Benoit I: DJ-1 is present in a large molecular complex in human brain tissue and interacts with alpha-synuclein. Journal of Neurochemistry 93 (6): 1524-32,2005.

Pawlyk Aaron C, Giasson Benoit I, Sampathu Deepak M, Perez Francisco A, Lim Kah Leong, Dawson Valina L, Dawson Ted M, Palmiter Richard D, Trojanowski John Q, Lee Virginia M-Y: Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age. The Journal of Biological Chemistry 278 (48): 48120-8,2003.

Sampathu Deepak M, Giasson Benoit I, Pawlyk Aaron C, Trojanowski John Q, Lee Virginia M-Y: Ubiquitination of alpha-synuclein is not required for formation of pathological inclusions in alpha-synucleinopathies. The American Journal of Pathology 163 (1): 91-100,2003.

Giasson Benoit I, Sampathu Deepak M, Wilson Christina A, Vogelsberg-Ragaglia Vanessa, Mushynski Walter E, Lee Virginia M-Y: The environmental toxin arsenite induces tau hyperphosphorylation. Biochemistry 41 (51): 15376-87,2002.

Galvin J E, Nakamura M, McIntosh T K, Saatman K E, Sampathu D, Raghupathi R, Lee V M, Trojanowski J Q: Neurofilament-rich intraneuronal inclusions exacerbate neurodegenerative sequelae of brain trauma in NFH/LacZ transgenic mice. Experimental Neurology 165 (1): 77-89,2000.

Academic Contact Info

Department of Radiology
3400 Spruce Street

Philadelphia, PA 19104
Patient appointments: 800-789-7366 (PENN)