Penn Heart and Vascular

Innovations in Heart Failure at the Ventricular-Assist Device Program

Quality & Outcomes: Innovations in Heart Failure

Surgeons with the Penn Heart & Vascular Center are participating in the development of the following ventricular assist devices:

  • ADVANCE: Evaluation of the HeartWare® Left Ventricular Assist Device for the Treatment of Advanced Heart Failure
    This study will evaluate the safety and effectiveness of the HeartWare® LVAD System as a bridge-to-transplantation in patients listed for cardiac transplantation with refractory, advanced heart failure at risk of death.
  • ENDURANCE: Evaluation of the HeartWare® Ventricular Assist System
    This study will investigate the safety and effectiveness of the HeartWare Ventricular Assist System in patients with chronic Stage D/NYHA Class IIIB/IV left ventricular failure who have received and failed optimal medical therapy, and who are ineligible for cardiac transplantation.
  • REVIVE-IT: Randomized Evaluation of VAD InterVEntion before Inotropic Therapy
    This study will compare whether non-transplant eligible patients with heart failure less advanced than that of current LVAD recipients do better with implanted devices than with current medical therapy.

Penn Heart & Vascular Clinical Activity Reports

See Interactive Report or Download PDF Version

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