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Daniel N. Holena, MD

Daniel N. Holena, MD Surgeon

Assistant Professor of Surgery at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia

Dr. Holena is a Penn Medicine employed physician.

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  1. He or she is not employed by Penn Medicine.
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Clinical Specialties


  • Traumatology, Surgical Critical Care and Emergency Surgery

Programs & Centers:

Board Certification:

  • Surgery, 2007
  • Surgical Critical Care, 2008

Clinical Expertise:

  • Emergency General Surgery
  • Emergency Trauma
  • Surgical Critical Care

Description of Clinical Expertise

Dr. Daniel Holena is board certified in General Surgery and Surgical Critical Care. He received his General Surgery training at Cornell, and completed is fellowship in Trauma Surgery and Surgical Critical Care at the University of Pennsylvania. Dr. Holena specializes in the treatment of traumatic injury, emergency general surgery conditions, and surgical critical care. His research interests include outcomes after emergency general surgery and triage biomarkers in acute trauma.

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Cigna
  • Cigna HealthSpring
  • CVS Health
  • Devon Health Services (Americare)
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan

Education and Training

Medical School: SUNY Stony Brook School of Medicine
Residency: NewYork-Presbyterian/Columbia University Medical Center
Fellowship: Hospital of the University of Pennsylvania


American Association for the Surgery of Trauma, National American College of Surgeons, National American Medical Association, National Association for Academic Surgery, National Eastern Association for the Surgery of Trauma, National European Society for Trauma & Emergency Surgery, International Pennsylvania Medical Society, Local Society for Advancement of Violence and Injury Research, National Society of Critical Care Medicine, National Society of University Surgeons, National

Hospital Affiliation

Dr. Holena is a Penn Medicine employed physician.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Rittenhouse Long-Term Acute Care Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Dr. Holena's research interests encompass the study of quality of care after injury. He has a specific interest in the methodology used for risk-adjusting trauma morbidity, mortality, and failure to rescue.

Selected Publications:

Smith BP, Fick CE, Holena DN: Fractured Care and Outcomes After Injury: National Estimates of 30-day Hospital Readmissions and Mortality Annual Academic Surgical Congress. Las Vegas, NV. : 2017.

Sharoky CE, Kaufman EJ, Jacoby SF, Reilly PM, Holena DN: Police Transport of Bluntly Injured Trauma Patients in Philadelphia, 2006-2015. 12th Annual Academic Surgical Congress. Las Vegas, NV : 2017.

Kuo L, Frank B, Sharoky C, Holena DN: MRI Overuse? A critical Appraisal of a Statewide Trauma System Cervical Spine Management. 12th Annual Academic Surgical Congress. Las Vegas, NV : 2017.

DiSanto T, Reilly JP, Forker C, Christie JD, Holena DN, Lanken P, Shashaty M.: Modest Early Elevations in Creatine Kinase are Associated with Acute Kidney Injury after Trauma Critical Care Congress. Honolulu, Hawaii. : 2017.

Holena DN, Kauffman EJ, Delgado MK, Carr BG, Wiebe DJ, Christie JD, Reilly PM.: A Metric of Our Own: Failure to Rescue after Trauma. (In Submission) Journal of Trauma and Acute Care Surgery : 2017.

Carr BG, Bowman A, Wolff C, Mullen MT, Holena DN, Branas CC, Wiebe DJ: Disparities in Access To Trauma Care in the United States: A Population-Based Analysis. Injury : 2017.

Wiebe DJ, Holena DN, Delgado MK, Geiger J, McWilliams N, Carr BG.: The Pennsylvania Trauma Outcomes Study Risk-Adjusted Mortality Model: Results of a Statewide Benchmarking Program. The American Surgeon. : 2017.

Kauffman EJ, Earl-Royal E, Holena DN.: Failure to Rescue after Infectious Complications in a Statewide Trauma System. Surgical Infection : 2016.

Holena DN, Reilly PM, Jacoby SF: Towards a Broader View of Police Prehospital Transport. Journal of Trauma : 2016.

Kauffman EJ, Holena DN, Wiebe DJ, Carr BG: Lead Time Bias and Interhospital Transfer After Injury: Trauma Center Admission Vital Signs Underpredict Mortality in Transferred Trauma Patients. Journal of the American College of Surgeons : 2016.

Academic Contact Info

Division of Trauma, Surgical Critical Care & Emergency Surgery
Penn Presbyterian Medical Center
51 North 39th St., Suite 120

Philadelphia, PA 19104
Phone: (215) 662-7323
Fax: (215) 243-3221
Patient appointments: 800-789-PENN (7366)

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