Cardiovascular Research at Penn

This core facility assists PIs in developing and implementing in vivo rodent models of cardiovascular disease.


Photo of lab members at the physiology and microsurgery core facilityDr. Tao Wang, Core Director
Mouse Cardiovascular Physiology Core
Penn Cardiovascular Institute
University of Pennsylvania
Smilow Center for Translational Research Room 11-122 
3400 Civic Center Boulevard, Building 421 
Philadelphia, PA 19104

Dr. Ning Zhou 

Core Description

The Mouse Cardiovascular Physiology Core Facility, established in April 2006, is under the leadership of Dr. Tao Wang. Our goal is to aid investigators with the creation of mouse models related to cardiovascular diseases. We provide comprehensive assessments of cardiovascular structure and function using high-resolution echocardiographic imaging tools, which provides a unique and valuable research opportunity for translational research from animal studies to human applications. We deliver on-demand services that reveal important cardiovascular, structural, and functional aspects of mouse models in an efficient and cost-effective manner.

We offer a variety of surgical procedures, mouse models of cardiovascular disease, invasive hemodynamical measurements of pressure and ventricle function, high-resolution ultrasound imaging, and ECG/BP telemetry services for the comprehensive evaluation of cardiovascular phenotypes of transgenic and knockout mice. We perform surgical procedures that may be difficult or time-consuming for investigators without the proper expertise, experience, and/or equipment. Furthermore, we provide surgical training for various mouse models and data analysis for physiological assessment of cardiovascular function.

To find out more about our Mouse Cardiovascular Physiology Core Facility, please contact us or visit us at our core lab at the Smilow Center for Translational Research (11th Floor, Room 222).

Learn more about the Mouse Cardiovascular Physiology Core

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