Penn Heart and Vascular

Research and Clinical Advancements in the Adult Congenital Heart Disease Program

Quality & Outcomes: Research and Clinical Advances

Percutaneous Pulmonary Valve Replacement

Surgical repair of common cyanotic congenital heart defects in infancy often results in marked anatomic distortion of the pulmonary arteries and pulmonary valve insufficiency and may lead to right ventricular failure in adulthood. To address this, researchers at Penn Medicine’s Gorman Cardiovascular Research Group (GCRG) in collaboration with Matthew Gillespie, MD, an interventional cardiologist at CHOP, are working to develop novel approaches to minimally invasive pulmonary valve replacement. Currently, CHOP interventional cardiologists with the Philadelphia Adult Congenital Heart Center offer the Melody® transcatheter pulmonary valve replacements in select patients with congenital heart disease.

Advanced Cardiovascular Imaging Techniques and Intervention

Noninvasive magnetic resonance imaging (MRI) is used to delineate anatomy and physiology of congenital heart disease and is uniquely suited to guiding diagnostic and interventional cardiology procedures. X-ray magnetic resonance, also known as XMR, is a new technology in which soft tissue characterization and spatial localization afforded by MRI are used to improve catheter manipulation, decrease procedural time, and ultimately minimize radiation exposure in the catheterization suite. The Philadelphia Adult Congenital Heart Center is partnering with CHOP interventionalist Yoav Dori, MD, to develop standard protocols for XMR-guided cardiac catheterization in the adult congenital heart disease patient.

Penn Heart & Vascular Clinical Activity Reports

See Interactive Report or Download PDF Version

Upcoming Events