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Christopher E. Mascio, MD

Christopher E. Mascio, MD Children's Hospital of Philadelphia Provider

Associate Professor of Clinical Surgery

Dr. Mascio is employed by the Children's Hospital of Philadelphia.

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Clinical Specialties


  • Cardiac Surgery

Programs & Centers:

  • Adult Congenital Heart Disease Program

Board Certification:

  • Congenital Cardiac Surgery, 2010
  • Thoracic and Cardiac Surgery, 2006

Clinical Expertise:

  • Acquired Heart Block
  • Adult Congenital Heart Disease in Pregnancy
  • Adventitial Cystic Disease
  • Aneurysm Repair Surgery
  • Anomalies of Pulmonary Circulation
  • Anomalies of the Aorta
  • Anomalous Coronary Artery
  • Anomalous Pulmonary Artery
  • Anomalous Pulmonary Venous Return
  • Aortic Angioplasty
  • Aortic Arch Aneurysm
  • Aortic Coarctation
  • Aortic Root Replacement
  • Aortic Stenosis
  • Aortic Ulcer
  • Aortic Valve Procedures
  • Aortic Valve Sclerosis
  • Aortic Valve Surgery
  • Aortopulmonary Window
  • Atrial Arrhythmia
  • Atrial Isomerism
  • Atrial Septal Defect (ASD)
  • Atrial Septal Defect Repair
  • Atrioventricular Canal Defect
  • Atrioventricular Septal Defect
  • Balloon Catheter
  • Bloodless Cardiac Surgery
  • Cardiac Implant Closure Devices
  • Cardiac Rehabilitation
  • Chylothorax
  • Circulatory Assist Devices
  • Collateral Vessel Closure
  • Combined Heart Lung Transplant
  • Common Aortopulmonary Trunk
  • Congenital Anomaly of Great Veins
  • Congenital Anomaly of the Aortic Arch
  • Congenital Anomaly of the Coronary Artery
  • Congenital Aortic Valve Disease
  • Congenital Atresia of the Pulmonary Valve
  • Congenital Heart Disease in Adult
  • Congenital Insufficiency of the Aortic Valve
  • Congenital Mitral Valve Regurgitation
  • Congenital Pulmonary Valve Atresia
  • Congenital Stenosis of the Aortic Valve
  • Congenital Stenosis of the Mitral Valve
  • Congenital Stenosis of the Pulmonary Valve
  • Congenital Subaortic Stenosis
  • Congenital Tricuspid Stenosis
  • Congenitally Corrected Transposition of the Great Arteries
  • Convergent Procedure
  • Coronary Artery Bypass Graft Surgery (CABG)
  • Cyanotic Heart Disease
  • Double Aortic Arch
  • Double Outlet Left Ventricle
  • Double Outlet Right Ventricle
  • Ebstein Anomaly
  • Embolectomy
  • Endocardial Cushion Defect
  • Enhanced External Counterpulsation
  • Epicardial Lead Placement
  • Esophageal Disorders
  • Extracorporeal Membrane Oxygenation
  • Heart Block
  • Heart Transplant Rejection
  • Heart Transplantation
  • Hemitruncus
  • Hypoplastic Left Heart Syndrome
  • Hypoplastic Right Ventricle
  • Idiopathic Hypertrophic Subaortic Stenosis
  • Impella Insertion
  • Impella Management
  • Infiltrative Disorders of the Heart
  • Infundibular Pulmonic Stenosis
  • Interrupted Aortic Arch
  • Intra-Aortic Balloon Pump
  • Intracardiac Foreign Body
  • Intravascular Foreign Body
  • Ischemic Cardiomyopathy
  • Junctional Arrhythmia
  • Konno Procedure
  • Left Atrial Appendage Closure
  • Left Atrial Appendage Occlusion
  • Left Ventricular Assist Device
  • Levocardia
  • Loeys-Dietz Syndrome
  • LV to Aorta Tunnel
  • Malformation of the Heart
  • Malposition of the Heart and Cardiac Apex
  • Marfan Syndrome
  • Maternal Valvular Disease
  • Mechanical Circulatory Support
  • Median Sternotomy
  • Mediastinal Disease
  • Mediastinal Disorders
  • Mediastinal Tumors
  • Mediastinitis
  • Mesocardia
  • Minimally Invasive Aortic Valve Replacement
