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Department of Radiology: Research Grants

The Department of Radiology at Penn Medicine has an extensive portfolio of funding to support its research. Reflecting our broad, team-oriented approach to research, most funded efforts are multidisciplinary, and many involve other departments at Penn Medicine as well as collaborators inside and outside the University of Pennsylvania campus.

2019 GRANTS


NIH Grants Awarded to Penn Radiology

FY19 NIH Grants to the Department of Radiology at Penn Medicine

PI Sponsor Fund Desc Title
Spyridon Bakas, PhD National Cancer Institute/NIH/DHHS 1-U01-CA-242871-01 The Federated Tumor Segmentation (FeTS) platform: An intuitive tool facilitating secure multi-institutional collaboration
R. Nick Bryan, MD, PhD, FACR National Institute on Aging/NIH/DHHS 1-R01-AG-062819-01A1 CARDIA Year 35 Brain MRI Renewal
David P. Cormode, PhD National Cancer Institute/NIH/DHHS 5-R01-HL-131557-04 Biodegradable polymetal nanoparticle CT contrast agents for vascular imaging
David P. Cormode, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 5-R01-CA-227142-02 Nanoparticle contrast agents for earlier breast cancer detection
Christos Davatzikos, PhD National Cancer Institute/NIH/DHHS 5-R01-MH-112070-03 Mapping Heterogeneity of Neuroanatomical Imaging Signatures of Psychosis via Pattern Analysis
Christos Davatzikos, PhD National Cancer Institute/NIH/DHHS 5-U24-CA-189523-01A1 Cancer imaging phenomics software suite: application to brain and breast cancer
Christos Davatzikos, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 5-R01-EB-022573-03 Pattern Analysis of fMRI via machine learning/sparse models: application to brain development
Christos Davatzikos, PhD National Institute of Mental Health/NIH/DHHS 5-R01-MH-112070-02 Mapping Heterogeneity of Neuroanatomical Imaging Signatures of Psychosis via Pattern Analysis
Sudipto Dolui, PhD National Institute on Aging/NIH/DHHS 1-R03-AG-063213-01 Cerebral Blood Flow trajectory in the Alzheimer’s Disease continuum
Robert K. Doot, PhD National Institute on Drug Abuse/NIH/DHHS 5-K01-DA--040023-04 Methodology for PET Imaging of Role of Dopamine D3 Receptor in Addiction
Jacob G. Dubroff, MD, PhD National Institute on Drug Abuse/NIH/DHHS 5-K23-DA-038726-04 The influence of nicotinic hepatic metabolism on neuroreceptor substrates of nicotine addiction
Yong Fan, PhD National Cancer Institute/NIH/DHHS 5-R21-CA-223358-02 Learning radiomic signatures to early predict response of rectal cancer patients to neoadjuvant chemoradiation therapy
Yong Fan, PhD National Institute of Diabetes and Digestive and Kidney Diseases /NIH/DHHS 1-R21-DK-117297-01A1 Anatomic biomarkers of chronic kidney disease progression among children
Terence Gade, MD, PhD Office of the Director, National Institutes of Health/NIH/DHHS 5-DP5-OD-021391-04 Image-Based Phenotyping of Hepatocellular Carcinoma Cell Survival Under Ischemic Stress: Toward Metabolic Imaging of Cancer Dormancy Using Hyperpolarized Carbon-13 Technology
Terence Gade, MD, PhD National Cancer Institute/NIH/DHHS 1-R01-CA-234005-01A1 Targeting Ischemia-Induced Dependencies on the Metabolic Stress Response in Hepatocellular Carcinoma Through Image-Guided, Locoregional Therapy
Terence Gade, MD, PhD National Cancer Institute/NIH/DHHS 1-R44-CA-165312-UP  Development of a urine test for the early detection of liver cancer
James C. Gee, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 5-T32-EB-009384-11 Training Program in Biomedical Imaging and Informational Sciences
James C. Gee, PhD National Institute of Neurological Disorders and Stroke/NIH/DHHS 5-R01-NS-096720-04 Waxholm Space for Rodent Neuroinformatics
James C. Gee, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 5-R01-HL-133889-03 ITK-Lung: A Software Framework for Lung Image Processing and Analysis
James C. Gee, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 1-R13-EB-028135-01 International Conference on Information Processing in Medical Imaging 2019
Andrea Estefania Guzman, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 1-F31-EB-029309-01 Development of pH-Sensitive Probes for in vivo Cerenkov Imaging
Joel S. Karp, PhD National Cancer Institute/NIH/DHHS 5-R01-CA-113941-14 Time-of-Flight PET for Improved Whole-Body Imaging
Joel S. Karp, PhD National Cancer Institute/NIH/DHHS 1-R01-CA-225874-01A1 PennPET Explorer Scanner With Scalable Axial Length for Total Body PET Imaging
Despina Kontos, PhD National Cancer Institute/NIH/DHHS 5-R01-CA-197000-04 Multi-parametric 4-D Imaging Biomarkers for Neoadjuvant Treatment Response
Despina Kontos, PhD National Cancer Institute/NIH/DHHS 5-R01-CA-161749-07 Digital breast tomosynthesis imaging biomarkers for breast cancer risk estimation
Despina Kontos, PhD National Cancer Institute/NIH/DHHS 1-R01-CA-223816-02 Radiogenomic Biomarkers of Breast Cancer Recurrence
Lin Z. Li, PhD National Cancer Institute/NIH/DHHS 5-R01-CA-191207-05 Redox imaging for breast cancer prognosis
Robert H. Mach, PhD National Institute on Drug Abuse/NIH/DHHS 5-R01-DA-029840-09 PET Radiotracers for Imaging the Dopamine D3 Receptor
Robert H. Mach, PhD National Institute on Aging/NIH/DHHS 1-R21-AG-055142-02 Imaging oxidative stress in an animal model of AD with PET
Robert H. Mach, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 1-R01-EB-026988-02 Imaging the D2/A2A Heterodimer with PET
Robert H. Mach, PhD National Institute on Drug Abuse/NIH/DHHS 1-P30-DA-046345-01A1  Penn PET Addiction Center of Excellence (Penn PACE)
Robert H. Mach, PhD National Institute of Neurological Disorders and Stroke/NIH/DHHS
