Penn Medicine Neuroscience Center: The Stroke Center

Penn Stroke Center

The Penn Stroke Center offers comprehensive, compassionate, state-of-the-art care for people who have had a stroke or other critical neurologic conditions. In addition, patients at risk for stroke are evaluated and preventative strategies and risk-factor modification instituted. Our center provides innovative and investigational treatments for stroke and critical neurologic conditions in an atmosphere of compassion and professionalism.

team and patient

Every effort is made to provide continuing information and support for you and your families. You'll benefit from the combined expertise of neurologists, neurointensivists, neurosurgeons, neuroradiologists and specially trained advanced practice neuroscience nurses. In addition, care is provided by dedicated physical therapists, occupational therapists, speech pathologists, neuropsycologists and rehabilitation medicine physicians.


Research is an important part of the stroke center. Clinicians in the stroke center are active in ongoing clinical research and collaborate with scientists from many and varied disciplines to determine why strokes occur, who is at risk for stroke, how best to diagnose and evaluate a stroke patient, what is the best management and how can recovery be stimulated.

team at work

Members of the stroke center also collaborate with Cardiologists, Interventional cardiologists and cardiac surgeons to ensure that all causes of stroke are addressed.

The Penn Stroke Center offers:

  • State-of-the-art diagnosis, treatment and prevention of stroke
  • Carotid ultrasonography
  • Transcranial Doppler studies
  • Noninvasive embolus detection
  • MRI, including diffusion and perfusion imaging
  • MR- angiography
  • CT, CT-Angiography
  • PET (positron emission tomography)
  • Diagnostic and interventional angiography

The Center offers both traditional and advanced treatment approaches, including:

  • Risk-factor modification
  • Medical prevention of stroke
  • Acute thrombolytic therapy
  • Clinical trials of new stroke therapies administered as soon as possible after a stroke
  • Clinical trials of new approaches to stroke prevention
  • Carotid endarterectomy
  • Interventional neuroradiologic techniques (including angioplasty, stent replacement and thrombolysis)
  • State-of-the-art neuro-intensive care unit and multimodality monitoring
  • Bypass and revascularization
  • Surgery for stroke


Comprehensive Stroke Center
Penn Medicine Neuroscience Center
Hospital of the University of Pennsylvania
3400 Spruce Street
2nd Floor, Ravdin Building
Philadelphia, PA 19104

Primary Stroke Centers
Penn Medicine Neuroscience Center
Pennsylvania Hospital
330 S. 9th Street
3rd Floor, Neurology
Philadelphia, PA 19107

Penn Medicine Neuroscience Center
Penn Presbyterian Medical Center
51 N. 39th Street
Philadelphia, PA 19104

Primary Stroke Center certification requirements include implementing evidence based protocols and collecting the Joint Commission core measure data to use in performance improvement activities. Comprehensive Stroke Center certification requirements include advanced imaging capabilities and 24/7 availability of specialized treatments. The mix of Primary Stroke Centers and HUP's Comprehensive Stroke Center allows Penn Medicine to address the needs of stroke patients throughout the Philadelphia region.


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Need an appointment? Request one online 24 hours/day, 7 days/week or call 800-789-PENN (7366) to speak to a referral counselor.

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