Division of Gastroenterology

Grant number: P30-DK050306

The Center's research and membership are organized according to three themes or affinity groups:

  1. Developmental biology and regenerative medicine
    Christopher Lengner, PhD and Ken Zaret, PhD
    Program Co-Leaders
  2. Microbe and host immune responses program
    Frederic D. Bushman, PhD, Kyong-Mi Chang, MD and E John Wherry, PhD
    Program Co-Leaders
  3. Cell growth and differentiation
    Sandra Ryeom PhD and Ben Stanger MD, PhD
    Program Co-Leaders

***Center Member Application***

Center Members

  • Ravi Amaravadi, MD
    Associate Professor of Medicine
    Department of Hematology, Oncology
  • Igor Brodsky, PhD
    Assistant Professor of Pathobiology
    Department of Pathobiology
  • Frederic Bushman, PhD
    William Maul Measey Professor in Microbiology
    Department of Microbiology
  • Rotonya Carr, MD
    Assistant Professor of Medicine
    Division of Gastroenterology
  • Russell Carstens, MD
    Associate Professor of Medicine
    Division of Renal Electrolyte
  • Kyong-Mi Chang, MD
    Associate Chief of Staff for Research and Development
    Corporal Michale J. Crescenz VA Medical Center
    Professor of Medicine
    Associate Dean for Research
    Division of Gastroenterology
  • Youhai Chen, MD, PhD
    Professor of Pathology and Laboratory Medicine
    Department of Pathology and Laboratory Medicine
  • Yongwon Choi, PhD
    Leonard Jarett Professor of Pathology and Laboratory Medicine
    Department of Pathology and Laboratory Medicine
  • Garret FitzGerald, MD
    Chair of Systems Pharmacology and Translational Therapeutics
    McNeil Professor in Translational Medicine and Therapeutics
    Department of Pharmacology
  • Serge Fuchs, MD, PhD
    Professor of Cell Biology
    Director, Mari Lowe Center for Compartive Oncology
    Department of Biomedical Sciences
    School of Veterinary Medicine
  • Dmitry Gabrilovich, MD, PhD
    Christopher M. Davis Professor
    Professor and Program Leader, Translational Tumor Immunology Program
    The Wistar Institute
  • Donna George, PhD
    Associate Professor of Genetics
    Department of Genetics
  • George Hajishengallis, DDS, PhD
    Thomas W. Evans Centennial Professor
    Department of Microbiology
  • Robert Heuckeroth, MD, PhD
    Irma and Norma Braman Endowed Chair in Pediatric Motility Disorders
    Professor of Pediatrics
    Children's Hospital of Philadelphia
  • Xianxin Hua, PhD
    Professor of Cancer Biology
    Department of Cancer Biology
  • Christopher Hunter, BSc, PhD
    Mindy Halikman Heyer Distinguished Professor of Pathology
    School of Veterinary Medicine
  • F. Bradley Johnson, MD, PhD
    Associate Professor of Pathology and Laboratory Medicine
    Department of Pathology and Laboratory Medicine
  • Klaus Kaestner, PhD
    Suor Butterworth Professor in Genetics
    Department of Genetics
  • David Kaplan, MD, MSc
    Assistant Professor of Medicine
    Division of Gastroenterology
  • Jonathan Katz, MD
    Associate Professor of Medicine
    Director, Molecular Pathology and Imaging Core
    Division of Gastroenterology
  • Peter Klein, MD, PhD
    Professor of Medicine
    Department of Cell and Developmental Biology
  • Mitchell Lazar, MD, PhD
    Willard and Rhoad Ware Professor in Diabetes and Metabolic Diseases
    Chief, Division of Endocrinology, Diabetes, and Metabolism
  • Christopher Lengner, BS, PhD
    Associate Professor
    Department of Biomedical Sciences
    School of Veterinary Medicine
  • James D. Lewis, MD, MSCE
    Professor of Medicine
    Division of Gastroenterology
  • Stephen Liebhaber, MD
    Profess or Genetics
    Director, Genetically Modified Mouse Core
    Department of Genetics
  • Edward E. Morrisey, PhD
    Robinette Foundation Professor of Cardiovascular Medicine
    Professor of Medicine and Cell and Developmental Biology
    Department of Cell and Developmental Biology
  • Hiroshi Nakagawa, MD, PhD
    Research Associate Professor of Medicine
    Associate Director, Cell Culture and iPS Core
    Division of Gastroenterology
