PHILADELPHIA -- As many as 70% of certain cases of healthcare-acquired infections may be preventable with current evidence-based strategies according to a new study by Craig A. Umscheid, MD, MSCE, Assistant Professor of Medicine and Epidemiology and Director of the Center for Evidence-based Practice at the University of Pennsylvania. Healthcare-acquired infections are infections that occur during a hospitalization and that are not present prior to hospital admission.
Using estimates from national reports and published studies related to healthcare-acquired infections, the study suggests that if best practices in infection control were applied at all US hospitals, reducing the number of cases of catheter-associated bloodstream infections could save as many as 5,520-20,239 lives annually; for ventilator-associated pneumonia, 13,667- 19,782 lives annually; for catheter-associated urinary tract infections, 2,225-9,031 lives annually; and for surgical site infections, 2,133-4,431 lives annually.
The study by Umscheid and five Penn colleagues is published in February’s issue of Infection Control and Hospital Epidemiology.
Examples of current prevention strategies include clinician education, hand hygiene, maximum sterile barrier precautions during catheter insertion, chlorhexidine disinfection of catheter and surgical sites, prompt removal of unnecessary catheters, good blood sugar control in the surgical setting, and appropriate use of antibiotics.
Reducing hospital acquired infections also saves money. Based on the studies examined, preventable cases of catheter-associated bloodstream infections are likely to have the highest associated costs, ranging anywhere from $960 million to $18.2 billion annually. The hospital costs of preventable ventilator-associated pneumonia are estimated to be $2.19 billion to $3.17 billion annually. Costs of preventable catheter-associated urinary tract infections are estimated to be $115 million to $1.82 billion annually, and the costs of preventable surgical site infections are estimated to be $166 million to $345 million annually.
Umscheid concluded, “Given the limitations of the data used in this study and the resulting uncertainty in our estimates, it is our hope that this study guides future research to accurately measure the impact of strategies to reduce healthcare-acquired infections, as well as the incremental costs of these infections.”
Penn Medicine is one of the world's leading academic medical centers, dedicated to the related missions of medical education, biomedical research, and excellence in patient care. Penn Medicine consists of the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania (founded in 1765 as the nation's first medical school) and the University of Pennsylvania Health System, which together form a $5.3 billion enterprise.
The Perelman School of Medicine has been ranked among the top five medical schools in the United States for the past 18 years, according to U.S. News & World Report's survey of research-oriented medical schools. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $373 million awarded in the 2015 fiscal year.
The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania and Penn Presbyterian Medical Center -- which are recognized as one of the nation's top "Honor Roll" hospitals by U.S. News & World Report -- Chester County Hospital; Lancaster General Health; Penn Wissahickon Hospice; and Pennsylvania Hospital -- the nation's first hospital, founded in 1751. Additional affiliated inpatient care facilities and services throughout the Philadelphia region include Chestnut Hill Hospital and Good Shepherd Penn Partners, a partnership between Good Shepherd Rehabilitation Network and Penn Medicine.
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