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Chlamydia


Definition:

Chlamydia is an infection caused by the bacteria Chlamydia trachomatis. It is most commonly sexually transmitted.

Causes:

Chlamydia infection is the most common sexually transmitted infection in the United States. Sexually active individuals and individuals with multiple partners are at highest risk.

Symptoms:

As many as 25% of  men with chlamydia have no symptoms. In men, chlamydia may produce symptoms similar to gonorrhea. Symptoms may include:

  • Burning sensation during urination
  • Discharge from the penis or rectum
  • Testicular tenderness or pain
  • Rectal discharge or pain

About 70% of women with chlamydia have no symptoms. Symptoms that may occur in women include:

See also: Chlamydia in women

Exams and Tests:

The diagnosis of chlamydia infection involves sampling of the urethral discharge in males or cervical secretions in females. If an individual engages in anal sexual contact, samples from the rectum may also be needed. The sample is sent for a fluorescent or monoclonal antibody test, DNA probe test, or cell culture. Some of these tests may also be performed on urine samples.

Treatment:

The usual treatment for chlamydia is antibiotics, including tetracyclines, azithromycin, or erythromycin.

You can get chlamydia with gonorrhea or syphilis, so if you have one sexually transmitted infection you must be screened for other sexually transmitted infections as well. All sexual contacts should be screened for chlamydia.

Sexual partners must be treated to prevent passing the infection back and forth. There is no significant immunity following the infection and a person may become repeatedly infected.

A follow-up evaluation may be done in 4 weeks to determine if the infection has been cured.

Outlook (Prognosis):

Early antibiotic treatment is extremely successful and may prevent the development of long-term complications. Untreated infection, however, may lead to complications.

Possible Complications:

Chlamydia infections in women may lead to inflammation of the cervix. In men, chlamydia infection can lead to inflammation of the urethra called urethritis.

An untreated chlamydia infection may spread to the uterus or the fallopian tubes, causing salpingitis or pelvic inflammatory disease. These conditions can lead to infertility and increase the risk of ectopic pregnancy.

If a women is infected with chlamydia while pregnant, the infection may cause infection in the uterus after delivery (late postpartum endometritis). In addition, the infant may develop chlamydia-related conjunctivitis (eye infection) and pneumonia. See: chlamydial pneumonia

When to Contact a Medical Professional:

Call your health care provider if you have symptoms of chlamydia.

Because many people with chlamydia may not have symptoms, sexually active adults should be screened periodically for the infection.

Prevention:

All sexually active women up through age 25 should be screened yearly for chlamydia. All women with new sexual partners or multiple partners should also be screened.

A mutually monogamous sexual relationship with an uninfected partner is one way to avoid this infection. The proper use of condoms during intercourse usually prevents infection.

References:

U.S. Preventive Services Task Force. Screening for chlamydial infection: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2007;147:128-134.

Geisler WM. Diseases caused by chlamydiae. In: Goldman L, Shafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier; 2011:chap 326.

Centers for Disease Control and Prevention. Sexually Transmitted Diseases Treatment Guidelines. 2010 MMWR. 2010;59(RR-12):1-110.


Review Date: 5/31/2012
Reviewed By: Susan Storck, MD, FACOG, Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Bellevue, Washington; Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc.

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