Diagnosis and Evaluation
The Penn Brain Tumor Center is supported by the most advanced diagnostic tools available:
- Advanced MRI techniques including magnetic resonance spectroscopy (metabolic scanning), perfusion MRI to determine tumor blood volume and diffusion tractography to visualize specific white matter tracts.
- Neuromonitoring during surgery to identify and preserve cranial nerves (affecting vision, hearing, balance, facial expressions, speech and swallowing), motor mapping (preserving strength) and language mapping (preserving speech).
- Genetic testing for brain tumors.
- High-resolution intraoperative MRI (3T) neuronavigation for image-guided neurosurgery to identify the precise location of tumors in relation to surrounding brain fiber tracts. The surgeon develops a precise, personalized "road-map" of tumors in relation to key fiber tracts to achieve the goal of "maximal safe resection."
- Frameless MRI-based stereotactic biopsy.
- Positron emission tomography (PET) three-dimensional nuclear imaging.
Neuropsychology is an important component of the Penn Brain Tumor Center. Neuropsychologists work within the field of psychology and focus on brain-behavior relationships.
Pre- and post-surgical neuropsychological assessments provide information regarding the individual's cognitive strengths and weaknesses. This comprehensive process evaluates the patient's:
- Visual-spatial perception
- Executive functioning
Extensive language testing helps to guide awake brain mapping as an integral part of the pre-surgical process.
Neuropsychological evaluations also address patient and family education; and recommendations for rehabilitation, disability concerns, and work/school accommodations.