 1-U19-NS-110456-01A1 Center without Walls for Imaging Proteinopathies with PET (CW2IP2)
Robert H. Mach, PhD National Institute on Aging/NIH/DHHS 1-R42-AG-052249-02A1 Optimization of sigma-2 receptor modulators for the treatment of cognitive dysfunction
David A. Mankoff, MD, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 5-T32-EB-004311-15 Research Track Radiology Residency
David A. Mankoff, MD, PhD National Cancer Institute/NIH/DHHS 5-R01-CA-211337-03 Molecular Imaging Markers for Glutaminolysis in Breast Cancer
Samuel Matej, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 5-R01-EB-023274-03 Development and application of 4D TOF reconstruction for quantitative PET imaging
Scott D. Metzler, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 5-R01-HL-108119-08 Development of a High Performance Clinical Cardiac SPECT/TCT System
Anatoliy V. Popov, PhD National Cancer Institute/NIH/DHHS 5-R01-CA-201328-04 Phospholipase-activated theranostics for PDT of breast cancer
Alison M. Pouch, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 1-K01-HL-141643-02 A Platform for Outcomes Data Sharing and Pre-Operative Image-Guided Mechanistic Assessment for Bicuspid Aortic Valve Repair Surgery
Daniel Pryma, MD National Cancer Institute/NIH/DHHS 1-R01-CA-219006-02 PARP-1 as a novel target for alpha-particle therapy in high-risk Neuroblastoma
Chamith S. Rajapakse, PhD National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 1-R01-AR-076392-01
 MRI Assessment of Hip Fracture Risk and Therapy Response in HIV/HCV Coinfection
Chamith S. Rajapakse, PhD National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 5-R01-AR-068382-04 Clinical Assessment of Hip Fracture Biomechanics using MRI
Ravinder Reddy, PhD National Institute of Neurological Disorders and Stroke/NIH/DHHS 5-R01-NS-087516-05 A Novel Method for Glutamate Imaging ? IS THIS STILL ACTIVE? WASN'T ON LIST
Ravinder Reddy, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 5-P41-EB-015893-35 A Resource for Magnetic Resonance and Optical Imaging
Ravinder Reddy, PhD National Institute on Aging/NIH/DHHS 1-R56-AG-062665-01
 CrCEST MRI of Skeletal Muscle Metabolism
Rahim R. Rizi, PhD National Cancer Institute/NIH/DHHS 5-R01-CA-193050-05 A new imaging approach to radiotherapy planning for lung cancer
Rahim R. Rizi, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 5-R01-HL-129805-04 Prediction and assessment of COPD lung volume reduction outcomes with polarized MRI
Rahim R. Rizi, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 5-R01-HL-139066-03 Assessment of Lung Injury with integrated Imaging Techniques
Rahim R. Rizi, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 1-R01-HL-142258-02 Improving lung transplant outcomes through the use of imaging in a DBD rat model
Mark Rosen, MD, PhD National Cancer Institute/NIH/DHHS U24-CA-180803
 American College of Radiology
Chandra M. Sehgal, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 5-R01-EB-022612-04 Tunable microbubbles for antivascular ultrasound
Chandra M. Sehgal, PhD National Cancer Institute/NIH/DHHS
 5-R01-CA-204446-03 Antivascular ultrasound therapy of primary liver neoplasia
Mark A. Sellmyer, PhD Office of the Director, National Institutes of Health/NIH/DHHS DP5OD026386-02 Next generation tools for imaging bacterial infection and its relationship to the immune system
Suleman Surti, PhD National Cancer Institute/NIH/DHHS 5-R01-CA-196528-03 High Performance, Quantitative Breast PET Scanner Integrated with Tomosynthesis
Suleman Surti, PhD National Cancer Institute/NIH/DHHS  1-R21-CA-239177-01A1 Energy-Based Scatter Estimation Algorithm for Accurate Quantitative PET Imaging
Matthew Dylan Tisdall, PhD National Institute on Drug Abuse/NIH/DHHS 3-R34-DA-050297-01 A feasibility study of novel technologies to minimize motion-induced biases in functional and structural MRI of young, opioid-affected cohorts
Ragini Verma, PhD National Institute of Neurological Disorders and Stroke/NIH/DHHS 5-R01-NS-096606-04 Connectomics meets neuro-oncology: mapping the brain for treatment planning
Ragini Verma, PhD National Institute of Child Health and Human Development/NIH/DHHS 5-R01-HD-089390-03 Temporal connectomics for infant brain: neurodevelopment modulated by pathology
Ragini Verma, PhD National Institute of Mental Health/NIH/DHHS 1-R01-MH-117807-01A1
 Harmonization for multisite Connectomics: parsing heterogeneity and creating markers in ASD
Felix W. Wehrli, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 1-T32-EB-020087-04 Training in Structural, Physiologic and Functional MRI
Felix W. Wehrli, PhD National Institute of Dental and Craniofacial Research/NIH/DHHS 1-R21-DE-028417-01 Solid-State MRI as a Noninvasive Alternative to Computed Tomography for Craniofacial Imaging
Felix W. Wehrli, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 5-R01-HL-139358-03 MRI and Serum Markers of Endothelial Stress Resulting from E-Cigarette Aerosol Inhalation
Walter R. Witschey, PhD
 National Heart, Lung, and Blood Institute/NIH/DHHS 1-R01-HL-137984-02 Cardiac MR imaging of hemorrhagic reperfusion injury after myocardial infarction
Paul A. Yushkevich, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 5-R01-EB-017255-05 Adaptive Large-Scale Framework for Automatic Biomedical Image Segmentation (IS THIS ACTIVE?)
Paul A. Yushkevich, PhD National Institute on Aging/NIH/DHHS 5-R01-AG-056014-03 AD-specific changes in the MTL: Novel biomarkers using in vivo / ex vivo imaging
Rong Zhou, PhD National Cancer Institute/NIH/DHHS 1-U24-CA-231858-02 Penn Quantitative MRI Resource for Pancreatic Cancer

