Division of Hematology and Oncology

The GI Cancer Research program researches and develops new and effective therapies for gastrointestinal cancers.

The Medical Oncology Gastrointestinal Malignancies Research Program provides compassionate, multidisciplinary care that is informed by research to develop the most effective therapies for gastrointestinal malignancies including, esophageal, stomach, colon and rectal, pancreatic, liver and bile duct cancers, and neuroendocrine tumors.

Penn physicians conduct a variety of clinical research studies in close collaboration with other departments/divisions including:

  • Colorectal surgery 
  • Gastroenterology 
  • Radiation oncology 
  • Gastrointestinal surgery 
  • Interventional radiology
  • Penn Centers for Pancreatic Cancer and Liver Cancer 
  • Surgery

Penn physicians also conduct clinical research and other investigations to improve the ability to diagnose and treat patients with all types of gastrointestinal malignancies. It is through such research that clinicians improve current modalities and develop future cancer treatments and care.

These studies include:

  • Assessment of new therapies for all stages of gastrointestinal malignancies, including studies combining surgery, radiation and other local therapies and chemotherapy. 
  • Assessment of new experimental agents for the treatment of patients with advanced gastrointestinal malignancies, including phase 1 clinical trials. 
  • Quality-of-life studies. 
  • Analysis of tissue, blood, and tumor samples to better understand the biology of the malignancies and relationship to patient outcomes.

Patients with gastrointestinal cancers may be asked to participate in a variety of research studies.

Medical oncologists involved in the management of gastrointestinal cancer include:

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