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Christopher E. Mascio, MD

Christopher E. Mascio, MD Children's Hospital of Philadelphia Provider

Associate Professor of Clinical Surgery

Dr. Mascio is employed by the Children's Hospital of Philadelphia.

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Clinical Specialties


  • Cardiac Surgery

Programs & Centers:

  • Adult Congenital Heart Disease Program

Board Certification:

  • Congenital Cardiac Surgery, 2010
  • Thoracic and Cardiac Surgery, 2006

Clinical Expertise:

  • Aortic Coarctation
  • Aortic Stenosis
  • Aortic Valve Procedures
  • Atrial Septal Defect (ASD)
  • Cardiac Rehabilitation
  • Congenital Heart Disease in Adult
  • Coronary Artery Bypass Graft Surgery (CABG)
  • Cyanotic Heart Disease
  • Esophageal Disorders
  • Heart Transplantation
  • Left Ventricular Assist Device
  • Marfan Syndrome
  • Mediastinal Disorders
  • Mediastinal Tumors
  • Minimally Invasive Cardiac Surgery
  • Minimally Invasive Mitral Valve Surgery
  • Mitral Stenosis
  • Mitral Valve Regurgitation
  • Mitral Valve Repair
  • Mitral Valve Replacement
  • Patent Foramen Ovale (PFO)
  • Pulmonary Valve Stenosis (PVS)
  • Robotic Cardiac Surgery
  • Septal Myectomy
  • Transcatheter Aortic Valve Replacement (TAVR)
  • Tricuspid Regurgitation
  • Truncus Arteriosus
  • Ventricular Septal Defect (VSD)
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Practice Locations and Appointments

Education and Training

Medical School: Loyola University Medical Center
Residency: Loyola University Medical Center
Fellowship: University of Iowa Hospitals and Clinics
Fellowship: Children's Hospital of Philadelphia


American College of Surgeons, National American Heart Association, National Congenital Heart Surgeons' Society, National Eastern Cardiothoracic Surgical Society, National International Society for Pediatric Mechanical Cardiopulmonary Support, International Society of Thoracic Surgeons Patient Safety Workforce, National Society of Thoracic Surgeons, National Southeastern Surgical Congress, Local Southern Thoracic Surgical Association, Local

Hospital Affiliation

Dr. Mascio is employed by the Children's Hospital of Philadelphia.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Selected Publications:

Wu SJ, Downing T, Mascio C, Gillespie MJ, Dori Y, Rome JJ, Glatz AC: Reintervention burden and vessel growth after surgical reimplantation of a pulmonary artery during childhood Pediatric Cardiology 39 (2): 390-397,2018.

Mejia EJ, O'Connor MJ, Lin KY, Song L, Griffis H, Mascio CE, Shamszad P, Donoghue A, Ravishankar C, Shaddy RE, Rossano JW: Characteristics and outcomes of pediatric heart failure-related emergency department visits in the United States: A population-based study Journal of Pediatrics 193 : 114-118.e3,2018.

Nandi D, Miller KD, Bober CM, Rosenthal TM, Montenegro LM, Rossano JW, Gaynor JW, Mascio CE: Systemic atrioventricular valve excision and ventricular assist devices in pediatric patients Annals of Thoracic Surgery 105 (1): 170-174,2018.

Mascio CE, Austin EH: Coarctation of aorta: Repair of coarctation and arch interruption Operative Cardiac Surgery, 6th Edition : 2017 (in press).

Scanlan AB, Nguyen AV, Ilina A, Lasso A, Cripe L, Jegatheeswaran A, Silvestro E, McGowan FX, Mascio CE, Fuller S, Spray TL, Cohen MS, Fichtinger G, Jolley MA: Comparison of 3D echocardiogram-derived 3D printed valve models to molded models for simulated repair of pediatric atrioventricular valves Pediatric Cardiology : 2017 (Epub).

Glatz AC, Petit CJ, Goldstein BH, Kelleman MS, McCracken CE, McDonnell A, Buckey T, Mascio CE, Shashidharan S, Ligon RA, Ao J, Whiteside W, Wallen WJ, Metcalf CM, Aggarwal V, Agrawal H, Qureshi AM: A comparison between patent ductus arteriosus stent and modified Blalock-Taussig shunt as palliation for infants with ductal-dependent pulmonary blood flow: Insights from the congenital catheterization research collaborative Circulation : 2017 (Epub).

Mascio CE, Malankar DP, Rome JJ: HeartWare ventricular assist device as a bridge-to-transplant in a small boy with complicated Kawasaki Disease ASAIO Journal : 2017 (Epub).

Keeshan BC, O'Connor MJ, Lin KY, Monos D, Lind C, Mascio CE, Rame JE, Spray TL, Shaddy RE, Rossano JW: Value of a flow cytometry cross-match in the setting of a negative complement-dependent cytotoxicity cross-match in heart transplant recipients Clinical Transplantation 31 (10): 2017.

Herrmann JL, Irons ML, Mascio CE, Rychik J, Spray TL, Gaynor JW, Pogoriler JE: Congenital pulmonary lymphangiectasia and early mortality after stage 1 reconstruction procedures Cardiology in the Young 27 (7): 1356-1360,2017.

Wittlieb-Weber CA, Rossano JW, Weber DR, Lin KY, Ravishankar C, Mascio CE, Shaddy RE, O'Connor MJ: Emergency department utilization in pediatric heart transplant recipients Pediatric Transplantation 21 (4): 2017.

Academic Contact Info

Division of Cardiothoracic Surgery
Children’s Hospital of Philadelphia
34th Street & Civic Center Boulevard
Main Bldg. 12NW10

Philadelphia, PA 19104
Phone: (215) 590-2708
Patient appointments: 800-789-7366 (PENN)