Additional Grants With a Penn Radiology mPI

FY19 Additional Outside Grant Awards with Penn Radiology mPIs

PI Sponsor Fund Desc Title
Jim Delikatny, PhD (mPI) NCI 5R01CA226412-02 Near-infrared Choline Kinase Sensors for Intraoperative Identification of Lung Tumor Margins
Michael Farwell, MD (mPI) NIBIB 1R01EB-026892 Quantitative control of CAR T cells via image-guided delivery and monitoring
James C. Gee, PhD (mPI) NIMH 5R01-HL130468-05 A computational biomechanical airway model for obese children at risk for OSAS
Despina Kontos, PhD (mPI) NINDS 5R01CA207084-03 Radiomic Phenotypes of Breast Parenchyma and Association With Breast Cancer Risk and Detection
Scott Metzler, PhD (mPI) NHLBI 1R01HL-145786-01A1 SPECT imaging of Peripheral Vascular Disease
Jayaram K. Udupa, PhD (mPI) NHLBI 1-R42-CA-199735 Automated object contouring methods & software fo radiotherapy planning
Jayaram K. Udupa, PhD (mPI) NIMH 5U24MH114827-03 A community resource for single cell data

NIH Grants Awarded to the CHOP Radiology Department

FY19 NIH Awards to the Department of Radiology at CHOP

PI Sponsor Fund Desc Title
Sudha Anupindi, MD (CHOP PI) NIDDKD 5R01-DK118964-02 Noninvasive portal pressure measurements in children
Luke Bloy, PhD NIMH K01MH108762-04 MEG Imaging Techniques for Low-functioning Pediatric Populations
Yu-Han Chen, PhD NIMH K01MH108822-05 Development of Infant Brain MEG Responses to Social Stimuli: Comparison to ASD
James Christopher Edgar, PhD NICHD R01HD093776-02 Brain Structure and Function in Infants
James Christopher Edgar, PhD NIMH R01MH107506-04 A Longitudinal Study of Brain Development in Children With Autism
Hao Huang, PhD NIMH R01MH092535-09 Structural Development of Human Fetal Brain
Misun Hwang, PhD (CHOP PI) NCATS 5KL2-TR001879-04 Institutional Clinical and Translational Science Award
Arastoo Vossough Modarress, PhD (CHOP PI) NIBIB 5R01-EB020683-04 Quantitative image modeling for brain tumor analysis and tracking
Timothy P. Roberts, PhD NIDCD R01DC008871-10 Electrophysiological Signatures of Language Impairment in Autism Spectrum Disorder
Joni Saby, PhD (CHOP PI) NIMH 1K01-MH118378-01A1 Neural signatures of tactile processing and sensorimotor GABA in development and Autism Spectrum Disorder

Subcontracts

Penn Radiology Subcontracts FY19

PI Sponsor Fund Desc Title
R. Nick Bryan, MD, PhD, FACR Wake Forest University 101720-112971 The Macrovascular and Microvascular Contributions to Alzheimer's Disease
R. Nick Bryan, MD, PhD, FACR Wake Forest University WFUHS-551083
 MESA Multisite Alzheimer's (AD) study
Emily F. Conant, MD University of Vermont 32088SUB52367 Multicenter evaluation of digital breast tomosynthesis with synthesized two-dimensional mammography for breast cancer screening
Tessa S. Cook, MD, PhD American College Of Radiology ACR Integrated National Imaging Informatics Course (I3) – Educating the Next Generation of Radiologists and Fostering Interest in Data Science and Imaging Informatics
Tessa S. Cook, MD, PhD Thomas Jefferson University 080-30000-U20201  MissMap: A point-of-care tool to show study specific infographics displaying the location and types of commonly missed findings based on 10 years of discrepancy data and associated example cases and educational content
Christos Davatzikos, PhD Old Dominion University Research Foundation 16-249-100594-010 Quantitative Image Modeling for Brain Tumor Analysis and Tracking
Christos Davatzikos, PhD Johns Hopkins University 2003994874 Preclinical AD Consortium
Christos Davatzikos, PhD National Institute On Drug Abuse/NIH/DHHS 75N95019C00022 Quantitative Analysis of Longitudinal MR Images in BLSA Participants
Christos Davatzikos, PhD New York University School Of Medicine SUB TO DP3DK114812 Effects of Biomedical Risk Factors on Neuro-cognition Using MRI: Long term follow-up of the Diabetes Control & Complications Trial/Epidemiology of Diabetes Interventions and Complications Study Cohort
Christos Davatzikos, PhD University Of Maryland, Baltimore 1200011D REQUEST:2765 Claude D. Pepper Older Americans Independence Center
Christos Davatzikos, PhD VA 36C24519C0130 MRI Image Analysis for the Geriatric Research Education Clinical Center (GRECC) in the VA Maryland Health Care System
Joel S. Karp, PhD University of California, Davis 201501155-01/A16-0114-S002 EXPLORER: Changing the Molecular Imaging Paradigm with Total Body PET
Despina Kontos, PhD Mayo Clinic Rochester UOP-225625-04 Radiomic phenotypes of breast parenchyma and breast cancer risk and detection
Despina Kontos, PhD University Of North Carolina At Chapel Hill
 5114713 Understanding the biological basis for the association between parenchymal texture features and breast cancer risk
Dushyant Kumar, PhD Children's Hospital Of Philadelphia 4263210520 Glutamate Toxicity as a Component of Progressive Thalamic Damage in Multiple Sclerosis
Scott D. Metzler, PhD University Of Illinois  097337-17723 SPECT Imaging of Peripheral Vascular Disease
Bryan A. Pukenas, MD Children's Hospital Of Philadelphia  4263210520 Improving Pediatric Cardiac Arrest Survival and Neurologic Outcome
Chamith S. Rajapakse, PhD New York University 16-A0-00-005518-01 Translation of Hip Microarchitectural Assessment Technology to the Clinic to Diagnose Glucocorticoid-Induced Osteoporosis
Chamith S. Rajapakse, PhD New York University 18-A1-00-1000572 MRI of proximal femur bone quality for monitoring short-term response to osteoporosis therapy
Chamith S. Rajapakse, PhD Children's Hospital Of Philadelphia 4263450820 Defining Bone Sarcoma Tumor Margin Using Novel MRI Biomarkers
Chamith S. Rajapakse, PhD University Of Florida PTCEMF-GD-004 PTCEMF-GD-004: A Multicenter Randomized, Placebo-Controlled Phase III Study on the Safety and Efficacy of Deflazacort (Emflaza®) in Patients with Limb-Girdle Muscular Dystrophy 2I (LGMD2I)
Ravinder Reddy, PhD University of Miami SPC-000724 Development and Maintenance of Software for MR Spectroscopic Imaging
Mark Rosen, MD, PhD American College of Radiology 1672 ECOG-ACRIN-Based QIN Resource for Advancing Quantitative Cancer Imaging in Clinical Trials
Mark Rosen, MD, PhD American College of Radiology 1824 Imaging & Radiation Oncology Core - Philadelphia Imaging Core Lab Director
Mitchell D. Schnall, MD, PhD, FACR ECOG-ACRIN Medical Research Foundation, Inc. U24CA196172-01-UPA1 ECOG-ACRIN Biorepositories to Support NCTN
Chandra M. Sehgal, PhD Osciflex, LLC SEH2019-1
 Mechanical Generation of Peri-Valvular Oscillatory Flow to Prevent Deep Venous Thrombosis
Michael C. Soulen, MD Thomas Jefferson University 080-30000-S22601 2D and 4D Contrast-enhanced Ultrasound Evaluation of Hepatocellular Carcinoma Chemoembolization
Jayaram K. Udupa, PhD Albert Einstein College of Medicine, Inc. 311072 A Computational Biomechanical Airway Model for Obese Children at Risk for OSAS
Jayaram K. Udupa, PhD Children's Hospital of Philadelphia RFRNT17002 Center for Thoracic Insufficiency Syndrome (CTIS) Frontier Program
Paul A. Yushkevich, PhD Northern California Institute for Research and Education WEI-2015-17 Medial Temporal Lobe Subregion MRI Biomarkers for ADNI3

