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Peripheral Arterial Disease (PAD)

Lee Kirsky, MD, talks about the latest advances in PAD and answers your questions. Listen Now >>

Approximately 8-12 million Americans are currently affected by a condition known as peripheral arterial disease (PAD). Though under-diagnosed, this condition is quite common, especially in older men aged 50 plus. According to the U.S. Department of Health and Human Services, peripheral arterial disease affects about 1 in 20 people over the age of 50, but only a quarter of those suffering from PAD are currently receiving treatment.

About the Disease
Peripheral arterial disease is a condition in which fatty plaque builds up in the (peripheral) arteries that supply blood to the extremities, including the legs and, in more rare cases, the arms. Over time, these buildups can potentially increase to the point where they completely block important blood vessels. Extreme cases involving the blockage of a vital artery can lead to the loss of a limb or even death.

People are at higher risk for PAD if they have:

  • personal or family history of heart disease or stroke
  • diabetes
  • smoking
  • hypertension
  • kidney disease involving hemodialysis

If you have poor circulation of the blood in your legs, you may have also reduced blood flow to your heart or brain, which can lead to heart attack or stroke. In fact, people with PAD are at a greatly increased risk of heart attack or stroke and death.

Symptoms can vary between patients but, with the help of a doctor, peripheral aterial disease can usually be controlled with treatment.

Diagnosis and Evaluation
The initial evaluation involves the non-invasive diagnosis of the level and extent of the disease. As common forms of rehabilitation, exercise and medical therapy may signifigantly improve pain-free walking distance.

Medical Therapy
If diagnosed with PVD, your first step is to talk with your physician about creating a treatment plan that is appropriate for you. Treatment of peripheral vascular disease generally focuses on the relief of symptoms and self-care to improve circulation. In some cases, medical therapy may be required to control the disorder, including pain relievers, blood thinners, and medications to enlarge or dilate the affected artery(ies).

Minimally Invasive and Surgical Treatment
Surgery is often performed in severe cases in which PAD affects the patient's ability to work or pursue essential activities. Surgery may consist of removing the lining of the artery, or repairing or replacing the vessel; most commonly, bypass surgery is performed, using a vein or synthetic graft. Alternatives to surgery may include minimally invasive procedures such as balloon angioplasty, sometimes followed by stent implantation, or other treatments.

Self-care
Self-care is an important component of treatment for persons with peripheral aterial disease. For patients experiencing the effects of PAD, exercise must be balanced with rest. Walking or other activities, performed to the point of pain and alternated with rest periods, is also often recommended. Over time, circulation improves because of the development of small, new blood vessels.

A healthy lifestyle and frequent check-ups are the best protection from peripheral aterial disease and its potentially devastating results. It is important for patients with PAD to avoid smoking, because it constricts arteries and decreases the blood's ability to carry oxygen, which in turn increases the risk of forming new clots. Finally, it is important to wear shoes that fit and pay attention to any cuts, scrapes or injury. If there is decreased circulation caused by PAD, the skin will take longer to heal.

If you are experiencing the above symptoms or feel that you might be at risk due to certain risk factors, see your doctor immediately. If left untreated, PAD can lead to gangrene, an infectious condition that may necessitate amputation. Patients with PAD also have a higher risk of death from a stroke or heart attack due to the clotting of blood vessels caused by the disease.

Research Studies
Researchers at the University of Pennsylvania Health System are investigating several therapies to improve lifestyle and longevity of patients with PAD. Speak to your doctor to learn more about research studies.

 


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