The test is usually done in the hospital. Before the test is done, you may be given a medicine to prevent pain or to calm you (sedative).
If the biopsy is done through the abdominal wall, you will be lying on your back with your right hand under your head. It is important to be as still as possible.
The health care provider will determine the correct spot for the biopsy needle to be inserted into the liver. The skin will be cleansed, and a small needle will be used to to inject medicine to numb the area. A small cut is made, and the biopsy needle is inserted. Ultrasound is usually used to guide the needle.You will be told to hold your breath while the biopsy is taken. This is to reduce the chance of puncturing the lung or tearing the liver.
The needle is removed quickly. Pressure will be applied to stop the bleeding. A bandage is placed over the insertion site.
The procedure can also be done by inserting a needle into the jugular vein. If the procedure is performed this way, you will lie on your back. X-rays will be used to guide the health care provider to the vein. A special needle and catheter (thin tube) is used to take the biopsy sample.
If you receive sedation for this test, you will need someone to drive you home.