Subprojects

Penn Radiology Subprojects FY19

PI Sponsor Fund Desc Title
David P. Cormode, PhD National Institute Of Dental And Craniofacial Research/NIH/DHHS 5-R01-DE-025848-04 Biofilm Elimination and Caries Prevention using Multifunctional Nanocatalysts
Jim Delikatny, PhD National Cancer Institute/NIH/DHHS 5-P30-CA-016520-42 Abramson Cancer Center Support Grant
Yong Fan, PhD National Institute Of Mental Health/NIH/DHHS 1-R01-MH-120811-01 Individualized Closed Loop TMS for Working Memory Enhancement
Michael Farwell, MD Carisma Therapeutics, Inc. CARISMA THERAPEUTICS (1) CAR-Macrophage Mechanism of Action and CT-0508 IND Enabling Work, Process Development, Manufacturing Enhancements, and Macrophage Durability Improvements; (2) Toward autologous self-manufacturing of CAR macrophages for the treatment of cancer and for neurodegenerative diseases
David A. Mankoff, MD, PhD National Cancer Institute/NIH/DHHS 5-P30-CA-016520-42 Abramson Cancer Center Support Grant
Austin Ryan Pantel, MD National Cancer Institute/NIH/DHHS 5-P30-CA-016520-42 Abramson Cancer Center Support Grant
Anatoliy V. Popov, PhD National Institute Of Neurological Disorders And Stroke/NIH/DHHS 5-R01-NS-100892-03 Targeted Treatment for Radiculopathy Via Engineered PLA2-responsive Multifunctional Micelles
Chamith S. Rajapakse, PhD National Institute Of Allergy And Infectious Diseases/NIH/DHHS 2-P30-AI-045008-21 Penn Center for AIDS Research
Mitchell D. Schnall, MD, PhD, FACR National Center For Advancing Translational Sciences/NIH/DHHS 5-UL1-TR-001878-04 Institutional Clinical and Translational Science Award
Joel M. Stein, MD, PHD National Institute Of Neurological Disorders And Stroke/NIH/DHHS 5-R01-NS-100892-03 Targeted Treatment for Radiculopathy via Engineered PLA2-responsive Multifunctional Micelles
Paul A. Yushkevich, PhD National Institute On Aging/NIH/DHHS 5-P30-AG-010124-29 Alzheimer's Disease Core Center

Foundations

Penn Radiology Foundation Grants FY19

PI Sponsor Fund Desc Title
Jamaal L. Benjamin, MD RSNA Research & Education Foundation
 RR1907 Leveraging Epigenetic Alterations to the Tumor Microenvironment to Potentiate the Endogenous Immune Response in HCC
Paco Bravo, MD, PhD RSNA Research & Education Foundation RSD1903 Somatostatin Receptor-Targeted Imaging for Monitoring Disease Activity in Cardiac Sarcoidosis
Joshua Choi, MD RSNA Research & Education Foundation RR1916 The Effects of Increased Intracranial Pressure on Brain Perfusion Using Contrast-Enhance Ultrasound in a Pediatric-Aged Porcine Model of Post-Hemorrhagic Hydrocephalus
Tessa S. Cook, MD, PhD RSNA Research & Education Foundation EDPE1904 Improving Patients’ Understanding Of Common Actionable Imaging Findings In The Abdomen And Pelvis
Tessa S. Cook, MD, PhD Society of Imaging Informatics in Medicine N/A National Imaging Informatics Curriculum & Course
Michael D. Farwell, MD American Association for Cancer Research SU2C-AACR-IRG-15-17 Imaging CAR T Cells with a Dual Function PET Reporter Gene
Terence Gade, MD, PhD American Cancer Society RSG-18-203-01-TBG Targeting the Metabolic Stress Response in Hepatocellular Carcinoma
Robert H. Mach, PhD
 Fox (Michael J.) Foundation For Parkinson's Research  12267.01 Imaging iNOS in Parkinson's Disease with PET
Robert H. Mach, PhD  Fox (Michael J.) Foundation For Parkinson's Research  14638.01 Developing an Alpha-Synuclein Imaging Agent
David A. Mankoff, MD, PhD Susan G. Komen Breast Cancer Foundation SAC130060 Molecular Imaging of Breast Cancer Metabolism to Predict In Vivo Cancer Behavior
Ilya M. Nasrallah, MD, PhD American Society Of Neuroradiology 2019 Boerger Research Evaluation of [F18]NOS as a Novel PET Radiotracer for Neuroinflammation in Alzheimer’s Disease
Brian J. Park, MD RSNA Research & Education Foundation RF1913 Development of Intraoperative 3D Holographic Augmented Reality-Assisted Navigation System for CT­-Guided Percutaneous Ablations
Nicholas Perkons Society of Interventional Radiology  N/A Precision molecular imaging to assess response to loco-regional therapy: development of an unbiased platform for metabolic probe selection for evaluation of treatment response following trans-arterial embolization in hepatocellular carcinoma
Daniel Pryma, MD NRG Oncology NRG-Pryma-GY6 NRG Oncology Network Group Operations Center
Mark A. Sellmyer, PhD Burroughs Wellcome Fund 1018469 Engineering Digital Logic for Imaging Cell-Cell Interactions
Senthil Selvaraj, MD American Society Of Nuclear Cardiology  N/A Comparison of the Short-Term Effect of Dietary Carbohydrate Restriction Versus Exogenous Ketone Supplementation on Myocardial Glucose Suppression and Timing to Achieve a State of Ketosis Using Serial Imaging on a State-of-the Art Total-Body PET System
Chintan Shah, MD RSNA Research & Education Foundation RF1916 Impact of Intensive Systolic Blood Pressure Control on Brain Functional Network Integrity
Jae W. Song, MD RSNA Research & Education Foundation RSCH1929 Sex-Differences in Intracranial Arterial Wall Changes Using 3T and 7T Multicontrast Vessel Wall Imaging
Laura E. Wisse, PhD Alzheimer's Association AARF-19-615258 Etiology and Progression of Suspected Non-Alzheimer’s Pathophysiology
Chenbo Zeng, PhD National Comprehensive Cancer Network  N/A PET imaging of cell cycle arrest for predicting response to abemaciclib alone or in combination with endocrine therapy

MISC: DOD, Industry and State of Pennsylvania

Penn Radiology Miscellaneous Grants FY19

DOD

PI Sponsor Fund Desc Title
Raymond Acciavatti, Ph.D. Army W81XWH1810082 Design of a 3D Mammography System in the Age of Personalized Medicine

