The son of Lithuanian immigrants, Irving Shapiro (1916-2001) graduated from the University of Minnesota Law School in 1941 and held a variety of government positions during and after World War II. In 1948, as a lawyer for the Justice Department, he won his first case before the Supreme Court. Three years later he joined DuPont's legal team. Mr. Shapiro grew intimately acquainted with the company during the lengthy General Motors-DuPont antitrust suit, and as the chief architect of the settlement won the trust of the du Pont family. Shapiro became assistant general counsel in 1965 and five years later was appointed to the Executive Committee. In July 1973 he became vice chairman, preparing the way for his succession to becoming Chairman and CEO in December 1973. Mr. Shapiro steered DuPont successfully through many issues in the 1970s. Under Mr. Shapiro's stewardship, DuPont expanded its overseas operations. Mr. Shapiro retired in 1981 but continued to practice law in Wilmington and provide counsel to DuPont into the 1990s.
Irving Shapiro, and his wife, Charlotte Shapiro, established in 1998 an annual lecture to highlight distinguished researchers within the Division of Gastroenterology at the University of Pennsylvania.
The following is a list of the speakers of the Shapiro Lectureship:
Anil K. Rustgi, MD
University of Pennsylvania
Ken Kinzler, PhD
Johns Hopkins University
"Pathogenesis of Colon Cancer"
George Michaelopoulos, MD, PhD
University of Pittsburgh
Montgomery Bissell, MD
University of California at San Francisco
Stefan Targan, MD
Cedars Sinai Hospital, UCLA
"Mucosal specific mechanisms of IFN-g regulation"
Fiona Powrie, PhD
University of Oxford
"Control of immune pathology by regulatory T cells"
Hans Clevers, PhD
Linheng Li, PhD
Stowers Institute for Medical Research
"Stem cell regulation in intestinal and hematopoietic systems"
Matthew Meyerson, MD, PhD
Harvard Medical School
"Genomic studies of human cancer"
Brigid L.M. Hogan, PhD, FRS
"Lung stem cells in development and repair"
Mina J. Bissell, PhD
Lawrence Berkeley National Laboratory
"The importance of tumor microenvironment in initiation, promotion, and therapy of cancer"
Michael Karin, PhD
Tumor Growth, Invasion & Metastasis Program
University of California, San Diego
"Inflammation, metabolism, aging and cancer: dangerous liaisons"
Eric Fearon, M.D.. PhD
Chief, Molecular Medicine & Genetics
Emanuel N. Maisel Professor of Oncology
Professor of Internal Medicine, Human Genetics & Pathology
Associate Director for Basic Science
University of Michigan, Comprehensive Cancer Center
"The use of mouse models to explore the molecular pathogenesis of colorectal cancer"
Carol Prives, PhD
Da Costa Professor of Biology
Department of Biological Sciences
"Lessons learned from studying the p53 tumor suppressor protein"
Andrea Califano, PhD
Professor of Systems Biology
Chief, Division of Biomedical Informatics
Director, Columbia Initiative in Systems Biology
Director, Center for the Multiscale Analysis of Genomic Networks
Associate Director for Bioinformatics, Herbert Irving Comprehensive Cancer Center
"Analysis of gene regulatory networks elucidates master regulators of tumor initiation, progression, and chemosensitivity"
D. Brent Polk, MD
Professor and Chair, Department of Pediatrics
Professor of Biochemistry and Molecular Biology
Physician-in-Chief and Vice President of Academic Affairs, CHLA
Director, The Saban Research Institute
"Good fences make good neighbors: Repair and regeneration of intestinal epithelium across space and time"
Richard Peek, MD
Director, Division of Gastroenterology
Professor of Pathology, Microbiology and Immunology
Mina Cobb Wallace Chair in Immunology
"Molecular underpinnings and tragic triangulations of helicobacter pylori-onduced gastric cancer"
"Intermediate filaments of digestive organs: Pathophysiologic and Therapeutic Perspectives"
Bishr Omary, MD, PhD
Executive Vice Dean for Research
Chief Scientific Officer
H. Marvin Pollard Professor of Gastroenterology
Professor of Molecular and Integrative Physiology and Internal Medicine
University of Michigan Medical School