Research interests: Research in my laboratory is geared towards studying medically relevant aspects of digestive organ development.
Keywords: Zebrafish and mouse genetics, developmental biology, cancer, chemical genetics
Research details: Using the zebrafish system, we have applied genetics, gene targeting methodologies and pharmacological analyses to questions pertaining to growth, differentiation and survival of progenitor cells in the intestine, liver and pancreas. Through the positional cloning of zebrafish mutants our studies have led us in a number of directions.
Maintenance of Tissue Architecture