  • Minimally Invasive Cardiac Surgery
  • Minimally Invasive Closure of Atrial Septal Defect
  • Minimally Invasive Coronary Bypass Surgery
  • Minimally Invasive Mitral Valve Surgery
  • Minimally Invasive Ventricular Septal Defect Closure
  • Mitral Regurgitation
  • Mitral Stenosis
  • Mitral Valve Regurgitation
  • Mitral Valve Repair
  • Mitral Valve Replacement
  • Myocardial Bridge
  • Off-Pump Coronary Artery Bypass
  • Overriding Aorta
  • Paravalvular Leak Repair
  • Partial Anomalous Pulmonary Venous Connection
  • Patent Ductus Arteriosus
  • Patent Foramen Ovale (PFO)
  • Patent Foramen Ovale Closure
  • Percutaneous Atrial Septal Defect Closure
  • Percutaneous Valvuloplasty
  • Percutaneous Ventricular Septal Defect Closure
  • Pericardial Disease
  • Pericardial Effusion
  • Pericardiocentesis
  • Pericardiotomy
  • Peripheral Pulmonary Stenosis
  • Persistant Fetal Circulation
  • Persistent Ostium Primum
  • Prosthetic Heart Valves
  • Prosthetic Valve Failure
  • Pulmonary and Cardiac Rehabilitation
  • Pulmonary Arteriovenous Malformation
  • Pulmonary Artery Aneurysm
  • Pulmonary Artery Coarctation and Atresia
  • Pulmonary Artery Sling
  • Pulmonary Artery Stenosis
  • Pulmonary AV Fistula
  • Pulmonary Clearance for Surgery
  • Pulmonary Thromboendarterectomy
  • Pulmonary Valve Disorders
  • Pulmonary Valve Insufficiency
  • Pulmonary Valve Stenosis (PVS)
  • Pulmonary Vein Stenosis
  • Pulmonary Venous Anomalies
  • Pulmonic Valve Replacement
  • Reoperative Cardiac Surgery
  • Replacement of Heart Valve
  • Rheolytic Thrombectomy
  • Rheumatic Mitral Stenosis
  • Rib Tumor
  • Right Ventricular Outlet Tract Obstruction
  • Robotic Cardiac Surgery
  • Rupture of Papillary Muscle
  • Scimitar Syndrome
  • Septal Myectomy
  • Shone's Complex
  • Single Ventricle Defects
  • Situs Inversus
  • Sternal Tumor
  • Surgical Ablation of Atrial Fibrillation
  • Systemic Venous Anomalies
  • Tetralogy of Fallot
  • Thoracic Aneurysm Repair
  • Thoracic Endovascular Aortic Repair
  • Thoracoabdominal Aneurysm
  • Thrombectomy
  • Total Endoscopic Coronary Artery Bypass Grafting
  • Transcatheter Aortic Valve Replacement (TAVR)
  • Transcatheter Mitral Valve Repair
  • Transcatheter Pulmonary Valve Replacement
  • Transcatheter Tricuspid Valve Replacement
  • Transposition of the Great Vessels
  • Tricuspid Atresia
  • Tricuspid Regurgitation
  • Tricuspid Stenosis
  • Tricuspid Valve Disease
  • Tricuspid Valve Repair
  • Truncus Arteriosus
  • Truncus Arteriosus Communis
  • Tube Pericardiostomy
  • Valve-Sparing Surgery
  • Valvuloplasty
  • Vascular Ring
  • Ventricular Aneurysm
  • Ventricular Arrhythmia
  • Ventricular Septal Defect (VSD)
  • Ventricular Septal Defect Repair
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Practice Locations and Appointments

Education and Training

Medical School: Loyola University Medical Center
Residency: Loyola University Medical Center
Fellowship: University of Iowa Hospitals and Clinics
Fellowship: Children's Hospital of Philadelphia


American College of Surgeons, National American Heart Association, National Congenital Heart Surgeons' Society, National Eastern Cardiothoracic Surgical Society, National International Society for Pediatric Mechanical Cardiopulmonary Support, International Society of Thoracic Surgeons Patient Safety Workforce, National Society of Thoracic Surgeons, National Southeastern Surgical Congress, Local Southern Thoracic Surgical Association, Local

Hospital Affiliation

Dr. Mascio is employed by the Children's Hospital of Philadelphia.

