Interventional Radiology

Penn Interventional Radiology Research

One of the missions of Penn Interventional Radiology is to contribute to the science and art of interventional radiology through high quality research. To accomplish this goal, we actively conduct pre-clinical basic science, clinical research, and prospective trials.

The basic science arm of our research enterprise is the Penn Image-Guided Intervention (PIGI) Laboratory. PIGI Lab is dedicated to the translational investigation of a multitude of topics of interest to interventional radiology as well as the broader medical community. Current, active projects include the use of ultrasound for targeted tumor therapy, in vitro and in vivo investigation of the metabolic stress response of hepatocellular carcinoma, and novel methods of imaging of neo-intimal hyperplasia.

Penn Interventional Radiology has a rich tradition of clinical research with numerous enduring contributions to the practice of our specialty. The division contains internationally recognized experts in all major areas of practice. Particular areas of expertise and active clinical research include:

  • Interventional Oncology and minimally invasive cancer therapy
  • Hemodialysis access and intervention
  • Venothromboembolic disease and varicose vein treatments
  • Embolization of pulmonary arteriovenous malformations
  • Biliary Interventions
  • Transjugular intrahepatic portosystemic shunt (TIPS) creation and management
  • Peripheral arterial disease
  • Lymphatic malformation, thoracic duct leaks and embolization

Additionally, Penn Interventional Radiology advances patient care by conducting its own investigator lead prospective clinical trials as well as participating in several industry-sponsored trials. Examples of current trials include:

  • Multimodality therapy and novel therapies to treat liver cancer
  • Inferior vena cava filter placement
  • Management of malignant ascites
  • Treatment outcomes of symptomatic central vein stenosis