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Daniel N. Holena, MD

Daniel N. Holena, MD Physician

Associate Professor of Surgery at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia Associate Professor of Epidemiology in Biostatistics and Epidemiology

Dr. Holena is employed by Penn Medicine.

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Clinical Specialties


  • Trauma Surgery

Programs & Centers:

Board Certification:

  • Surgery, 2007
  • Surgical Critical Care, 2008

Clinical Expertise:

  • Emergency General Surgery
  • Emergency Trauma
  • Surgical Critical Care

Practice Locations and Appointments

Insurance Accepted

  • Aetna US Healthcare
  • Amerihealth Caritas
  • Amerihealth Caritas Medicare
  • Cigna
  • Cigna HealthSpring
  • Clover Health Plan
  • CVS Health
  • Devon Health Services (Americare)
  • eLAP Services
  • Gateway Health Plan
  • Geisinger Health Plan
  • HealthAmerica / HealthAssurance, a Coventry Plan
  • HealthPartners
  • HealthPartners Medicare
  • HealthSmart
  • Highmark Blue Shield
  • Homestead Smart Health Plans
  • Horizon Blue Cross Blue Shield of New Jersey
  • Humana / Choicecare
  • Independence Blue Cross (Keystone East)
  • Intergroup
  • Keystone First
  • Keystone First Medicare
  • Multiplan
  • NJ Medicaid
  • NJ Qualcare
  • Oxford Health Plan
  • PA Health and Wellness (Centene) Medicare
  • PA Medicaid
  • PA Medicare
  • Preferred Health Care/LGH
  • Provider Partners Health Plan
  • Rail Road Medicare / Palmetto GBA
  • Remedy Partners at Penn Medicine
  • Tricare
  • United Healthcare
  • UnitedHealthcare Community Plan
  • US Family Health Plan
  • Veterans Choice Program

Education and Training

Medical School: State University of New York at Stony Brook
Residency: NewYork-Presbyterian/Columbia University Medical Center
Fellowship: Hospital of the University of Pennsylvania


American Association for the Surgery of Trauma, National American College of Surgeons, National American College of Surgeons, Philadelphia Chapter, National Association for Academic Surgery, National Eastern Association for the Surgery of Trauma, National European Society for Trauma & Emergency Surgery, International Pennsylvania Medical Society, Local Pennsylvania Trauma Systems Foundation, Local Society for Advancement of Violence and Injury Research, National Society of Critical Care Medicine, National Society of University Surgeons, National

Hospital Affiliation

Dr. Holena is employed by Penn Medicine.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Medicine Rittenhouse Long-Term Acute Care Hospital: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Description of Research Expertise:

Dr. Holena's research interests encompass the study of quality of care after injury. He has a specific interest in the methodology used for risk-adjusting trauma morbidity, mortality, and failure to rescue.

Selected Publications:

Hatchimonji J, Kaufman E, Sharoky C, Ma L, Garcia A, Holena D: Failure to Rescue in Surgical Patients: A Review for Acute Care Surgeons Journal of Trauma : 2019 (in press).

Shashaty M, Reilly J, Faust H, Forker C, Ittner C, Zhang P, Hotz M, Fitzgerald D, Yang W, Anderson B, Holena D, Lanken P, Christie J, Meyer N, Mangalmurti N: Plasma receptor interacting protein kinase-3 levels are associated with acute respiratory distress syndrome in sepsis and trauma: a cohort study Critical Care : 2019 (in press).

Holena D: The Impact of Interhospital Transfer on Mortality Benchmarking at Level III and IV Trauma Centers: A Step Towards Shared Mortality Attribution in a Statewide System American Association for the Surgery of Trauma and Clinical Congress of Acute Care Surgery, Dallas, Texas : 2019.

Kaufman E, Holena D: Outcomes after abdominal surgery for trauma in obese patients Shock Society Meeting, Coronado, CA : 2019.

Hatchimonji J, Holena DN, Kaufman E, Garcia AE, Sharoky CE: A contemporary analysis of delayed diagnoses after traumatic injury: The role of operative therapy Annual Meeting of the Southwestern Surgical Congress, Huntington Beach, CA : 2019.

Tung L, Seamon M, Holena DN, Kaplan L, Reilly PM, Niels M: Does Contemporary General Surgery Training Include Sufficient Operative Trauma Experience? Association of Program Directors in Surgery Annual Meeting : 2019.

Sharoky CE, Martin ND, Smith BP, Pascual JL, Kaplan LJ, Reilly PM, Holena DN: The location and timing of failure to rescue events across a statewide trauma system Journal of Surgical Research 2019 (235): 529-35,2019.

Asfaw SH, Martin ND, Seamon MJ, Pascual JL, Reilly PM, Holena DN: Is it cool to cool post cardiac arrest trauma patients? The American Surgeon: Brief Reports 85 (3): 2019.

Moore SA, Maduka R, Reilly PM, Morris JC, Seamon MJ, Holena DN, Kaplan LJ, Martin ND: Training Disparities & Expectations of Our Future Workforce: A Survey of Trauma Fellowship Candidates 14th Annual Academic Surgical Congress, Houston, TX : 2019.

Vasquez C; Forker C; Dunn T; Meyer N; Holena D; Lanken P; Reilly JP; Feldman H; Christie JD; Shashaty M : Plasma adipokine levels are associated with acute kidney injury after severe trauma Society of Critical Care Medicine Annual Meeting, San Diego, CA : 2019.

Academic Contact Info

Division of Trauma, Surgical Critical Care & Emergency Surgery
Penn Presbyterian Medical Center
51 North 39th St., Suite 120

Philadelphia , PA 19104
Phone: (215) 662-7323
Patient appointments: 800-789-7366 (PENN)

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