Pathology & Laboratory Medicine at HUP
Anatomic Pathology Division
Laboratory Medicine Division
University of Pennsylvania Pathology Laboratories
Neuropathology Division
Transfusion Medicine and Therapeutic Pathology Division

Anatomic Pathology Division

The Anatomic Pathology Division provides diagnosis of diseases and monitoring of therapy by examining tissues and cells, utilizing the latest techniques for the diagnosis of neoplastic, inflammatory and transplant-related diseases. The division is divided into three sections: cytopathology, medical pathology and surgical pathology.

Kumarasen Cooper, MBChB, DPhil


This section serves as a referral center for diagnosis based on examination of cellular material. Diseases of the thyroid, lung, gynecologic organs, kidney and lymph nodes are evaluated.

Cindy McGrath, MD

Cytogenetics Laboratory

This laboratory performs chromosome analysis in diagnosing and classifying leukemias and other hematologic disorders.

Medical Director
Adam Bagg, MD

Scientific Director
Jennifer Morrissette, PhD

Medical Pathology

This section diagnoses diseases at autopsy and utilizes various techniques including electron microscopy.

Leslie A. Litzky, MD

Electron Microscopy

This laboratory examines tissues at high magnification to detect changes in cell components in the diagnosis of lung, renal and cardiac diseases as well as cancers of various organs. Element analysis by X-ray diffraction of small tissue samples is performed in association with electron microscopy to aid in interpretation.

Surgical Pathology

This section is a referral center for diagnosis of malignant tumors of the breast, thyroid, uterus and ovaries, head and neck, lymphatic organs and lung. Diagnoses of neoplastic and non-neoplastic (inflammatory) diseases are also rendered.

Kathleen Montone, MD


The IHC lab is a comprehensive lab that employs state-of-the-art automation and technology to provide outstanding IHC staining for hundreds of targets in human tissue. The IHC lab also performs FISH assays for prognosis and diagnosis of solid tumors and assessment of breast cancer markers (both IHC and FISH) for patient care. Given the IHC labís technical and professional expertise, it is well equipped to develop and apply new tests for clinical trials. The lab offers frequent consultations with various technical and regulatory issues for outside laboratories and serve as a reference lab for various tests for the hospitals in the region.

Paul J. Zhang, MD


This laboratory evaluates diagnostic specimens using recent techniques to localize tumor antigens in melanomas, carcinomas and sarcomas, including intermediate filament protein and hormonal markers such as keratin, alpha-fetoprotein, human chorionic gonadotropin and calcitonin. Reagents are available for localization of various infectious agents.

Metabolic Bone Laboratory

Non-neoplastic bone lesions, osteoporosis, and nutritional bone disorders are evaluated qualitatively and quantitatively.

Molecular Diagnosis

Solid tumor evaluation of small round cell tumors and bone and soft tissue sarcomas is offered in order to subclassify these lesions at the genetic level.

Renal Pathology

Evaluation of kidney and urology diseases, transplant rejection phenomena, and other disorders by means of light microscopic immunofluorescence and electron microscopy.


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