Sharing the outcomes of our research with the academic community has long been a source of pride at Penn Medicine’s Department of Radiology. The Department publishes numerous articles in prominent scientific journals (see below) as well as serving on a number of their editorial boards.
Selected Publications 2019-2020
Association of cerebral white matter changes and blood pressure control
Nasrallah IM, Pajewski NM, Auchus AP, Chelune G, Cheung AK, et al. Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions: SPRINT MIND Investigators for the SPRINT Research Group. JAMA. 2019 Aug 13;322(6):524-534. pubmed.ncbi.nlm.nih.gov/31408137/
Consensus guidelines on CT interpretation for COVD-19
Simpson S, Kay FU, Abbara S, Bhalla S, Chung JH, et al. Radiological Society of North America Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19. Endorsed by the Society of Thoracic Radiology, the American College of Radiology, and RSNA. J Thorac Imaging. 2020 Apr 28. DOI: 10.1148/ryct.2020200152
Unusual brain findings in US State Department personnel
Verma R, Swanson RL, Parker D, Ould Ismail AA, Shinohara RT, et al. Neuroimaging Findings in US Government Personnel With Possible Exposure to Directional Phenomena in Havana, Cuba. JAMA. 2019 Jul 23;322(4):336-347. pubmed.ncbi.nlm.nih.gov/31334794/
Impact of breast tomosynthesis on breast screening performance parameters
Conant EF, Barlow WE, Herschorn SD, Weaver DL, Beaber EF, et al. Association of Digital Breast Tomosynthesis vs Digital Mammography With Cancer Detection and Recall Rates by Age and Breast Density. JAMA Oncol. 2019 May 1;5(5):635-642. pubmed.ncbi.nlm.nih.gov/30816931/
ECOG-ACRIN multicenter study of abbreviated breast MRI
Comstock CE, Gatsonis C, Newstead GM, Snyder BS, Gareen IF, et al. Comparison of Abbreviated Breast MRI vs Digital Breast Tomosynthesis for Breast Cancer Detection Among Women With Dense Breasts Undergoing Screening. JAMA. 2020 Feb 25;323(8):746-75. pubmed.ncbi.nlm.nih.gov/32096852/
Nature paper on microbial flora metabolism
Zhao S, Jang C, Liu J, Uehara K, Gilbert M, et al. Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. Nature. 2020 Mar;579(7800):586-591. pubmed.ncbi.nlm.nih.gov/32214246/
Novel MR methods for imaging glucose kinetics
Rich LJ, Bagga P, Wilson NE, Schnall MD, Detre JA, Haris M, Reddy R. 1H magnetic resonance spectroscopy of 2H-to-1H exchange quantifies the dynamics of cellular metabolism in vivo. Nat Biomed Eng. 2020 Mar;4(3):335-342. pubmed.ncbi.nlm.nih.gov/31988460/
First human studies of the whole-body PET scanner, PennPET Explorer
Pantel AR, Viswanath V, Daube-Witherspoon ME, Dubroff JG, Muehllehner G, et al. PennPET Explorer: Human Imaging on a Whole-Body Imager. J Nucl Med. 2020 Jan;61(1):144-151. DOI: 10.2967/jnumed.119.231845
Optical imaging collaboration for image-guide surgery (with Penn Medicine Department of Surgery)
Predina JD, Newton AD, Corbett C, Shin M, Sulfyok LF, et al. Near-infrared intraoperative imaging for minimally invasive pulmonary metastasectomy for sarcomas. J Thorac Cardiovasc Surg. 2019 May;157(5):2061-2069. pubmed.ncbi.nlm.nih.gov/31288365/
Image analytics toolkit, basis for a collaboration with the ACR and Intel
Fathi Kazerooni A, Akbari H, Shukla G, Badve C, Rudie JD, et al. Cancer Imaging Phenomics via CaPTk: Multi-Institutional Prediction of Progression-Free Survival and Pattern of Recurrence in Glioblastoma. CO Clin Cancer Inform. 2020 Mar;4:234-244. DOI: 10.1200/CCI.19.00121
Imaging a new therapeutic target (PARP) in breast cancer
McDonald ES, Doot RK, Pantel AR, Farwell MD, Mach RH, Maxwell KN, Mankoff DA. Positron Emission Tomography Imaging of Poly-(Adenosine Diphosphate-Ribose) Polymerase 1 Expression in Breast Cancer: A Nonrandomized Clinical Trial. JAMA Oncol 2020 Jun 1;6(6):921-923. pubmed.ncbi.nlm.nih.gov/32297911/
Penn Radiology Research is widely published in the following journals: