Penn Heart and Vascular

Innovations at the Heart Failure Program

Quality & Outcomes: Innovations in Heart Failure

Surgeons with the Penn Heart & Vascular Center are participating in the development of the following ventricular assist devices:

  • ADVANCE: Evaluation of the HeartWare® Left Ventricular Assist Device for the Treatment of Advanced Heart Failure
    This study will evaluate the safety and effectiveness of the HeartWare® LVAD System as a bridge-to-transplantation in patients listed for cardiac transplantation with refractory, advanced heart failure at risk of death.
  • ENDURANCE: Evaluation of the HeartWare® Ventricular Assist System
    This study will investigate the safety and effectiveness of the HeartWare Ventricular Assist System in patients with chronic Stage D/NYHA Class IIIB/IV left ventricular failure who have received and failed optimal medical therapy, and who are ineligible for cardiac transplantation.
  • REVIVE-IT: Randomized Evaluation of VAD InterVEntion before Inotropic Therapy
    This study will compare whether non-transplant eligible patients with heart failure less advanced than that of current LVAD recipients do better with implanted devices than with current medical therapy.

2012 Penn Heart Failure Clinical Activity Report

Download or view interactive report