Penn Center for Cranial Base Surgery

Treatments for Skull Base Tumors

Penn neurosurgeons provide the best medical, surgical, and therapeutic approaches in the treatment of both benign and malignant tumors in the skull base, sinuses and brain.

The Penn Center for Cranial Base Surgery offers patient the latest therapies, including:

  • Restorative and reconstructive facial and skull base surgery
  • Minimally invasive endoscopic surgical techniques
  • Advanced microscopic, laser and ultrasonic techniques

Gamma Knife® Radiosurgery

Penn neurosurgeons are taking the treatment of skull base tumors to a new and greater level of efficacy with the use of Gamma Knife® radiosurgery. Penn Medicine is among the few centers in the country treating benign and malignant tumors of the anterior, middle and posterior cranial base with Gamma Knife radiosurgery, one of the most precise, powerful, and proven treatments for brain disorders.

The Gamma Knife is a highly advanced machine that delivers a powerful dose of radiation to a precise target in the brain. Patients experience little or no discomfort during the procedure. Patients usually go home the same day, and are generally able to resume normal activities almost immediately.

Proton Therapy

Penn's Roberts Proton Therapy Center is the largest and most comprehensive proton therapy center in the world. Penn Medicine's proton therapy program is unique in many regards, including the ability to perform conformal beam radiation treatments. Conformal radiation therapy shapes the treatment beam to the shape of the tumor. Using 3-D maps of the tumor location, the beam is delivered from several directions and shaped, or conformed, to match the shape of the cancer. Conformal radiation therapy limits radiation exposure to nearby healthy tissue

Paralleling the delivery principles of intensity-modulated radiation therapy (IMRT) and its ability to shape the radiation beam to avoid radiation exposure to critical structures in the head and neck, proton therapy significantly reduces the potential for serious side effects of radiation. In addition to its program of neurocritical care and multimodality monitoring, the Center provides fully equipped rehabilitation services and programs.

Gamma Knife and Leksell Gamma Knife are U.S. federally registered trademarks of Elekta Instrument S.A., Geneva, Switzerland.