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Trial Contacts

I3 - Research Coordinator: 215-360-0904

PIANO - Research Coordinator:



Primary Investigator: Faten Aberra, MD, MSCE

Research Coordinator: Alice Alderson




A 5-year Longitudinal Observational Study of Patients Undergoing Therapy for Inflammatory Bowel Disease (Target-IBD)

The goals of this study are to collect information on patients with IBD to determine the natural course of the disease and to determine how procedures or treatments that may be recommended by your doctors may affect IBD and general health. This research study is intended to observe any treatment for IBD in a large number of people in a "real life" setting. Researchers are interested in observing how these treatments, lifestyle changes, and counseling work in patients who are treated by their doctors in routine practice. Information about which treatments are being used and responses to these treatments will be collected to help researchers better understand how IBD is managed.


Inclusion Criteria:

1) Adults and children (age 2 or older) with a diagnosis of Crohn's Disease (CD), Ulcerative colitis (UC), or Indeterminate colitis (IBDU) having been prescribed any IBD treatment (initial or subsequent) outside of a clinical trial.

2) Have plans for future visits at the site for continued management of IBD.

3) Must be seen within the Penn Health System.

Exclusion Criteria:

1) Inability to provide written consent/assent

2) Being enrolled in any interventional study or trial for IBD treatment. Note: Patient may be enrolled in other registries or studies where IBD treatment outcomes are observed and/or reported (such as center-based registries).

3) Prior total abdominal colectomy for UC or IBDU.


Inflammatory Bowel Disease and Neonatal Outcomes


A translational clinical and tissue database study.

Actively enrolling all Crohn's disease and Ulcerative Colitis patients seen within the University of Pennsylvania Health System.  The aim is to understand abnormalities in the immune system and other factors that impact IBD.


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