INDUSTRY

PI Sponsor Fund Desc Title
Paco Bravo, MD, PhD GE Healthcare GE-265-303 A Phase 3, Open-Label, Multicentre Study of Flurpiridaz (18F) Injection for Positron Emission Tomography (PET) Imaging for Assessment of Myocardial Perfusion in Patients Referred for Invasive Coronary Angiography Because of Suspected Coronary Artery Disease
Jacob G. Dubroff, MD, PhD Iqvia Rds Inc.  PD-1105 Imaging Contract for A Randomized, Placebo Surgery Controlled, Double-blinded, Multi-center, Phase 2 Clinical Trial, Evaluating the Efficacy and Safety of VY-AADC02 in Advanced Parkinson's Disease with Motor Fluctuations
Michael D. Farwell, MD ImaginAb, Inc. IAB-CD8-201 A Phase II, Open Label, Multi-Dose Study of 89ZR-DF-IAB22M2C (CD8 PET Tracer) For Positron Emission Tomography (PET/CT) in Patients With Metastatic Solid Tumors
Joel S. Karp, PhD Siemens Medical Solutions USA, Inc. N/A Methods and performance of long axial FoV scanners
Laurie A. Loevner, MD Guerbet, LLC  GDX-44-010 Efficacy and Safety of gadoPIClenol for CenTral NervoUs System (CNS) Magnetic REsonance Imaging (MRI) Phase III Clinical Trial: The PICTURE trial
Elizabeth S. McDonald, MD  Metavivor  N/A In vivo visualization and quantification of pharmacodynamics response to PARPi therapy
Seyed Ali Nabavizadeh, MD Blue Earth Diagnostics Limited IRB #832812 Multimodality [18F]Fluciclovine PET, MRI and cell free circulating DNA to differentiate tumor progression from pseudoprogression in patients with glioblastoma
Peter B. Noel, PhD Philips Medical Systems  Philips Healthcare
Research Plan for New Concepts in Spectral CT
Austin Ryan Pantel, MD Precision Oncology  PyL3301 A Phase 3, Multi-Center, Open-Label Study to Assess the Diagnostic
Performance and Clinical Impact of 18F-DCFPyL PET/CT Imaging
Results in Men with Suspected Recurrence of Prostate Cancer(CONDOR)
Joel M. Stein, MD, PHD Hyperfine Research, Inc. STEIN_HYPERFINE_CTA Evaluation of Hyperfine Low Field Portable Point-of-Care Magnetic Resonance Imaging System in Patients with Hydrocephalus

STATE OF PA FUNDING

PI Sponsor Fund Desc Title
David A. Mankoff, MD, PhD American College of Radiology SUB TO 4100068708 CURE 12 Improving Quantitative Imaging Biomarker Methods to Accelerate the Development of Effective Cancer Therapies

 