Hospital Privileges:

  • Hospital of the University of Pennsylvania: Has privileges to treat patients in the hospital.
  • Penn Presbyterian Medical Center: Has privileges to treat patients in the hospital.
  • Pennsylvania Hospital: Has privileges to treat patients in the hospital.


Selected Publications:

Wu SJ, Downing T, Mascio C, Gillespie MJ, Dori Y, Rome JJ, Glatz AC: Reintervention burden and vessel growth after surgical reimplantation of a pulmonary artery during childhood Pediatric Cardiology 39 (2): 390-397,2018.

Mejia EJ, O'Connor MJ, Lin KY, Song L, Griffis H, Mascio CE, Shamszad P, Donoghue A, Ravishankar C, Shaddy RE, Rossano JW: Characteristics and outcomes of pediatric heart failure-related emergency department visits in the United States: A population-based study Journal of Pediatrics 193 : 114-118.e3,2018.

Nandi D, Miller KD, Bober CM, Rosenthal TM, Montenegro LM, Rossano JW, Gaynor JW, Mascio CE: Systemic atrioventricular valve excision and ventricular assist devices in pediatric patients Annals of Thoracic Surgery 105 (1): 170-174,2018.

Mascio CE, Austin EH: Coarctation of aorta: Repair of coarctation and arch interruption Operative Cardiac Surgery, 6th Edition : 2017 (in press).

Scanlan AB, Nguyen AV, Ilina A, Lasso A, Cripe L, Jegatheeswaran A, Silvestro E, McGowan FX, Mascio CE, Fuller S, Spray TL, Cohen MS, Fichtinger G, Jolley MA: Comparison of 3D echocardiogram-derived 3D printed valve models to molded models for simulated repair of pediatric atrioventricular valves Pediatric Cardiology : 2017 (Epub).

Glatz AC, Petit CJ, Goldstein BH, Kelleman MS, McCracken CE, McDonnell A, Buckey T, Mascio CE, Shashidharan S, Ligon RA, Ao J, Whiteside W, Wallen WJ, Metcalf CM, Aggarwal V, Agrawal H, Qureshi AM: A comparison between patent ductus arteriosus stent and modified Blalock-Taussig shunt as palliation for infants with ductal-dependent pulmonary blood flow: Insights from the congenital catheterization research collaborative Circulation : 2017 (Epub).

Mascio CE, Malankar DP, Rome JJ: HeartWare ventricular assist device as a bridge-to-transplant in a small boy with complicated Kawasaki Disease ASAIO Journal : 2017 (Epub).

Keeshan BC, O'Connor MJ, Lin KY, Monos D, Lind C, Mascio CE, Rame JE, Spray TL, Shaddy RE, Rossano JW: Value of a flow cytometry cross-match in the setting of a negative complement-dependent cytotoxicity cross-match in heart transplant recipients Clinical Transplantation 31 (10): 2017.

Herrmann JL, Irons ML, Mascio CE, Rychik J, Spray TL, Gaynor JW, Pogoriler JE: Congenital pulmonary lymphangiectasia and early mortality after stage 1 reconstruction procedures Cardiology in the Young 27 (7): 1356-1360,2017.

Wittlieb-Weber CA, Rossano JW, Weber DR, Lin KY, Ravishankar C, Mascio CE, Shaddy RE, O'Connor MJ: Emergency department utilization in pediatric heart transplant recipients Pediatric Transplantation 21 (4): 2017.

Academic Contact Info

Division of Cardiothoracic Surgery
Children’s Hospital of Philadelphia
34th Street & Civic Center Boulevard
Main Bldg. 12NW10

Philadelphia, PA 19104
Phone: (215) 590-2708
Patient appointments: 800-789-7366 (PENN)