The Basser Center Monthly Seminar Series is held at noon on the first of the month in the Smilow Translational Research Center. This internal series is open to Penn faculty and staff. The Basser Center also sponsors a scientific symposium.
For more information on seminars and symposia, email Basser Administrative Coordinator, Trish Palen.
March 3, 2017, 12:00-1:00 pm to be held in SCTR 09-146AB
Mehran Makvandi, PARP-1 dynamics explored through PET imaging in ovarian cancer as a biomarker of DNA damage and treatment response
April 7, 2017, 12:00-1:00 pm to be held in SCTR 09-146AB
May 5, 2017
Seminar cancelled due to Basser Symposium
February 3, 2017, 12:00-1:00 pm to be held in SCTR 09-146AB
Lin Zhang, MD, Combination therapy to overcome PARPi resistance in ovarian and breast cancer
January 6, 2017, 12:00-1:00 pm To be held in SCTR 09-146AB
Ken Zaret, PhD Reprogramming Cancer to Detect Early Progression Biomarkers
December 2, 2016
Ben Stanger, MD, PhD “Using Lineage Tracing to Examine Timing and Mechanisms During Metastatic Spread"
November 4, 2016
Angela Bradbury, MD "Innovative Delivery Models for Dissemination of Genetic Services in the Era of Precision Medicine"
October 7, 2016
Kara Maxwell, MD, PhD "The Relationship of Loss of Heterozygosity at the BRCA Locus with Signatures of BRCA Deficiency in Tumors and Clinical Outcomes"
September 9, 2016
Susan Domchek, MD "Update on PARP Inhibitors in BRCA-Associated Cancers"
July 15, 2016
Robert Vonderheide, MD, DPhil and David Weiner, PhD "Prospect of a Vaccine to Prevent BRCA1/2 Cancers"
June 3, 2016
Cynthia Otto, DVM, PhD, Janos Tanyi, MD, PhD, George Preti, PhD, Charlie Johnson, PhD, Jody Piltz-Seymour, MD
"Sniffing Out Ovarian Cancer: An Interdisciplinary Approach to Early Detection"
May 6, 2016
Eric Brown, PhD "Exploiting Replication Stress as a Cancer Therapeutic Target"
April 1, 2016
Robert Burger, MD "Neo-Adjuvant Chemotherapy as a Platform for Screening Activity of Ovarian Cancer Therapeutics"
March 4, 2016
Jason Moore, PhD "Penn Institute for Biomedical Informatics"
February 4, 2016
Andy Minn, MD, PhD "Breast Cancer Progression and Therapy Response Driven by Viral Mimicry"
January 8, 2016
Jennifer Morrissette, PhD "The Center for Personalized Diagnostics: Clinical Next Generation Sequencing"
December 4, 2015
Garrett Brodeur, MD (CHOP) "Cancer Predisposition Program at CHOP”
November 6, 2015
Roger Greenberg, MD, PhD “Alternative mechanisms of homologous recombination and resistance to PARP inhibitors"
October 2, 2015
Despina Kontos, PhD “Quantitative assessment of Background Parenchymal Enhancement in breast MRI as a predictor of response to Risk-Reducing Salpingo-Oophorectomy in BRCA1/2 carriers”
September 11, 2015
Judith Balmana, MD (Visiting Scholar – Vall d’Hebron Institute Oncology, Barcelona) – “Setting Up Multiplex Panel Testing for Hereditary Cancer Under a National Health System”
July 10, 2015
Fiona Simpkins, MD - “Novel Strategies to Personalize Therapy in Ovarian Cancer: From the Bench to the Bedside”
June 5, 2015
Kara Maxwell, MD, PhD - "The Genomic Landscape of BRCA1/2-associated Breast and Ovarian Tumors"
May 8, 2015
Angela Bradbury, MD - "Utilizing Telemedicine to Expand Access to BRCA1/2 Testing in Community Practices"
April 3, 2015
Ron Drapkin, MD, PhD - "Looking Down the Barrel of a Tube for the Origins of Ovarian Cancer"
March 6, 2015
Robert Mach, PhD - "New Directions for Imaging Breast Cancer with PET"
February 6, 2015
Susan Domchek, MD - "PARP Inhibitor Approval in Advanced Ovarian Cancer: Where do we go from here?"
