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Hospital of the University of Pennsylvania Pharmacy Residency

Program Purpose Statement

PGY2 pharmacy residency programs build on Doctor of Pharmacy (PharmD) education and PGY1 pharmacy residency programs to contribute to the development of clinical pharmacists in specialized areas of practice. PGY2 residencies provide residents with opportunities to function independently as practitioners by conceptualizing and integrating accumulated experience and knowledge and incorporating both into the provision of patient care or other advanced practice settings. Residents who successfully complete an accredited PGY2 pharmacy residency are prepared for advanced patient care, academic, or other specialized positions, along with board certification, if available.

The PGY2 Solid Organ Transplant Pharmacy Residency Program at the Hospital of the University of Pennsylvania (HUP) is designed to develop PGY1 Pharmacy Residency graduates into clinical specialists who can successfully manage all aspects of pharmaceutical care for adult solid organ transplant donors and recipients. Graduates of this rigorous program will be well equipped to care for solid organ transplant patients across all phases of care, including candidate evaluation, the inpatient transplant admission, post-transplant ambulatory care, and hospital readmission.

Program Overview

The Solid Organ Transplant Pharmacy Residency Program at the Hospital of the University of Pennsylvania has been in existence since 2007. This residency is a full time practice commitment and is 12 months in duration. The program offers comprehensive learning experiences in all major solid organs, including kidney/pancreas, liver, heart, and lung transplantation, as well as transplant infectious disease. Residents will serve as an integral part of the multidisciplinary team, ensuring the safe and effective use of all medications, educating patients and caregivers pre- and post-transplant, participating in multi-disciplinary selection meetings, and facilitating smooth transitions between patient care settings. Residents can expect dynamic experiences in caring for transplant recipients in the in-patient and outpatient settings while on core organ rotations as well as a focused ambulatory care experience. All required learning experiences are 1 month in duration except where noted in table below. Longitudinal experiences are designed to focus on pharmacy operations, clinical research and professional development which includes opportunities to deliver formal and informal presentations, teach and mentor residents and students, and develop professional writing skills. The transplant pharmacy group is very active in clinical research and collaborate on multiple research projects including PGY1 and PGY2 residents every year. Additionally, transplant pharmacists and residents will participate in ongoing prospective trials through enrollment and screening. The program will be tailored specifically for each resident based upon the resident’s goals, interests and previous experience.

Elective learning experiences are available to enhance the resident’s experience and knowledge in solid organ transplantation and related areas. Electives may be structured as two week, or one month learning experiences where noted below. Elective rotation requests will be considered on an individual basis, with regards to resident interests and preceptor availability.

Residency Goals

  • In collaboration with the health care team, provide comprehensive medication management to solid organ transplant patients following a consistent patient care process.
  • Ensure continuity of care during solid organ transplant patient transitions between care settings.
  • Manage and facilitate delivery of medications to support safe and effective drug therapy for solid organ transplant patients.
  • Demonstrate ability to manage formulary and medication-use processes for solid organ transplant patients, as applicable to the organization.
  • Demonstrate ability to conduct a quality improvement or research project.
  • Demonstrate leadership skills for successful self-development in the provision of care for solid organ transplant patients.
  • Demonstrate management skills in the provision of care for solid organ transplant patients.
  • Provide effective medication and practice-related education to solid organ transplant patients, caregivers, health care professionals, students, and the public (individuals and groups).
  • Effectively employ appropriate preceptor roles when engaged in teaching students, pharmacy technicians, or fellow health care professionals in solid organ transplant.

Learning Experiences

Required Rotations Elective Rotations Longitudinal Rotations
Orientation* Liver Transplantation II† Professional Development
  • Therapeutics Conference
  • Transplant Clinical Conference
  • Transplant Leadership Conference
  • Grand Rounds
  • Multidisciplinary Presentations
  • Preceptorship
  • Unit Based Clinical Leadership
  • Clinical Immunology Lab
Kidney/Pancreas Transplantation I Heart Transplantation II†
Kidney/Pancreas Transplantation II Critical Care (SICU or CTICU)†
Liver Transplantation I Bone Marrow Transplant†
Heart Transplantation I Transplant Ambulatory Care II‡
Lung Transplantation I Mechanical Circulatory Support‡
Lung Transplantation II Transplant Hepatology‡
Transplant Ambulatory Care l Transplant Nephrology‡
Transplant Infectious Disease ID Ambulatory Care‡
Pediatric Transplantation†§
Longitudinal Research
Pharmacy Operations