2018 GRANTS


FY18 NIH Grants to the Department of Radiology at Penn Medicine

PI Sponsor Fund Desc Title
David P. Cormode, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 5-R01-HL-131557-03 Biodegradable polymetal nanoparticle CT contrast agents for vascular imaging
David P. Cormode, PhD National Cancer Institute/NIH/DHHS 1-R01-CA-227142-01 Nanoparticle contrast agents for earlier breast cancer detection
Christos Davatzikos, PhD National Institute of Neurological Disorders and Stroke/NIH/DHHS 5-R01-NS-042645-15 Predicting brain tumor progression via multiparametric image analysis and modeling
Christos Davatzikos, PhD National Cancer Institute/NIH/DHHS 5-U24-CA-189523-01A1 Cancer imaging phenomics software suite: application to brain and breast cancer
Christos Davatzikos, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 5-R01-EB-022573-03 Pattern Analysis of fMRI via machine learning/sparse models: application to brain development
Christos Davatzikos, PhD National Institute of Mental Health/NIH/DHHS 5-R01-MH-112070-02 Mapping Heterogeneity of Neuroanatomical Imaging Signatures of Psychosis via Pattern Analysis
Robert K. Doot, PhD National Institute on Drug Abuse/NIH/DHHS 5-K01-DA--040023-03 Methodology for PET Imaging of Role of Dopamine D3 Receptor in Addiction
Jacob G. Dubroff, MD, PhD National Institute on Drug Abuse/NIH/DHHS 5-K23-DA-038726-03 The influence of nicotinic hepatic metabolism on neuroreceptor substrates of nicotine addiction
Yong Fan, PhD National Cancer Institute/NIH/DHHS 5-R21-CA-223358-02 Learning radiomic signatures to early predict response of rectal cancer patients to neoadjuvant chemoradiation therapy
Terence Gade, MD, PhD Office of the Director, National Institutes of Health/NIH/DHHS 5-DP5-OD-021391-04 Image-Based Phenotyping of Hepatocellular Carcinoma Cell Survival Under Ischemic Stress: Toward Metabolic Imaging of Cancer Dormancy Using Hyperpolarized Carbon-13 Technology
James C. Gee, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 5-T32-EB-009384-10 Training Program in Biomedical Imaging and Informational Sciences
James C. Gee, PhD National Institute of Neurological Disorders and Stroke/NIH/DHHS 5-R01-NS-096720-03 Waxholm Space for Rodent Neuroinformatics
James C. Gee, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 5-R01-HL-133889-02 ITK-Lung: A Software Framework for Lung Image Processing and Analysis
Joel S. Karp, PhD National Cancer Institute/NIH/DHHS 5-R01-CA-113941-13 Time-of-Flight PET for Improved Whole-Body Imaging
Despina Kontos, PhD National Cancer Institute/NIH/DHHS 5-R01-CA-197000-03 Multi-parametric 4-D Imaging Biomarkers for Neoadjuvant Treatment Response
Despina Kontos, PhD National Cancer Institute/NIH/DHHS 5-R01-CA-161749-06 Digital breast tomosynthesis imaging biomarkers for breast cancer risk estimation
Despina Kontos, PhD National Cancer Institute/NIH/DHHS 1-R01-CA-223816-01A1 Radiogenomic Biomarkers of Breast Cancer Recurrence
Despina Kontos, PhD National Cancer Institute/NIH/DHHS 1-R13-CA-225202-01A1 MICCAI 2018 - 21th International Conference on Medical Image Computing and Computer Assisted Intervention
Lin Z. Li, PhD National Cancer Institute/NIH/DHHS 5-R01-CA-191207-04 Redox imaging for breast cancer prognosis
Robert H. Mach, PhD National Institute on Drug Abuse/NIH/DHHS 5-R01-DA-029840-09 PET Radiotracers for Imaging the Dopamine D3 Receptor
Robert H. Mach, PhD National Institute on Aging/NIH/DHHS 1-R21-AG-055142-01A1 Imaging oxidative stress in an animal model of AD with PET
Robert H. Mach, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 1-R01-EB-026988-01 Imaging the D2/A2A Heterodimer with PET
David A. Mankoff, MD, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 5-T32-EB-004311-14 Research Track Radiology Residency
David A. Mankoff, MD, PhD National Cancer Institute/NIH/DHHS 5-R01-CA-211337-03 Molecular Imaging Markers for Glutaminolysis in Breast Cancer
Samuel Matej, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 5-R01-EB-023274-02 Development and application of 4D TOF reconstruction for quantitative PET imaging
Scott D. Metzler, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 5-R01-HL-108119-07 Development of a High Performance Clinical Cardiac SPECT/TCT System
Ipek Oguz, PhD National Institute of Neurological Disorders and Stroke/NIH/DHHS 5-R01-NS-094456-03 Early Detection of Huntington's Disease: Longitudinal Analysis of Basal Ganglia and Cortical Thickness
Anatoliy V. Popov, PhD
 National Cancer Institute/NIH/DHHS 5-R01-CA-201328-03 Phospholipase-activated theranostics for PDT of breast cancer
Alison M. Pouch, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 1-K01-HL-141643-01 A Platform for Outcomes Data Sharing and Pre-Operative Image-Guided Mechanistic Assessment for Bicuspid Aortic Valve Repair Surgery
Daniel Pryma, MD National Cancer Institute/NIH/DHHS 1-R01-CA-219006-01A1 PARP-1 as a novel target for alpha-particle therapy in high-risk Neuroblastoma
Chamith S. Rajapakse, PhD National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 5-R01-AR-068382-04 Clinical Assessment of Hip Fracture Biomechanics using MRI
Ravinder Reddy, PhD National Institute of Neurological Disorders and Stroke/NIH/DHHS 5-R01-NS-087516-05 A Novel Method for Glutamate Imaging
Ravinder Reddy, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 5-P41-EB-015893-34 A Resource for Magnetic Resonance and Optical Imaging
Rahim R. Rizi, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 5-R01-HL-124986-04 A New Approach for the Assessment of Pulmonary Inflammation
Rahim R. Rizi, PhD National Cancer Institute/NIH/DHHS 5-R01-CA-193050-04 A new imaging approach to radiotherapy planning for lung cancer
Rahim R. Rizi, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 5-R01-HL-127969-04 Imaging-based characterization of the COPDGene cohort
Rahim R. Rizi, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 5-R01-HL-129805-03 Prediction and assessment of COPD lung volume reduction outcomes with polarized MRI
Rahim R. Rizi, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 5-R01-HL-139066-02 Assessment of Lung Injury with integrated Imaging Techniques
Rahim R. Rizi, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 1-R13-EB-026337-01 Fifth International Workshop on Metabolic Imaging
Rahim R. Rizi, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 1-R13-HL-144010-01 2018 International Molecular and Functional Pulmonary Imaging Workshop
Rahim R. Rizi, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 1-R01-HL-142258-01A1 Improving lung transplant outcomes through the use of imaging in a DBD rat model
Chandra M. Sehgal, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 5-R01-EB-022612-03 Tunable microbubbles for antivascular ultrasound
Chandra M. Sehgal, PhD National Cancer Institute/NIH/DHHS
 5-R01-CA-204446-03 Antivascular ultrasound therapy of primary liver neoplasia
Mark A. Sellmyer, PhD Office of the Director, National Institutes of Health/NIH/DHHS DP5OD026386-01 Next generation tools for imaging bacterial infection and its relationship to the immune system
Suleman Surti, PhD National Cancer Institute/NIH/DHHS 5-R01-CA-196528-03 High Performance, Quantitative Breast PET Scanner Integrated with Tomosynthesis
Ragini Verma, PhD National Institute of Neurological Disorders and Stroke/NIH/DHHS 5-R01-NS-096606-02 Connectomics meets neuro-oncology: mapping the brain for treatment planning
Ragini Verma, PhD National Institute of Child Health and Human Development/NIH/DHHS 5-R01-HD-089390-03 Temporal connectomics for infant brain: neurodevelopment modulated by pathology
Felix W. Wehrli, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 5-R01-HL-122754-04 Neurometabolic Assessment of Obstructive Sleep Apnea by MRI
Felix W. Wehrli, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 1-T32-EB-020087-01A1 Training in Structural, Physiologic and Functional MRI
Felix W. Wehrli, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 5-R21-EB-022687-02 Dynamic MRI Mapping of CMRO2 Responses
Felix W. Wehrli, PhD National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 5-R01-AR-050068-10 Bone Water and Mineralization Measured by Nuclear Magnetic Resonance
Felix W. Wehrli, PhD National Heart, Lung, and Blood Institute/NIH/DHHS 5-R01-HL-139358-02 MRI and Serum Markers of Endothelial Stress Resulting from E-Cigarette Aerosol Inhalation
Walter R. Witschey, PhD
 National Heart, Lung, and Blood Institute/NIH/DHHS 1-R01-HL-137984-01A1 Cardiac MR imaging of hemorrhagic reperfusion injury after myocardial infarction
Paul A. Yushkevich, PhD National Institute of Biomedical Imaging and Bioengineering/NIH/DHHS 5-R01-EB-017255-05 Adaptive Large-Scale Framework for Automatic Biomedical Image Segmentation
Paul A. Yushkevich, PhD National Institute on Aging/NIH/DHHS 5-R01-AG-056014-02 AD-specific changes in the MTL: Novel biomarkers using in vivo / ex vivo imaging
Rong Zhou, PhD National Cancer Institute/NIH/DHHS 1-U24-CA-231858-01 Penn Quantitative MRI Resource for Pancreatic Cancer

Additional Grants With a Penn Radiology mPI

PI Sponsor Fund Desc Title
Sudha Ayyala Anupindi, MD (mPI) NIDDKD 1R01DK118964-01 Noninvasive Portal Pressure Measurements in Children
Jim Delikatny, PhD (mPI) NCI 5R01CA226412-01 Near-infrared Choline Kinase Sensors for Intraoperative Identification of Lung Tumor Margins
David S. Followill, MD (mPI) American College of Radiology U24CA180803-06 Imaging & Radiation Oncology Core – Philadelphia Imaging Core Lab Director
James C. Gee, PhD (mPI) NIMH 5U24MH114827-02 A Community Resource for Single Cell Data in the Brain
Despina Kontos, PhD (mPI) NINDS 5R01CA207084-02 Radiomic Phenotypes of Breast Parenchyma and Association With Breast Cancer Risk and Detection
Mitchell D. Schnall, MD, PhD, FACR NCI 5UG1CA189828-05 ECOG-ACRIN NCORP Research Base
Mitchell D. Schnall, MD, PhD, FACR NCI 5U01CA190254-04 ECOG-ACRIN-Based QIN Resource for Advancing Quantitative Cancer Imaging in Clinical Trials
Mitchell D. Schnall, MD, PhD, FACR NCI 5U10CA180820-05 ECOG-ACRIN Operations Center
Mitchell D. Schnall, MD, PhD, FACR NCI 5U10CA180820-05S1 ECOG-ACRIN Operations Center
Jayaram K. Udupa, PhD (mPI) NHLBI 6R01HL130468-04 A Computational Biomechanical Airway Model for Obese Children at Risk for OSAS
Jayaram K. Udupa, PhD (mPI) NIH(Office of Director) 3R01HL130468-03S1 A Computational Biomechanical Airway Model for Obese Children at Risk for OSAS

