One of our most exciting current avenues of research is the development of novel lipoprotein-based nanoplatforms for the delivery of diverse therapeutic/diagnostic agents. We also design "PDT beacons”, activatable photodynamic therapy agents that can be tailored to report their own therapeutic outcome in vivo. Our development of smarter probes for imaging and PDT will hopefully lead to further advancements in both cancer detection and treatment.
Members of our lab have varying backgrounds and come from all over the world. Currently, we are collaborating with several groups, both inside and outside of the University. Our lab is located in the 1958 wing of the Chemistry Building at the University of Pennsylvania.
Above are images of photosensitizer delivery to folate-positive tumor cells. The tumor is clearly visible within 24 hrs.