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Uterine Cancer Diagnostic Tools and Tests

Our cancer specialists at Penn Medicine's Abramson Cancer Center are highly experienced in using the most advanced techniques for diagnosing uterine cancer and are actively researching better and more precise ways to detect cancer.

Diagnosing Uterine Cancer

Uterine cancer, or cancer in the lining of the uterus, may be detected during a pelvic exam, including a Pap test.

During the exam, a Penn Medicine gynecologist examines the vagina, uterus, bladder and rectum. Blood and urine tests may also be ordered. Changes in the size, shape, or feel of the lining of the uterus or surrounding structures may be seen when the disease is more advanced.

Women experiencing signs and symptoms of uterine cancer or women who have had an abnormal Pap test result test may need further testing to diagnose uterine cancer.

Diagnostic testing may include:

  • Transvaginal ultrasound. A type of ultrasound used to look at the reproductive organs, including the uterus, ovaries, cervix, and vagina. Transvaginal means across or through the vagina.
  • Biopsy. A biopsy is a diagnostic surgical procedure in which a sample of tissue from the uterine lining is removed and examined under a microscope. In some cases a dilation and curettage (D and C) is necessary to confirm the diagnosis.

Navigating a uterine cancer diagnosis and treatment options can be difficult. If you receive a cancer diagnosis, our cancer nurses are available and ready to help connect you with the right physician.

To connect with a cancer nurse at Penn Medicine, you should call 800-789-7366 (PENN).