(Philadelphia, PA) - John B. Weigele, PhD, MD, has been appointed Assistant Professor in the Department of Radiology, at the University of Pennsylvania School of Medicine.

Dr. Weigele earned his PhD in Biochemistry from the University of Pennsylvania and his MD from the University of Pennsylvania School of Medicine in 1982. He completed his internship at Presbyterian Medical Center and residency in Radiology at the Hospital of the University of Pennsylvania (HUP). Dr. Weigele held fellowships at several medical institutions, including a fellowship in Vascular and Interventional Radiology at State University of New York (SUNY) Health Science Center, Syracuse; a fellowship in Body MR Imaging at HUP; a fellowship in Neuroradiology at Georgetown University Medical Center, the National Institutes of Health, and Johns Hopkins Hospital; and, a fellowship in Interventional Neuroradiology at the University of Iowa Hospital and Clinics.

His research focuses on developing new ways to treat blood vessel abnormalities of the brain and spinal cord, and evaluating percutaneous vertebroplasty, a new method to treat painful vertebral (back) compression fractures.

Dr. Weigele is a senior member of the American Society of Neuroradiology and a member of the American College of Radiology, American Roentgen Ray Society, American Medical Association, Radiologic Society of North America, American Heart Association-Cardiovascular Council, and the American Society of Interventional and Therapeutic Neuroradiology, among others. He has been published in peer-reviewed publications and book chapters including the Journal of Neurosurgery, Radiology, Magnetic Resonance Quarterly, Proceedings of the National Academy of Sciences, Neurosurgery, Journal of Neurochemistry, Journal of Physiology (London), Advances in Neurology and Essentials in Musculoskeletal Imaging.


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Penn Medicine is one of the world’s leading academic medical centers, dedicated to the related missions of medical education, biomedical research, excellence in patient care, and community service. The organization consists of the University of Pennsylvania Health System and Penn’s Raymond and Ruth Perelman School of Medicine, founded in 1765 as the nation’s first medical school.

The Perelman School of Medicine is consistently among the nation's top recipients of funding from the National Institutes of Health, with $550 million awarded in the 2022 fiscal year. Home to a proud history of “firsts” in medicine, Penn Medicine teams have pioneered discoveries and innovations that have shaped modern medicine, including recent breakthroughs such as CAR T cell therapy for cancer and the mRNA technology used in COVID-19 vaccines.

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