Infectious Disease Services at Penn Presbyterian
 
Infectious Disease Services at Penn Presbyterian
Services and Programs
Research and Clinical Trials
About Our Team
 

Research and Clinical Trials

Penn Community Practice at Penn Presbyterian Medical Center have conducted numerous research studies focused on the treatment and clinical outcomes of chronic viral hepatitis infection, especially in the HIV population. Recent studies have examined:

  • The incidence and risks factors for weight loss during dual HIV and hepatitis C virus therapy.
  • Measurement of adherence to pegylated interferon and ribavirin hepatitis C therapy.
  • The prevalence, risk factors, and clinical significance of occult hepatitis B virus infection in HIV-infected patients.

Active research is focused on elucidating additional risk factors for end-stage liver disease among HIV/hepatitis C-coinfected patients.

Clinical Trials
Penn Community Practices at Penn Presbyterian Medical Center participate are active in the following clinical trial:

Efficacy of Nitazoxanide Plus Peginterferon Alfa-2a and Ribavirin in Chronic Hepatitis C Treatment-Naïve Genotype 1 Subjects with HIV Coinfection (not yet available): This clinical trial will examine the addition of nitazoxanide to the current standard of care of 48 weeks of pegylated interferon and ribavirin among HIV and hepatitis C genotype 1-coinfected patients who have not received prior therapy for hepatitis C. Nitazoxanide is currently approved by the U.S. Food and Drug Administration (FDA) for the treatment of parasitic infections. The addition of this medication has been associated with improved hepatitis C treatment responses in clinical trials performed in hepatitis C-infected patients without HIV.

 


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Need an appointment? Request one online 24 hours/day, 7 days/week or call 800-789-PENN (7366) to speak to a referral counselor.

Related Links
Find an Infectious Disease Specialist at Penn Presbyterian
Request an Appointment Online or call
800-789-PENN (7366)
Penn Presbyterian Visitor Information
Encyclopedia Articles about Infectious Diseases

 

   
   

 

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