Cerebrovascular research at Penn is focused on molecular mechanisms of brain injury and survival for the purpose of discovering new therapies for cerebral ischemia. The laboratory at Penn is equipped to produce both global and focal cerebral ischemia in rodent models. A variety of physiologic, pathologic, cellular and molecular biologic techniques are currently in use.
The research is carried out under the direction of Frank Welsh, PhD and Katalin Kariko, with the assistance of postdoctoral fellows and neuroscience graduate students. Neurosurgery residents have also contributed greatly to the productivity of the laboratory during their research training.
The labs are located in the heart of the medical school (Stemmler Hall), only minutes away from the neurosurgery clinical offices.