Oxford Foundation Commits
Gift to Islet Isolation Facility
. Philadelphia - April
3, 2003 - The Juvenile Diabetes Research Foundation
International (JDRF) today received a major gift of
$1 million from the Oxford Foundation to support critical
research at the JDRF - Oxford Foundation Islet Isolation
Facility at the University of Pennsylvania.
The donation by the Oxford Foundation
and the Ware Family will enhance the research at the
JDRF - W.W. Smith Charitable Trust Center of Islet Transplantation
by using state-of-the art techniques in isolating and
preparing pancreatic islets for transplant.
"We at JDRF are extremely honored by the
Oxford Foundation's decision to partner with us in support
of our mission to find a cure for juvenile diabetes.
We are excited about the advances in islet transplantation
here and at 11 other JDRF funded research centers across
North America and we are constantly seeking new ways
to fund this critical research ," stated Peter Van Etten,
President and CEO of JDRF.
Islet isolation is a delicate and complex
process. The islet isolation laboratory headed by transplant
surgeon, James F. Markmann, MD, PhD, will standardize
the process of obtaining and preparing islets by developing
criteria to determine their quality and viability when
transplanted. The work of the laboratory will maximize
the availability of high quality islets and is essential
to the success of islet transplantation conducted by
Ali Naji, MD, PhD, and Director of the JDRF-W.W. Smith
Charitable Trust Center for Islet Transplantation.
"We are impressed by the commitment of
the Juvenile Diabetes Research Foundation in advancing
diabetes research and are encouraged by the progress
made in islet transplantation here at the University
of Pennsylvania and other institutions. The Oxford Foundation
and the Ware family are pleased to support this Islet
Isolation Facility with the hope that initiatives made
here will move us a step closer to a cure for juvenile
diabetes," said Paul W. Ware, President, of the Oxford
Recent advances in islet transplantation
have created a surge in the research efforts to restore
normal blood sugar levels in people with juvenile diabetes.
To date, over 150 patients have received islet transplants;
some have been successful with very near normal blood
glucose profiles. However, two challenges remain: the
shortage of islet supply and the need for tolerance
induction - getting the immune system to accept transplants
without the use of toxic antirejection drugs.
"The commitment demonstrated by the Oxford
Foundation to the JDRF - Oxford Foundation Islet Isolation
Facility at the University of Pennsylvania is truly
visionary, " states Dr. Arthur Rubenstein, Executive
Vice President of the University of Pennsylvania for
the Health System and Dean of the School of Medicine.
" We at Penn are elated by the opportunity to partner
with the Foundation and the JDRF in taking this important
step in our continuing quest to find a cure for juvenile
The Oxford Foundation is a private foundation
of the Ware family, which promotes excellence in health,
human services, education, early childhood development,
preservation, arts and culture, and public policy planning.
JDRF, the leading charitable funder and
advocate of juvenile (type 1) diabetes research worldwide,
was founded in 1970 by the parents of children with
juvenile diabetes - a disease which strikes children
suddenly, makes them insulin-dependent for life, and
carries the constant threat of devastating complications.
Since inception, JDRF has provided more than $600 million
in direct funding to diabetes research. In a typical
year, 85 percent of JDRF's expenditures directly support
research and research-related education. JDRF's mission
is constant: to find a cure for diabetes and its complications
through the support of research. For more information,
visit the JDRF web site at www.jdrf.org or call 800-533-CURE.
PENN Medicine is a $2.2 billion
enterprise dedicated to the related missions of medical
education, biomedical research, and quality patient
care. PENN Medicine consists of the University of Pennsylvania
School of Medicine (founded in 1765 as the nation's
first medical school) and the University of Pennsylvania
Health System (created in 1993 as the nation's first
integrated academic health system). Today, Penn's School
of Medicine is ranked #4 in the nation in U.S. News
& World Report's most recent ranking of top research-oriented
medical schools; and ranked #2 in the nation for receipt
of NIH research funds. It supports 1400-fulltime faculty
and 700 students, is recognized worldwide for its superior
education and training of the next generation of physician/scientists
and leaders of academic medicine. Penn's Health System
consists of four wholly-owned hospitals (including its
flagship Hospital of the University of Pennsylvania,
rated one of the nation's top "Honor Roll" hospitals
by U.S. News & World Report); a faculty practice plan;
a primary-care provider network; three multispecialty
satellite facilities; and home healthcare, hospice and
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Penn Medicine is one of the world's leading academic medical centers, dedicated to the related missions of medical education, biomedical research, and excellence in patient care. Penn Medicine consists of the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania (founded in 1765 as the nation's first medical school) and the University of Pennsylvania Health System, which together form a $5.3 billion enterprise.
The Perelman School of Medicine has been ranked among the top five medical schools in the United States for the past 18 years, according to U.S. News & World Report's survey of research-oriented medical schools. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $373 million awarded in the 2015 fiscal year.
The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania and Penn Presbyterian Medical Center -- which are recognized as one of the nation's top "Honor Roll" hospitals by U.S. News & World Report -- Chester County Hospital; Lancaster General Health; Penn Wissahickon Hospice; and Pennsylvania Hospital -- the nation's first hospital, founded in 1751. Additional affiliated inpatient care facilities and services throughout the Philadelphia region include Chestnut Hill Hospital and Good Shepherd Penn Partners, a partnership between Good Shepherd Rehabilitation Network and Penn Medicine.
Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2015, Penn Medicine provided $253.3 million to benefit our community.