  • Michael Pack, MD
    Professor of Medicine and Cell and Developmental Biology
    Division of Gastroenterology
  • Arjun Raj, PhD
    Assistant Professor of Bioengineering
    Department of Bioengineering
  • K. Rajender Reddy, MD
    Ruimy Family President's Distinguished Professor of Medicine
    Division of Gastroenterology
  • Patrick Seale, PhD
    Assistant Professor of Cell and Developmental Biology
    Department of Cell and Developmental Biology
  • George Shaw, MD, PhD
    Professor of Medicine and Microbiology
    Division of Hematology, Oncology
  • Sunil Singhal, MD
    William M. Measey Associate Professor
    Division of General Thoracic Surgery
  • Raymond E. Soccio, MD, PhD
    Assistant Professor of Medicine
    Department of Cell and Molecular Biology
  • Ben Z. Stanger, MD, PhD
    Professor of Medicine
    Division of Gastroenterology
  • Doris Stoffers, MD, PhD
    Professor of Medicine
    Division of Endocrinology, Diabetes and Metabolism
  • Kathleen E. Sullivan, MD, PhD
    Professor of Pediatrics
    Division of Allergy and Immunology
    Children's Hospital of Philadelphia
  • Katalin Susztak, MD, PhD
    Professor of Medicine and Genetics
    Department of Cell and Molecular Biology
  • Andrei Thomas-Tikhonenko, PhD
    Professor of Pathology and Laboratory Medicine
    Pathology and Laboratory Medicine
    Children's Hospital of Philadelphia
  • Patrick Viatour, PharmD, PhD
    Assistant Professor of Laboratory Medicine
    Department of Pathology and Laboratory Medicine
    Children's Hospital of Philadelphia
  • Robert Vonderheide, PD, DPhil
    Hanna Wise Professor in Cancer Research
    Department of Cancer Biology
  • Andrew D. Wells, PhD
    Associate Professor of Pathology and Laboratory Medicine
    Department of Pathology and Laboratory Medicine
  • Rebecca G. Wells, MD
    Professor of Medicine
    Division of Gastroenterology
  • E. John Wherry, PhD
    Richard and Barbara Schiffrin President's Distinguished Professor of Microbiology
    Chair Department of Systems Pharmacology and Translation Therapeutics
  • Gary D. Wu, MD
    Ferdinand G. Weisbrod Professor in Gastroenterology
    Director, Host-Microbial and Repository Core
    Division of Gastroenterology
  • Xiaolu Yang, PhD
    Professor of Cancer Biology
    Department of Cancer Biology
  • Kenneth Zaret, PhD
    Joseph Leidy Professor of Cell and Development Biology
    Department of Genetics
  • Jun Zhu, PhD
    Associate Professor of Microbiology
    Department of Microbiology

Pilot and Feasibility Grant Program

Grant number: P30-DK050306
Purpose and Research Focus

The purpose of the Center is to unite investigators with interests in digestive and liver physiology and disease and to stimulate others in the biomedical community to enter this area of research. One of the most important aspects of this effort is the funding of Pilot/Feasibility Projects.

The Pilot/Feasibility Project should be related to the focus of the Center, which encompasses molecular studies on the biology or disease of the alimentary tract, pancreas, and liver. Relevant investigations include those in developmental biology, nutrition, regulation of gene expression, growth, differentiation and carcinogenesis, the biology of stem cells, molecular genetics, gene therapy, and immunology, including growth factors and cytokines.

Eligibility

All faculty members of the University scientific community who meet the eligibility requirements below are invited to submit proposals. Applicants must be U.S. citizens or have permanent visas.

  • New investigators who have never held extramural support
  • (R01, P01).
  • Established investigators in other areas of biomedical research who wish to apply their expertise to a problem in digestive and liver disease.
  • Established digestive and liver investigators who wish to study an area that represents a significant departure from currently funded work.
Pilot project awardees are eligible for two years of funding; renewals are evaluated competitively.
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