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Alternative Names:
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ApoCII; Apoprotein CII; ApoC2
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How the test is performed:
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A blood sample is needed. For information on how this is done, see: Venipuncture
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How to prepare for the test:
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You may be told not to eat or drink anything for 4 - 6 hours before the test.
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Why the test is performed:
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ApoCII measurements can help to determine the specific type or cause of high blood lipids (hyperlipidemia).
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Normal Values:
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The normal range is 3 - 5 mg/dL. However, apo CII is usually reported as present or absent.
Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
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What abnormal results mean:
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High levels of apoCII may be due to:
Low apoCII levels are seen in persons with a rare condition called familial apoprotein CII deficiency. This causes chylomicronemia syndrome.
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What the risks are:
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Veins and arteries vary in size from one patient to another and from one side of the body to the other. Obtaining a blood sample from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight but may include:
- Excessive bleeding
- Fainting or feeling light-headed
- Hematoma (blood accumulating under the skin)
- Infection (a slight risk any time the skin is broken)
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Special considerations:
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Apolipoprotein measurements may provide more detail about your risk for heart disease, but the added value of this test beyond a lipid panel is unknown.
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References:
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Genest J, Libby P. Lipoprotein disorders and cardiovascular disease. In: Bonow RO, Mann DL, Zipes DP, Libby P, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 9th ed. Philadelphia, PA:Saunders Elsevier; 2011:chap 47.
Semenkovich, CF. Disorders of lipid metabolism. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 213.
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