Pregnancy loss evaluations help couples understand the cause of their loss and can, therefore, offer a solution for how to start a family.

Causes of a Pregnancy Loss

Pregnancy loss, particularly early miscarriage, is a common problem that affects many women and their partners. Losing a pregnancy is extremely difficult for the expectant parents, and even early losses cause frustration and grief. Many couples are anxious to understand why a miscarriage has occurred and may be hesitant to pursue another pregnancy until they know more about the cause of their loss.

While some miscarriages are caused by genetic or chromosomal abnormalities, other factors can contribute to repeated pregnancy loss. Testing can uncover problems within the uterus or cervix, as well as certain hormonal and immunological factors that could contribute to pregnancy loss.

Couples may benefit from a pregnancy loss evaluation if they:

  • Have suffered three or more miscarriages
  • Have had two miscarriages and difficulty achieving pregnancy
  • Have a family history of repeated pregnancy loss
  • Have a maternal history of autoimmune disorders, thrombosis, lupus or antiphospholipid antibodies
Fortunately, careful evaluation often helps alleviate concerns about attempting future pregnancies. In many cases following evaluation, the monitoring of future pregnancies can lead to the birth of a healthy baby.

Penn is a leading research center in the field of infertility and human reproduction. Based your clinical history and the stage of pregnancy at which you have experienced pregnancy losses, your obstetrician or gynecologist may decide whether referral to our genetics program, infertility program or a high-risk obstetrician would be helpful to determine the cause of your losses and treatment options.

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