The following tests and procedures may be used to diagnose chronic myelomonocytic leukemia (CMML):
- Medical history
- Physical exam
- Complete blood count in which a sample of blood is drawn and checked for the number of red blood cells, platelets, and white blood cells.
- Genetic sequencing through Penn Medicine's Center for Personalized Medicine that will identify genomic alterations so clinicians can design and implement optimal treatment plans.
- Peripheral blood smear: A procedure in which a sample of blood is checked to see how the blood appears under a microscope, and if there are blasts.
- Blood chemistry studies
- Bone marrow biopsy
- Cytogenetic analysis
- Specific genetic mutation testing