NIH Grants Awarded to the CHOP Radiology Department

PI Sponsor Fund Desc Title
Jeffrey I. Berman, PhD NIMH R21MH110869-02 Phase Amplitude Coupling and Dysfunction ACD
Luke Bloy, PhD NIMH K01MH108762-03 MEG Imaging Techniques for Low-functioning Pediatric Populations
Yuhan Chen, PhD NIMH K01Mh108822-04 Development of Infant Brain Meg Responses to Social Stimuli: Comparison to ASD
James Christopher Edgar, PhD NICHD R01HD093776-01 Brain Structure and Function in Infants
James Christopher Edgar, PhD NIMH R01MH107506-03 A Longitudinal Study of Brain Development in Children With Autism
Hao Huang, PhD NIMH R01MH092535-08 Structural Development of Human Fetal Brain
Timothy P. Roberts, PhD (MPI) NINDS R21NS106135-01 Neurophysiological and Neuroanatomical Processes Related to Autism Spectrum Disorder in Neurofibromatosis Type 1
Timothy P. Roberts, PhD NIDCD R01DC008871-10 Electrophysiological Signatures of Language Impairment in Autism Spectrum Disorder
Timothy P. Roberts, PhD NICHD U54HD086984-03 (8062) Neuroimaging and Neurocircuitry: Core E
Timothy P. Roberts, PhD NICHD U54HD086984-03 (8064) MEG Studies of Auditory Processing in Minimally/Non-verbal Children With ASD and Intellectual Disability

Subcontracts FY2018

PI Sponsor Fund Desc Title
Predrag R. Bakic, PhD University of California, Santa Barbara KK1614 Assessment of Medical Image Quality with Foveated Search Models
Ari Borthakur, PhD, MBA. Thomas Jefferson University 080-23000-S13301 Disruption of Osmoregulation Promotes Degenerative Disc Disease
R. Nick Bryan, MD, PhD, FACR Wake Forest University WFUHS 330159 Systolic Blood Pressure Intervention Trial (SPRINT)
R. Nick Bryan, MD, PhD, FACR University of Alabama at Birmingham 000504619-001 Processing Speed Training to Preserve Driving and Function Competencies in MCI
R. Nick Bryan, MD, PhD, FACR University of Washington UWSC8520 Atrial fibrillation burden, vascular disease of the brain and cardiac MRI in MESA
R. Nick Bryan, MD, PhD, FACR Wake Forest University 101720-112971 The Macrovascular and Microvascular Contributions to Alzheimer's Disease
Emily F. Conant, MD University of Vermont 32088SUB52367 Multicenter evaluation of digital breast tomosynthesis with synthesized two-dimensional mammography for breast cancer screening
Emily F. Conant, MD OM1 N/A Effectiveness and Value of Digital Breast Tomosynthesis: Outcomes Analysis of Breast Cancer Screening
David P. Cormode, PhD Polyaurum LLC SUB TO 1R41EB023169 Biodegradable gold nanoparticles as contrast agents for CT
Christos Davatzikos, PhD Old Dominion University Research Foundation 16-249-100594-010 Quantitative Image Modeling for Brain Tumor Analysis and Tracking
Christos Davatzikos, PhD Johns Hopkins University 2003994874 Preclinical AD Consortium
Yong Fan, PhD Children's Hospital of Philadelphia 3200950819-XX CHOP Pediatric Center of Excellence in Nephrology
Terence Gade, MD, PhD JBS Science, Inc. R44CA165312-UP Development of a urine test for the early detection of liver cancer
James C. Gee, PhD Allen Institute for Brain Science 2017-0567 A Community Resource for Single Cell Data in the Brain
Mohamad Habes, PhD University of Washington UWSC10710 Atrial fibrillation burden, vascular disease of the brain MRI in MESA: MRI biomarker patterns for AD/ADRD
Joel S. Karp, PhD University of California, Davis 201501155-01 EXPLORER: Changing the Molecular Imaging Paradigm with Total Body PET
Joel S. Karp, PhD ECOG-ACRIN Medical Research Foundation, Inc. 1616 - 05 ECOG-ACRIN Operations Center
Despina Kontos, PhD Mayo Clinic Rochester UOP-225625-01 Radiomic phenotypes of breast parenchyma and breast cancer risk and detection
Despina Kontos, PhD ECOG-ACRIN Medical Research Foundation, Inc. U10CA180820-05-UPA12 ECOG-ACRIN Operations Center
David A. Mankoff, MD, PhD ECOG-ACRIN Medical Research Foundation, Inc. Ecog-ACRIN ECOG-ACRIN Operations Center
Chamith S. Rajapakse, PhD New York University 14-A1-00-001693 MRI of Proximal Femur Microarchitecture as a Biomarker of Bone Quality
Chamith S. Rajapakse, PhD New York University 16-A0-00-005518-01 Translation of Hip Microarchitectural Assessment Technology to the Clinic to Diagnose Glucocorticoid-Induced Osteoporosis
Chamith S. Rajapakse, PhD Temple University 262567-01 UPENN Correlation of Bone Strength with MR Imaging and Spectroscopic-Derived Parameters
Ravinder Reddy, PhD University of Miami SPC-000724 Development and Maintenance of Software for MR Spectroscopic Imaging
Ravinder Reddy, PhD Children's Hospital of Philadelphia 3258760720 Muscle Accrual and Function in Cystic Fibrosis-Impact of Glucose Intolerance
Mark Rosen, MD, PhD American College of Radiology 1672 ECOG-ACRIN-Based QIN Resource for Advancing Quantitative Cancer Imaging in Clinical Trials
Mitchell D. Schnall, MD, PhD, FACR ECOG-ACRIN Medical Research Foundation, Inc. U10CA180820-01-UPA1 ECOG-ACRIN Operations Center
Mitchell D. Schnall, MD, PhD, FACR ECOG-ACRIN Medical Research Foundation, Inc. 1UG1CA189828-01-UPA3 ECOG-ACRIN NCORP Research Base - CCDR
Mitchell D. Schnall, MD, PhD, FACR ECOG-ACRIN Medical Research Foundation, Inc. SUB TO 1UG1CA189828-01-UPA1 ECOG-ACRIN NCORP Research Base - CT
Mitchell D. Schnall, MD, PhD, FACR ECOG-ACRIN Medical Research Foundation, Inc. U24CA196172-01-UPA1 ECOG-ACRIN Biorepositories to support NCTN
Michael C. Soulen, MD Thomas Jefferson University 080-30000-S22601 2D and 4D Contrast-enhanced Ultrasound Evaluation of Hepatocellular Carcinoma Chemoembolization
Joel M. Stein, MD, PhD Columbia University 3 (GG009422 The Role of Place and Grid Cells in Human Spatial Navigation and Memory
Jayaram K. Udupa, PhD Albert Einstein College of Medicine, Inc. 311072Amend 3 A Computational Biomechanical Airway Model for Obese Children at Risk for OSAS
Jayaram K. Udupa, PhD Children's Hospital of Philadelphia RFRNT17002 Center for Thoracic Insufficiency Syndrome (CTIS) Frontier Program
Felix W. Wehrli, PhD Children's Hospital of Philadelphia 3207950619 Cerebral Anatomy, Hemodynamics and Metabolism In Single Ventricles: Relationship to Neurodevelopment
Paul A. Yushkevich, PhD Northern California Institute for Research and Education U19AG024904 Amend 2 Medial Temporal Lobe Subregion MRI Biomarkers for ADNI3

