Department of Radiology

The goal of the Functional and Metabolic Imaging Group (FMIG) is the development and application of novel hyperpolarized MRI techniques capable of diagnosing a variety of pulmonary and metabolic disorders.

Specifically, our research activities at FMIG is divided into four general branches:

  1. The development of novel imaging techniques for the quantitative assessment of pulmonary structure and function through use of hyperpolarized gas (3He and 129Xe).
  2. Development of real-time metabolic imaging techniques to investigate the use of hyperpolarized 13C-labeled metabolites (e.g. [1-13C]pyruvate) for imaging lung perfusion and pulmonary pH, as well as detecting aberrant metabolism, which is a key pathological indication for a number of disease states, including cancer in other organs including liver, brain and heart.
  3. Study of the Dynamic Nuclear polarization (DNP) and Optical pumping technologies and polarization dominant relaxation mechanisms with the aim of increasing polarization levels as well extension of longitudinal relaxation.
  4. Implementation of rapid imaging pulse sequences and their applications in hyperpolarized MRI.

Learn more about the FMIG

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