* 1-month experience; activities may vary based on in-coming early commitment status
† 1-month experience
‡ Available as 2-week, or 1-month experience
§ Children’s Hospital of Philadelphia; associated with additional screening and credentialing

Longitudinal Experiences

Professional Development

  • Provide an ACPE-accredited presentation at Pharmacy Grand Rounds
  • Present monthly topics to the transplant preceptors during monthly Transplant Clinical Conference
  • Present and mentor journal clubs and/or patient case presentations as part of the residency program’s Therapeutics Conference
  • Participate in Transplant Leadership Conference, an educational series focused on transplant administration and leadership
  • Develop and present lectures at the Transplant Coordinator Education Series, Transplant Nurses Day and the Kidney Transplant Symposium
  • Opportunities to attend multi-disciplinary education series to further supplement and enhance transplant knowledge including: Hepatology Conference, Renal Conference, Multi-disciplinary Immunology & Transplantation Interest Conference (MITI), Transplant Coordinator Education Series and didactic lectures on HLA and Immunology as part of the pathology residents training
  • Prepare or revise a transplant related protocol/treatment guideline, drug class review or monograph
  • Participate in the clinical intervention program, adverse drug reaction reporting program and medication error program
  • Serve as a secretary for the RP4 Unit Based Clinical Leadership and the monthly transplant clinical specialist meeting
  • Assist in mentoring and precepting to pharmacy students, PGY1 residents, and pharmacy staff
  • Additional opportunities for professional development may be offered based on interest and availability
    • American College of Clinical Pharmacy (ACCP) IMTR PRN blog
    • American Society of Transplantation (AST) Transplant Pharmacy Community of Practice Online Journal Club
    • International Society of Heart and Lung Transplantation (ISHLT)
      PULSE Newsletter
    • AST Fellow Conference Case Presentation
    • Journal article peer review
    • Serve as primary preceptor for an APPE student rotation or PGY1 resident
    • Participate in department, hospital and clinical unit committees as assigned

Research/Scholarly Activities

  • Involvement in research educational series focusing on epidemiology, study design, and statistical methods
  • Identify or choose a transplant specific research question and complete a research project including study design, statistical analysis, data collection and results analysis
  • Submit a transplant-related abstract to a national meeting
  • Develop a transplant-related poster and/or platform presentation for a national meeting
  • Attend a pharmacy and/or transplant related national meeting(s) as funding allows
  • Prepare a manuscript suitable for publication in a professional journal
  • Participate in kidney transplant research on call based on interest and availability
  • Mentor PGY1 residents who are participating in transplant related research
Residency Year Resident Research Projects Submitted to National Meetings
2017-2018 Stephanie Hamel Outcomes in Renal Transplant Recipients with Bipolar Disorder: A Large Retrospective Cohort
Evaluation of breakthrough cytomegalovirus infection in donor-positive/recipient-negative kidney transplant recipients
Use of Granulocyte-Colony Stimulating Factor for Leukopenia Post-Renal Transplantation
Cognitive Function and Health Literacy Assessment Outcomes in the First Months after Transplant in a Diverse Single Center Population
2018-2019 Nicole Persun Targeted antifungal prophylaxis in liver transplant recipients: two year, retrospective cohort analysis
Two-year, single center review of herbal supplement use in living kidney donation
Renal function outcomes at 6 and 12 months in liver transplant recipients utilizing a calcineurin inhibitor minimization strategy: a retrospective, single-center review
2019-2020 Maxwell Norris Evaluation of Oral Candidiasis Incidence at Large Academic Medical Center in Absence of Pharmacologic Prophylaxis at Discharge
Medication adherence assessment findings in kidney transplant candidates undergoing living donor transplant
Comparison of Stanford Integrated Psychosocial Assessment for Transplantation Scores to Medication Adherence Assessment Findings in Kidney Transplant Candidates Undergoing Living Donor Transplant
Does Historical Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers Therapy Slow Allograft Function Recovery Following Successful Kidney Transplantation/td>
Patient attitudes regarding contraception and pregnancy after transplantation
Health system encounters in kidney transplant recipients converted from immediate-release tacrolimus capsules to extended-release tacrolimus tablets
Characterization of Use and Safety of Non-Insulin Agents for Management of Post-Transplant Diabetes Mellitus in the Kidney Transplant Population