Foundation Grants FY18

PI Sponsor Fund Desc Title
Harrison Bai, MD RSNA Research & Education Foundation RF1802 Utilization of Deep Learning to Predict Characteristics and Treatment Response in Renal Tumors
Harrison Bai, MD Society of Interventional Radiology N/A Utilization of Deep Learning to Predict Characteristics and Treatment Response in Renal Tumors
Jamaal L. Benjamin, MD Society of Interventional Radiology N/A Understanding Epigenetic Alterations that Enable Hepatocellular Carcinoma Cell Survival Under Metabolic Stress
Bryan Chang, MD, PhD RSNA Research & Education Foundation RR1808 Tracking Engineered T Cell Therapies with an RNA-Based Reporter Gene
Tessa S. Cook, MD, PhD The Beryl Institute N/A Speak Wisely: Analyzing Patients’ Sentiments to Different Styles of Radiology Reports
Tessa S. Cook, MD, PhD Society of Imaging Informatics in Medicine N/A National Imaging Informatics Curriculum & Course
David P. Cormode, PhD Pennsylvania Breast Cancer Coalition PBCC Silver sulfide nanoparticles as low-cost, high contrast dual energy mammography contrast agents
Michael D. Farwell, MD American Association for Cancer Research SU2C-AACR-IRG-15-17 Imaging CAR T Cells with a Dual Function PET Reporter Gene
Terence Gade, MD, PhD Society of Interventional Radiology N/A CRISPR Based Genome Editing to Enable Functional Precision Medicine in Hepatocellular Carcinoma
Terence Gade, MD, PhD Society of Interventional Oncology N/A Characterization of the Immunobiologic Response Following Transarterial Chemoembolization (TACE) of Human Hepatocellular Carcinoma
Terence Gade, MD, PhD Society of Interventional Oncology N/A Targeting the Metabolic Stress Response in Hepatocellular Carcinoma
Junjian Huang MD Society of Interventional Radiology N/A A Double Blind Randomized Control Trial Evaluating Liposomal Bupivicaine to Perform a Superior Hypogastric Nerve Block for Uterine Artery Embolization
Maxim Itkin, MD Children's Hospital of Philadelphia 7227450000 Thoracic Duct-Lymphatic Center Project
Andrew D. Maidment, PhD, FAAPM Burroughs Wellcome Fund 1016451 ViCTRE - Virtual Clinical Trials in The Regulatory Environment
David A. Mankoff, MD, PhD Susan G. Komen Breast Cancer Foundation SAC130060 Molecular Imaging of Breast Cancer Metabolism to Predict In Vivo Cancer Behavior
Gregory J. Nadolski, MD RSNA Research & Education Foundation RSD1813 Clinically Relevant Point of Care Testing to Improve Quality of Solid Tumor Biopsies
Brian J. Park, MD Society of Interventional Radiology N/A Development, C=clinical Implementation, and Systematic Evaluation of 3D Holographic Visualization of Volume Rendering Techniques
Mark Rosen, MD, PhD American College of Radiology 1616 Imaging & Radiation Oncology Core - Philadelphia Imaging Core Lab Director
Ronnie A. Sebro, MD, PhD RSNA Research & Education Foundation RSCH1713 Integrated Biomarker PET/CT Imaging Trial for Assessing Hypoxia in Soft Tissue Sarcomas Using a Novel PET/CT Tracer
Mark A. Sellmyer, PhD Burroughs Wellcome Fund 1018469 Engineering Digital Logic for Imaging Cell-Cell Interactions
Mikhail Silk, MD RSNA Research & Education Foundation RR1868 Developing Tace 2.0: Targeting Hepatocellular Carcinoma Cells Through the Unfolded Protein Response, Hypoxia Inducible Factor and Autophagy Inhibition
Menekhem Muz Zviman, PhD Children's Hospital of Philadelphia 4260820620 Lymphatic Imaging and Intervention

Miscellaneous: DOD, Industry and State of Pennsylvania FY18

DOD

PI Sponsor Fund Desc Title
Raymond Acciavatti, PhD Army W81XWH1810082 Design of a 3D Mammography System in the Age of Personalized Medicine

INDUSTRY

PI Sponsor Fund Desc Title
Timothy W.I. Clark, MD Surmodics, Inc. SUR17-001 The Randomized And Controlled Noninferiority Trial to Evaluate Safety and Clinical Efficacy of the SurVeil™ Drug-Coated Balloon iN the Treatment of Subjects with Stenotic Lesions of the Femoropopliteal Artery Compared to the Medtronic IN.PACT® Admiral® Drug-Coated Balloon TRANSCEND Study
Michael D. Farwell, MD ImaginAb, Inc. Farwell-2015-22M2C-01 A Phase I Study of Positron Emission Tomography (PET/CT) with 89Zr-Df-IAB22M2C in Patients with Selected, Metastatic Solid Malignancies (Non Small Cell Lung Cancer (NSCLC), Small Cell Lung Cancer (SCLC), Squamous Cell Carcinoma Head and Neck (SqCCHN), Melanoma, Merkel Cell Tumor, Renal, Bladder, Hepatocellular, Triple Negative Breast, or Gastroesophageal Cancer) or Hodgkin's Lymphoma
Can Ficicioglu, MD, PhD REGENXBIO, Inc. Ficicioglu-RGX-111-002 A Phase I Multicenter, Open-Label Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of Intracisternal RGX-111 Gene Therapy in Subjects with Mucopolysaccharidosis Type I
Maxim Itkin, MD Guerbet LLC I002672 Intralymphatic lipiodol injection: effect on the microscopic changes in lymph nodes and ducts and pulmonary functions
Joel S. Karp, PhD Siemens Medical Solutions USA, Inc. A1005062 Development of Image Reconstruction Methods in PET
Suyash Mohan, MD Novocure Ltd. N/A Evolving Landscape in the Management of Glioblastoma: From Temozolomide to Tumor Treating Field
Michael C. Soulen, MD Teclison LTD Soulen-LT006 TATE Versus TACE, An Open-Label Randomized Study Comparing Transarterial Tirapazamine Embolization Versus Transarterial Chemoembolization In Intermediate Stage Hepatocellular Carcinoma
Robert H. Vonderheide, MD, DPhil Celgene Corporation Celgene Corporation New Tools for Imaging the Immune system in the Setting of Cancer Immunotherapy

STATE OF PA FUNDING

PI Sponsor Fund Desc Title
David A. Mankoff, MD, PhD American College of Radiology SUB TO 4100068708 CURE 12 Improving Quantitative Imaging Biomarker Methods to Accelerate the Development of Effective Cancer Therapies
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