January 9, 2015
Robert H. Vonderheide, MD, DPhil - "Prospects of Immune Prevention of BRCA1/2 Cancer"
December 5, 2015
Roger A. Greenberg, MD, PhD - "Using Mice to Understand BRCA Function"
November 7, 2014
Benjamin Garcia, PhD - "Quantitative Proteomics for Analyzing Cellular Function"
October 3, 2014
Andy Minn, MD, PhD - "Targeting and Function of Pathways Regulating Breast Cancer Treatment Resistance"
September 5, 2014
Erica Carpenter, MBA, PhD - "Circulating Tumor Material and Noninvasive Personalized Diagnostics: Recent Developments and Future Directions"
July 11, 2014
Kate Nathanson, MD - "A review of massively parallel sequencing and how to use the data generated"
June 6, 2014
Lin Zhang, MD - "Novel approaches to treating and understanding BRCA2 - related ovarian cancer using the zebrafish"
Michael A. Pack, MD - "A clinically guided genomic approach identifies the BRCAness of breast and ovarian cancer"
May 2, 2014
Eric Brown, PhD - "ATR-CHK1 Pathway inhibition as a treatment for BRCA1/2 -deficient cancers"
David Weiner, PhD - "Developing a DNA immune therapy target hTERT: prospect of immunoprevention of BRCA1/2 related cancers"
April 4, 2014
Clarisa Gracia, MD, MSCE - "Studying Fertility in Cancer Survivors and BRCA Carriers"
Daniel Powell PhD - "Redirected T cells for the Treatment of BRCA-associated Cancers"
March 7, 2014
Despina Kontos, PhD: "Breast DCE-MRI biomarkers for risk-reduction management of BRCA1/2 carriers"
Raymond J. Acciavatti, PhD: "Design of a Next-Generation Tomosynthesis System"
February 7, 2014
C. Neill Epperson, MD: "Impact of Natural and Surgical Menopause on Mood and Cognition"
Ben Stanger, MD, PhD: "Pancreatic Cancer and BRCA2"
January 3, 2014 - Event canceled due to weather.
David Weiner, PhD: "Developing a DNA immune therapy target hTERT: prospect of immunoprevention of BRCA1/2 related cancers"
December 6, 2013
Kate Nathanson, MD: "Somatic mutations in BRCA1/2 associated tumors"
Tim Rebbeck, PhD: "Mutation-specific risks in BRCA1/2 mutations carriers"
November 1, 2013
Andy Minn, MD, PhD: "Tumor and stroma pathways regulating breast cancer treatment resistance"
Andrea Facciabene, PhD: "Targeting the vasculature, tumor endothelial marker1 HLA-A2 epitopes mapping"
October 4, 2013
Susan Domchek, MD: "Update on PARP inhibitors in BRCA1/2 mutation carriers"
Angela Bradbury, MD: "The COGENT study: Communication of Genetic Test results by Telephone"
September 6, 2013
Katie Schmitz, PhD, MPH: "Dose response effects of exercise training on endogenous hormones in high risk women: The WISER Sister Trial"
Roger Greenberg, MD, PhD: "Chromatin Determinants of BRCA Function"
July 12, 2013
Shridar Ganesan, MD, PhD (UMDNJ) - "BRCA1, 53BP1 and PARP: DNA Repair Choice and Chemosensitivity".
June 7, 2013
Eric Brown, PhD: "Regulation of Replication Fork Stability by Aurora A-PLK1 and RNF4"
Angie DeMichele, MD, MSCE: "The 2-PREVENT Breast Cancer Translational Center of Excellence (TCE)"
May 3, 2013
Ramin Shiekhattar, PhD (Wistar Institute): "Genome-wide Analysis of BRCA Genes Reveals New Functions"
April 5, 2013
Kate Nathanson, MD: "Somatic Genetics and Genomics of BRCA1/2 Associated Breast and Ovarian Cancers"
Lin Zhang, MD: "Non-coding RNA in Breast and Ovarian Cancers"
March 1, 2013
David Mankoff, MD, PhD: "Breast Cancer Molecular Imaging"
Despina Kontos, PhD: "The Role of Breast MRI as a Biomarker for Guiding Risk-Reduction Interventions in BRCA1/2 Carriers"
February 1, 2013
Angela Bradbury, MD: "REACH: Research to Evaluate Adolescents and Communication of Hereditary Risk"
Andy Minn, MD, MPH: "Regulation and Function of Interferon-Stimulated Genes that Promote DNA Damage Resistance in Triple Negative and BRCA1 mutant Breast Cancer"
January 4, 2013
Andy Rhim, MD: "Using GEDI to Detect Circulating Epithelial Cells"
Chunsheng Li, PhD: "Development of Molecular Imaging of Tumor Vasculature for the Early Detection of Hereditary Ovarian and Breast Cancer"
December 7, 2012
Tim Rebbeck, PhD: "Why Do BRCA1/2 Confer Breast Cancer in Some Women and Ovarian Cancer in Others?"
Kara Maxwell, MD, PhD: "A Case of an Adult with Biallelic BRCA2 Mutations and an Atypical Phenotype"
November 2, 2012
Roger Greenberg, MD, PhD: "Identification of BRCAness"
Susan M. Domchek, MD: "Biallelic Deleterious BRCA1 Mutations in a Woman with Early-Onset Ovarian Cancer"
October 5, 2012
Andrea Faccibene, PhD: "Development of Vaccine Targeting the Tumor Vasculature for the Prevention of BRCA-deficient Tumors"
Susan Domchek, MD: "Cancer Risk Evaluation Program: Current and Future Biobank"