Our Mission

To use cutting edge research in basic and clinical sciences to advance the care of individuals living with BRCA1 and BRCA2 mutations.

The Basser Center infuses powerful resources to study BRCA1 and BRCA2 from multiple perspectives. Committed to building partnerships with national and international research and advocacy groups, the Center strives to better serve those facing hereditary breast and ovarian cancer.

The Center aims to promote research on:

Biology of BRCA1 and BRCA2

  • Understand the biology of BRCA1/2 cancers to improve diagnosis and treatment
  • Investigate genetics of BRCA-related tumors to understand how cancer develops and responds to therapies
  • Use new technologies to discover novel therapeutic strategies

Communication, Outreach and Risk Assessment

  • Increase identification of BRCA carriers
  • Determine how best to educate children and other family members of BRCA carriers
  • Create and improve personalized risk assessment and prevention options
  • Increase patient enrollment in clinical trials and research studies

Cancer Prevention

  • Launch medication prevention trials
  • Initiate preventative vaccine trials
  • Discover other molecular and genetic targets for cancer prevention
  • Understand the role of molecules that modify genes in the development of breast and ovarian cancer in BRCA carriers

Early Detection

  • Develop novel imaging techniques, including molecular imaging, to improve early detection
  • Discover novel cancer biomarkers
  • Develop miniaturized antibodies to improve imaging of early cancers


  • Launch and expand clinical trials
  • Determine effect of PARP inhibitors on improving standard of care
  • Develop treatment vaccines
  • Deepen understanding of treatment resistance patterns
  • Expand immunotherapy treatments