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Renal vein thrombosis


Definition:

Renal vein thrombosis is a blood clot that develops in the vein that drains blood from the kidney.

Alternative Names:

Blood clot in the renal vein; Occlusion - renal vein

Causes:

Renal vein thrombosis is an uncommon disorder. It may be caused by:

In adults, the most common cause is nephrotic syndrome. In infants, the most common cause is dehydration.

Symptoms:
Exams and Tests:

An exam may not reveal the specific problem. However, it may indicate nephrotic syndrome or other causes of renal vein thrombosis.

Tests include:

Treatment:

The treatment is focused on preventing new clot formations and reducing the risk of the clot traveling to other locations in the body (embolization).

You may get medicines that prevent blood clotting (anticoagulants). Your doctor may have rest in bed or cut down on activity for a short time.

If sudden kidney failure develops you may need dialysis for a short period.

Outlook (Prognosis):

Renal vein thrombosis usually gets better over time without lasting damage to the kidneys.

Possible Complications:
  • Acute renal failure (especially if thrombosis occurs in a dehydrated child)
  • End stage renal disease
  • Blood clot moves to the lungs (pulmonary embolism)
  • Formation of new blood clots
When to Contact a Medical Professional:

Call your health care provider if you have symptoms of renal vein thrombosis.

If you have experienced renal vein thrombosis, call your health care provider if you have:

Prevention:

In most cases, there is no specific way to prevent renal vein thrombosis. Keeping enough fluids in the body may help reduce risk.

Aspirin is sometimes used to prevent renal vein thrombosis in people who have had a kidney transplant. Blood thinners such as warfarin may be recommended in some people with chronic kidney disease.

References:

DuBose TD Jr, Santos RM. Vascular disorders of the kidney. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 127.

Ruggenenti P, Cravede P, Remuzzi G. Microvascular and macrovascular diseases of the kidney. In: Taal MW, Chertow GM, Marsden PA, et al, eds. Brenner and Rector's The Kidney. 9th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 34.


Review Date: 7/2/2013
Reviewed By: Melissa B Bleicher, MD, Division of Renal, Electrolyte, and Hypertension, Hospital of the University of Pennsylvania, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Bethanne Black, and the A.D.A.M. Editorial team.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2002 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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