Pharmacy Operations

  • Function as a unit based clinical pharmacist during weekend staffing coverage in a transplant practice area, responsibilities include:
    • Order verification
    • Medication distribution
    • Pharmacokinetic consult recommendations
    • Drug information resource for health care providers
    • Emergency response participation at all codes, anesthesia stats, and rapid response calls for assigned units
      • Complete at least 208 hours of weekend clinical operations as a unit based clinical pharmacist
      • Basic Life Support and Advanced Cardiac Life Support certification to be completed during orientation if not already certified

Resources

The residency program provides residents sufficient resources to fulfill the responsibilities of the program, including:

  • A dedicated workspace
  • Technological resources, including, but not limited to, a workstation, clinical information systems, laptop computer, and cell phone
  • Access to online and print pharmacy and medical references
  • Extramural educational opportunities, such as conference attendance
  • Sufficient financial support, including salary ($52,000 annual stipend) and full benefits package (including 10 paid days off), reimbursement for conference attendance, statistical support for projects, and poster production
  • Professional liability insurance is covered by the hospital as long as residents are working within the limits of their job description and following hospital policies and procedures
  • Administrative time during each learning experience to complete residency related requirements
  • Transportation Reimbursement (Septa Pass or parking spot)

Program Information

  • Number of Positions: 1
  • NMS Code: 785876
  • Accreditation Status: Accredited

Training Site

  • The Hospital of the University of Pennsylvania is the largest institution within the University of Pennsylvania Health System (Penn Medicine) and is world-renowned for its clinical and research excellence, forging the way for new and better ways to diagnose and treat illnesses and disorders. HUP is a 793-bed academic teaching hospital and tertiary referral center located in the heart of Philadelphia.
  • The Penn Transplant Institute (PTI) performed their first successful kidney transplant in 1966, and since then has been a pioneer in organ transplantation, providing exceptional global care for the transplant recipient, and leading in cutting edge research in transplant science. Penn's multidisciplinary team leads the region in the total number of transplants performed and is ranked among the top 10 multi-organ transplant centers in the country. Penn has active programs in kidney, pancreas, liver, lung, heart, hand, uterus, and islet cell transplantation, as well as living donor programs for kidney and liver. In addition, the liver and kidney transplant programs at Penn Medicine and the Children's Hospital of Philadelphia (CHOP) have collaborated for decades to allow healthy adults to donate organ tissue to children with end-stage kidney or liver disease. Penn offers total integration of care for all transplant recipients from pre-surgery management, through the transplant surgery and postoperative care.
  • Penn’s reputation as a world leader in medical research and clinical care attracts the highest quality medical specialists from around the world. The supportive and collaborative environment encourages physicians and staff to keep reaching ahead to find new ways to improve the quality and length of life for everyone.
The Hospital of the University of Pennsylvania Transplant Volumes
To Date 2019 2018 2017
Total Volume
Kidney 4,953 241 199 191
Liver 3,083 135 133 125
Pancreas 40 2 0 0
Kidney/Pancreas 272 16 4 4
Heart 1,414 57 36 65
Lung 1,362 80 112 83
Heart/Lung 23 2 3 2
Uterus 3 1 1 0
Upper Limb 3 1 0 0
Transplants From Living Donors
Kidney 1,622 94 75 77
Liver 152 13 10 10
Uterus 1 0 0 0

Application Requirements

Candidates interested in the program should submit the following through PhORCAS:

  • Academic transcripts from your School of Pharmacy (including pre-pharmacy college transcripts)
  • Letter of intent
  • Curriculum vitae
  • Three letters of recommendation
    • PGY1 Residency Program Director
    • Clinical rotation preceptor, preferably from a transplant rotation
    • Other clinical preceptor

All required application materials should be submitted via PhORCAS by the 1/4/2021

Chelsea Sammons, PharmD, BCPS

Clinical Pharmacy Specialist, Liver Transplantation
Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104
Chelsea.Sammons@uphs.upenn.edu

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