Department of Radiology

Cardiac Function

SPAMM (SPAtial Modulation of Magnetization)

Simulated 3D Tag Data Set

Simulated 3D Tag Data Set

SPAMM tagged short axis

SPAMM tagged short axis of an anterior infarct showing myocardial thinning and LV dilitation

Spatial Modulation of Magnetization (SPAMM) Analysis

Flow chart of 3D strain computation

Flow chart of 3D strain computation from deformed synthetic image volume.

Applications

Applications of SPAMM Imaging - Infarct K9 Cardiomyoplasty analyzed with 2D optical flow

Displacement Map of Cardiomyoplasty

Displacement Map of Cardiomyoplasty

Left: Nonstimulated demonstrates uniform displacement over the entire left ventricle.

Right: Muscle stimulation resulted in an increase in displacement in the anterior region of the left ventricle.

Maximum Principal Strain Lambda 1

Maximum Principal Strain Lambda 1

Left: Uniform strain pattern in the nonstimulated myoplasty.

Right: Stimulation increased the principle strain in the anterior region indicating an improvement in function.

3D Surface Modeling

3D Surface Modeling

3 Month Post-MI, Control (left) and Treated (right).

Border Zone Analysis Performed Using 2D Optical Flow

Border Zone Analysis

Left: Created anterior infarct.

Right: Placed titanium markers at BZ.

spammapp2

Short axis image of an ovine infarct model eight weeks post infarct with marker indicating border zone region. The border zone was considered to be the adjacent myocardium within a 20 degree arc of the marker.

Systolic Radial Strain Dynamics

Systolic Radial Strain Dynamics

In the non-infarct border zone, strain increased linearly from end-diastole to end-systole. Strain increased during isovolumic contraction in the control group but decreased thereafter. The CSD strain increased then remained constant and dramatically increased during late ejection.

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