Search Encyclopedia:    
List of Topics Print This Page
 

Scleroma


Definition:

A scleroma is a hardened patch of tissue in the skin or mucous membranes. It usually forms in the head and neck. The nose is the most common location for scleromas, but they can also form in the throat and upper lungs.

A scleroma can form when a chronic bacterial infection causes inflammation, swelling, and scarring in the tissues. They are most common in Central and South America, Africa, the Middle East, Asia, India and Indonesia. Scleromas are rare in the United States and Western Europe. Treatment may require surgery and a long course of antibiotics.

Alternative Names:

Induration; Rhinoscleroma

References:

Donnenberg MS. Enterobacteriaceae. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 8th ed. Philadelphia, PA: Elsevier Churchill Livingstone; 2014:chap 220.

Fawaz S, Tiba M, Salman M, Othman H. Clinical, radiological and pathological study of 88 cases of typical and complicated scleroma. Clin Respir J. 2011;5(2):112-21.


Review Date: 4/28/2015
Reviewed By: Gordon A. Starkebaum, MD, professor of Medicine, Division of Rheumatology, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2002 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

   View History
  Scleroma

Related Links
Request an Appointment Online or call
1-800-789-PENN (7366)
   
   

 

About UPHS   Contact Us   Site Map   Privacy Statement   Legal Disclaimer   Terms of Use

The University of Pennsylvania Health System, Philadelphia, PA 1-800-789-PENN © 2016, The Trustees of the University of Pennsylvania